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Antibody-antigen binding affinity lies at the heart of therapeutic antibody development: efficacy is guided by specific binding and control of affinity. Here we present Graphinity, an equivariant graph neural network architecture built directly from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a043171ece27c11118ff943fdd61051f
https://doi.org/10.1101/2023.05.17.541222
https://doi.org/10.1101/2023.05.17.541222
Publikováno v:
Bioinformatics (Oxford, England).
1AbstractSummaryThe development of new vaccines and antibody therapeutics typically takes several years and requires over $1bn in investment. Accurate knowledge of the paratope (antibody binding site) can speed up and reduce the cost of this process