Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lewis F. Neville"'
Publikováno v:
Journal of Antimicrobial Chemotherapy. 77:1706-1709
Objectives STM-001, a retargeted glycopeptide, is active against MDR E. coli expressing ESBLs including carbapenemases. Herein, we assessed its capability to combat E. coli complicated urinary tract infections (cUTI) in mice driven by clinically impo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fec636213def06b334513bbb40971fb
https://doi.org/10.1093/jac/dkac063
https://doi.org/10.1093/jac/dkac063
Autor:
Sabrina H. Werby, Jasna Brcic, Madeline B. Chosy, Jiuzhi Sun, Jacob T. Rendell, Lewis F. Neville, Paul A. Wender, Lynette Cegelski
Publikováno v:
RSC Medicinal Chemistry.
The introduction of new and improved antibacterial agents based on facile synthetic modifications of existing antibiotics represents a promising strategy to deliver urgently needed antibacterial candidates to treat multi-drug resistant...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::91daa7fbbd1aea6f29a5909b73be9c70
https://doi.org/10.1039/d3md00173c
https://doi.org/10.1039/d3md00173c
Autor:
Jacob T. Rendell, Marc H. Scheetz, Lynette Cegelski, Itamar Shalit, Jiuzhi Sun, Madeline B. Chosy, Peter Warn, Paul A. Wender, Lewis F. Neville
Publikováno v:
Antimicrobial Agents and Chemotherapy
The ability of vancomycin-arginine (V-r) to extend the spectrum of activity of glycopeptides to Gram-negative bacteria was investigated. Its MIC toward Escherichia coli, including β-lactamase expressing Ambler classes A, B, and D, was 8 to 16 μg/ml
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d983a1bfda900947f26a6e878c26937e
https://doi.org/10.1128/aac.02416-20
https://doi.org/10.1128/aac.02416-20
Autor:
Heribert Bohlen, S. A. Boehm, Cecilia Cu Zetina, G. Mathiak, Thomas Herzmann, Arnulf H. Hoelscher, Lewis F. Neville, Thomas Luebke, Guido Grass
Publikováno v:
British Journal of Pharmacology. 131:383-386
The effect of acetyl - tyrosyl-valyl-alanyl-aspartyl - chloromethylketone (ac-YVAD-cmk), an irreversible caspase-1 (IL-1beta converting enzyme, ICE) inhibitor on mortality, leukocyte and platelet counts and cytokine levels was investigated in a doubl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbb1f1bc3b41f45af5d371c0ecc776a2
https://doi.org/10.1038/sj.bjp.0703629
https://doi.org/10.1038/sj.bjp.0703629
Publikováno v:
Journal of Molecular Biology. 234:289-296
Acetyl- and butyrylcholinesterases (ACHE, BuChE) from various species differ in their substrate specificities and sensitivities to a wide range of inhibitors, yet display conserved sequence, structure and catalytic properties. To determine features t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::696d1e13652e761bb0c09a420d2e4c20
https://doi.org/10.1006/jmbi.1993.1584
https://doi.org/10.1006/jmbi.1993.1584
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 17:905-926
Yael Loewenstein, Averell Gnatt, Lewis F. Neville, Haim Zakut and Hermona Soreq: Structure-function relationship studies in human cholinesterases reveal genomic origins for individual variations in cholinergic drug responses. Prog. Neuro-Psychopharma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c70e2a903fb189babe978c186a2607ad
https://doi.org/10.1016/0278-5846(93)90019-o
https://doi.org/10.1016/0278-5846(93)90019-o
Autor:
Hermona Soreq, Gal Ehrlich, Lewis F. Neville, Yael Loewenstein, Shlomo Seidman, Averell Gnatt
Publikováno v:
The EMBO Journal. 11:1641-1649
Structure-function relationships of cholinesterases (CHEs) were studied by expressing site-directed and naturally occurring mutants of human butyrylcholinesterase (BCHE) in microinjected Xenopus oocytes. Site-directed mutagenesis of the conserved ele
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8a60cd20a22513960f8c000670a3098
https://doi.org/10.1002/j.1460-2075.1992.tb05210.x
https://doi.org/10.1002/j.1460-2075.1992.tb05210.x
Publikováno v:
Journal of Neuroscience Research. 27:452-460
The "atypical" allelic variant of human butyrylcholinesterase (BuChE) can be characterized by its failure to bind the local anesthetic dibucaine, the muscle relaxant succinylcholine, and the naturally occurring steroidal alkaloid solanidine, all assu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::523285c6515cf8ab46ba84648d2c7a65
https://doi.org/10.1002/jnr.490270404
https://doi.org/10.1002/jnr.490270404
Autor:
Y Lipidot-Lifson, Shlomo Seidman, Judy Lieman-Hurwitz, Dalia Ginzberg, Catherine A. Prody, Hermona Soreq, Efrat Lev-Lehman, Lewis F. Neville, Averell Gnatt, Revital Ben-Aziz
Publikováno v:
Proceedings of the National Academy of Sciences. 87:9688-9692
To study the primary structure of human acetylcholinesterase (AcChoEase; EC 3.1.1.7) and its gene expression and amplification, cDNA libraries from human tissues expressing oocyte-translatable AcChoEase mRNA were constructed and screened with labeled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff33f29a05a752a1a9838f608e380ed5
https://doi.org/10.1073/pnas.87.24.9688
https://doi.org/10.1073/pnas.87.24.9688
Autor:
Thomas Minor, Christoph Burger, Hendrik Keller, Koroush Kabir, Frank Stueber, Lewis F. Neville, G. Mathiak, C. Rangger, Stefan Schroeder, Christian Putensen, Christian Paul, Guido Grass
Publikováno v:
Scopus-Elsevier
The aim of this prospective cohort study was to address the feasibility of measuring cytokines in serum and urine as early predictor tests for the identification of septic Intensive Care Unit (ICU) patients. The study group consisted of 10 septic and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90ed953ea57bbff44d9760be00ef2b0d
https://pubmed.ncbi.nlm.nih.gov/12964035
https://pubmed.ncbi.nlm.nih.gov/12964035