Výsledky vyhledávání - "Levodopa/administration & dosage/adverse effects"

Levodopa in the treatment of Parkinson's disease: an old drug still going strong

Autor: Pierre R. Burkhard, Jan Cm Zijlmans, François Vingerhoets, Werner Poewe, Angelo Antonini

Publikováno v: Clinical Interventions in Aging
Clinical Interventions in Aging, Vol. 5 (2010) pp. 229-38

After more than 40 years of clinical use, levodopa (LD) remains the gold standard of symptomatic efficacy in the drug treatment of Parkinson's disease (PD). Compared with other available dopaminergic therapies, dopamine replacement with LD is associa

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de29a5bf30d7a429458377d4b5eba73
https://pubmed.ncbi.nlm.nih.gov/20852670

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L-dopa-induced dyskinesia improvement after STN-DBS depends upon medication reduction

Autor: Jean-Guy Villemure, P Combrement, H. Russmann, François Vingerhoets, J. Ghika, Pierre Burkhard, Julien Bogousslavsky

Publikováno v: Neurology, Vol. 63, No 1 (2004) pp. 153-5

The authors studied the long-term evolution of levodopa-induced dyskinesia (LID) after levodopa challenge in two groups of six STN-deep brain stimulation-treated Parkinson disease (PD) patients, one requiring medication after surgery and the other no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3cbfa5574ccdab2d3e28d98c76904539
https://archive-ouverte.unige.ch/unige:45356

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Continuous transdermal dopaminergic stimulation in advanced Parkinson's disease

Autor: Spiridon Konitsiotis, William Bara-Jimenez, Thomas N. Chase, Holly Shill, Marge Gillespie, Leo Verhagen Metman, Francesco Bibbiani, Carrie M. Farmer, M. Maral Mouradian, M. J. Morris

The objective of the study was to determine the safety and efficacy of increasing doses of Rotigotine CDS in patients with advanced Parkinson's disease. The development of motor complications in Parkinson's disease has been linked to intermittent sti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af66509f005bf089ad036320f61d4a41
http://olympias.lib.uoi.gr/jspui/handle/123456789/22813

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Inhibition of levodopa effects by internal pallidal stimulation

Autor: Patricia Limousin, Pierre Pollak, Abdelhamid Benazzouz, Alim-Louis Benabid, Paul Krack, Dominique Hoffmann

Publikováno v: Movement Disorders, Vol. 13, No 4 (1998) pp. 648-52

We report three patients with bilateral GPi stimulation for stage 4 Parkinson's disease (PD) with severe levodopa-induced dyskinesias (LID). In all three it was possible to completely inhibit LID using high-stimulation parameters. Parallel to complet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a45b9da1d3eb5932cd691735259704
https://archive-ouverte.unige.ch/unige:94636

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Amantadine reduces levodopa-induced dyskinesias in parkinsonian monkeys

Autor: P J Blanchet, Thomas N. Chase, Spyridon Konitsiotis

The antidyskinetic potential of the glutamate NMDA receptor channel blocker amantadine was evaluated in four levodopa-primed parkinsonian monkeys using two different regimens (1.25 or 2.5 mg/kg administered subcutaneously twice daily for 3-6 days). W

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76b7a1d54e8c58c00b88df6f3b2e1f0d
http://olympias.lib.uoi.gr/jspui/handle/123456789/23946

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