Evaluating the sensitivity of newborn rats and newborn hamsters to oncogenic DNA.

Autor: Sheng-Fowler L; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Tu W; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Phy K; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Macauley J; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Lanning L; National Institute of Allergy and Infectious Diseases, National Institutes of Health, Rockville, MD, 20888, USA., Lewis AM Jr; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Peden K; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA. Electronic address: keith.peden@fda.hhs.gov.

Publikováno v: Biologicals : journal of the International Association of Biological Standardization [Biologicals] 2023 Nov; Vol. 84, pp. 101724. Date of Electronic Publication: 2023 Nov 16.

Responsiveness to basement membrane extract as a possible trait for tumorigenicity characterization.

Autor: Murata H; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Omeir R; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Tu W; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Lanning L; National Institute of Allergy and Infectious Diseases, Rockville, MD, USA., Phy K; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Foseh G; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Lewis AM Jr; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA., Peden K; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Silver Spring, MD, USA.

Publikováno v: Vaccine: X [Vaccine X] 2019 Jan 03; Vol. 1, pp. 100004. Date of Electronic Publication: 2019 Jan 03 (Print Publication: 2019).

A novel canine kidney cell line model for the evaluation of neoplastic development: karyotype evolution associated with spontaneous immortalization and tumorigenicity.

Autor: Omeir R; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Thomas R; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA.; Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, NC, 27607, USA., Teferedegne B; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Williams C; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA., Foseh G; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Macauley J; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Brinster L; Division of Veterinary Resources, National Institutes of Health, Bethesda, MD, 20892, USA., Beren J; Office of Counter-Terrorism and Emergency Coordination, Center for Drug Evaluation and Research, Food and Drug Administration, Silver Spring, MD, 20993, USA., Peden K; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA., Breen M; Department of Molecular Biomedical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Drive, Raleigh, NC, 27607, USA. matthew_breen@ncsu.edu.; Center for Comparative Medicine and Translational Research, North Carolina State University, Raleigh, NC, 27607, USA. matthew_breen@ncsu.edu.; Cancer Genetics Program, University of North Carolina Lineberger Comprehensive Cancer Center, Chapel Hill, NC, 27599, USA. matthew_breen@ncsu.edu.; Center for Human Health and the Environment, North Carolina State University, Raleigh, NC, 27607, USA. matthew_breen@ncsu.edu., Lewis AM Jr; Laboratory of DNA Viruses, Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, 10903 New Hampshire Ave, Silver Spring, MD, 20993, USA. andrew.lewis@fda.hhs.gov.

Publikováno v: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology [Chromosome Res] 2015 Dec; Vol. 23 (4), pp. 663-80. Date of Electronic Publication: 2015 May 10.

A mouse strain defective in both T cells and NK cells has enhanced sensitivity to tumor induction by plasmid DNA expressing both activated H-Ras and c-Myc.

Autor: Sheng-Fowler L; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Tu W; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Fu H; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Murata H; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Lanning L; National Institute of Allergy and Infectious Diseases, Rockville, Maryland, United States of America., Foseh G; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Macauley J; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Blair D; National Cancer Institute, Rockville, Maryland, United States of America., Hughes SH; Frederick Cancer Research Facility, National Cancer Institute, Frederick, Maryland, United States of America., Coffin JM; Frederick Cancer Research Facility, National Cancer Institute, Frederick, Maryland, United States of America; Tufts University, Boston, Massachusetts, United States of America., Lewis AM Jr; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America., Peden K; Division of Viral Products, Office of Vaccines Research and Review, Center for Biologics Evaluation and Research, Food and Drug Administration, Bethesda, Maryland, United States of America.

Publikováno v: PloS one [PLoS One] 2014 Oct 10; Vol. 9 (10), pp. e108926. Date of Electronic Publication: 2014 Oct 10 (Print Publication: 2014).

Development of Assays of Defined Sensitivity for the Regulatory Management of Novel Cell Substrates.

Publikováno v: Respiratory Therapeutics Week; 3/18/2024, p916-916, 1p