Zobrazeno 1 - 10
of 710
pro vyhledávání: '"Levodopa therapy"'
Autor:
Chenqing Wu, Haoting Wu, Cheng Zhou, Xiaojun Guan, Tao Guo, Jingjing Wu, Jingwen Chen, Jiaqi Wen, Jianmei Qin, Sijia Tan, Xiaojie Duanmu, Weijin Yuan, Qianshi Zheng, Baorong Zhang, Xiaojun Xu, Minming Zhang
Publikováno v:
Neurobiology of Disease, Vol 191, Iss , Pp 106406- (2024)
Background: Parkinson's disease (PD) patients exhibit an imbalance between neuronal activity and perfusion, referred to as abnormal neurovascular coupling (NVC). Nevertheless, the underlying molecular mechanism and how levodopa, the standard treatmen
Externí odkaz:
https://doaj.org/article/a3ab21a4346f48989db51ce6b16d9470
Less Pulsatile Levodopa Therapy (6 Doses Daily) Is Associated with a Reduced Incidence of Dyskinesia
Autor:
Mark M. Lin, Robert Laureno
Publikováno v:
Journal of Movement Disorders, Vol 12, Iss 1, Pp 37-42 (2019)
Objective To evaluate whether less pulsatile levodopa therapy (LPT) can reduce the development of levodopa-induced dyskinesia (LID). Methods This is a retrospective cohort study of patients with Parkinson’s disease at the movement disorders clinic
Externí odkaz:
https://doaj.org/article/4479c5f46af544fabca61e0e88a7e389
Autor:
Kyoko Hoshino, Masaharu Hayashi, Asayo Ishizaki, Kazue Kimura, Masaya Kubota, Atsuo Nezu, Akihiro Yasuhara
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Introduction: Post-synaptic dopamine receptor supersensitivity (DARSS) has been extensively researched by Dr. Masaya Segawa, who has investigated the efficacy of very-low-dose levodopa therapy (VLDT; 0.5–1 mg/kg/day). Considerable Japanese research
Externí odkaz:
https://doaj.org/article/baecdb05cef9458c98334008ea916bfc
Akademický článek
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Autor:
V.I. Tsymbaliuk, A.O. Popov
Publikováno v:
Ендоваскулярна нейрорентгенохірургія, Vol 24, Iss 2, Pp 30-36 (2018)
Objective — to investigate the dynamics of levodopa-therapy in patients with Parkinson's disease (PD) after unilateral stereotactic radiofrequency pallidotomy (USRP). Materials and methods. From 2008 to 2016 USRP was performed in 16 patients (7
Externí odkaz:
https://doaj.org/article/d08c1bbbfd9d4ceaaeb1421790499ec5
Autor:
Jarosław Sławek, Karol Grabowski, Piotr Wąż, Emilia J. Sitek, Agnieszka Konkel, Jarosław Dulski, Michał Schinwelski, Witold Libionka
Publikováno v:
Neuromodulation: Technology at the Neural Interface. 25:904-910
Introduction The study aimed at evaluating the effect of subthalamic deep brain stimulation (DBS-STN) on restless legs syndrome (RLS) in Parkinson's disease (PD) patients. Materials and methods We assessed the presence of RLS before, 6 and 12 months
Akademický článek
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K zobrazení výsledku je třeba se přihlásit.
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Autor:
Ruxandra Julia Vorovenci, Mihaela Simu, Cristina Bejinar, Inge Krabbendam, Amalia M. Dolga, Ioan Ovidiu Sirbu, Cristina Dijmarescu, Cecilia Rosca, Aimee Rodica Chis, Catalin Marian, Alexandra Ioana Moatar
Publikováno v:
Journal of Cellular and Molecular Medicine
Journal of cellular and molecular medicine, 25(18), 8715-8724. Wiley
Journal of cellular and molecular medicine, 25(18), 8715-8724. Wiley
Parkinson's disease (PD) is the second most common neurodegenerative disorder among the elderly, the diagnostic and prognostic of which is based mostly on clinical signs. LevoDopa replacement is the gold standard therapy for PD, as it ameliorates the
Publikováno v:
Biomolecules, Vol 9, Iss 4, p 142 (2019)
Levodopa (LD) is the most effective drug in the treatment of Parkinson’s disease (PD). However, although it represents the “gold standard„ of PD therapy, LD can cause side effects, including gastrointestinal and cardiovascular symptoms as well
Externí odkaz:
https://doaj.org/article/1aef129c6753401580ae085ea7ad91e2
Publikováno v:
Clinics in Geriatric Medicine. 36:43-52
Advanced Parkinson disease (PD) is characterized by the presence of motor fluctuations becoming the focus of treatment, prominent postural instability, significant disability despite levodopa therapy, and the presence of symptoms refractory to levodo