Zobrazeno 1 - 10
of 1 676
pro vyhledávání: '"Levitz, P."'
Autor:
Alexa Strauss, Alberto J. Gonzalez-Hernandez, Joon Lee, Nohely Abreu, Purushotham Selvakumar, Leslie Salas-Estrada, Melanie Kristt, Anisul Arefin, Kevin Huynh, Dagan C. Marx, Kristen Gilliland, Bruce J. Melancon, Marta Filizola, Joel Meyerson, Joshua Levitz
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The metabotropic glutamate receptors (mGluRs) are neuromodulatory family C G protein coupled receptors which assemble as dimers and allosterically couple extracellular ligand binding domains (LBDs) to transmembrane domains (TMDs) to drive in
Externí odkaz:
https://doaj.org/article/6e48d6960b5240c69e16e202a52f5256
Autor:
Nevin John, Steve Vucic, Riadh Gouider, Tomas Kalincik, Guillermo Izquierdo, Alexandre Prat, Marc Girard, Pierre Duquette, Pierre Grammond, Serkan Ozakbas, Jeannette Lechner-Scott, Cavit Boz, Julie Prevost, Recai Turkoglu, Vincent Van Pesch, Cristina Ramo-Tello, Mark Slee, Raed Alroughani, Vahid Shaygannejad, Daniele Spitaleri, José Luis Sánchez-Menoyo, Suzanne Hodgkinson, Rana Karabudak, Tim Spelman, Helmut Butzkueven, Noriko Isobe, Paul G Sanfilippo, Michael Barnett, Orla Gray, Maria José Sá, Allan Kermode, Guy Laureys, Richard Macdonell, Anneke Van Der Walt, Ayse Altintas, Mario Habek, Pamela McCombe, Seyed Mohammad Baghbanian, Yi Chao Foong, Riki Matsumoto, Abdullah Al-Asmi, Bruce Taylor, Samia J Khoury, Todd Hardy, Katherine Buzzard, Marzena Fabis-Pedrini, Louise Rath, Olga Skibina, Jiwon Oh, William M Carroll, Katrin Gross-Paju, Jan Schepel, Sara Eichau, Elisabetta Cartechini, Aysun Soysal, Davide Maimone, Anoushka Lal, Masoud Etemadifar, Oliver Gerlach, Saloua Mrabet, Emanuele D'Amico, Yolanda Blanco, Matteo Foschi, Melissa Cambron, Andrea Surcinelli, David Levitz, Liesbeth Van Hijfte, Mehmet Fatih Yetkin, Simón Cárdenas-Robledo, Emmanuelle Lapointe, Abdorreza Naser Moghadasi, Gregor Brecl Jakob, Talal Al-Harbi
Publikováno v:
BMJ Neurology Open, Vol 6, Iss Suppl 1 (2024)
Externí odkaz:
https://doaj.org/article/fc8e0655ceeb42e4b6966e9c79930d0b
Autor:
Charles A. Specht, Ruiying Wang, Lorena V. N. Oliveira, Maureen M. Hester, Christina Gomez, Zhongming Mou, Diana Carlson, Chrono K. Lee, Camaron R. Hole, Woei C. Lam, Rajendra Upadhya, Jennifer K. Lodge, Stuart M. Levitz
Publikováno v:
mBio, Vol 15, Iss 8 (2024)
ABSTRACT The global burden of infections due to the pathogenic fungus Cryptococcus is substantial in persons with low CD4+ T-cell counts. Previously, we deleted three chitin deacetylase genes from Cryptococcus neoformans to create a chitosan-deficien
Externí odkaz:
https://doaj.org/article/06a1bf7a6e2243f584d221896bb3e019
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Chronic obstructive pulmonary disease (COPD) is a highly prevalent yet under-recognized and sub-optimally managed disease that is associated with substantial morbidity and mortality. Primary care providers (PCPs) are at the frontlines of COPD managem
Externí odkaz:
https://doaj.org/article/c24b7069704940fc86301e7156c20e08
Autor:
Ruiying Wang, Lorena V N Oliveira, Maureen M Hester, Diana Carlson, Dennis Christensen, Charles A Specht, Stuart M Levitz
Publikováno v:
PLoS Pathogens, Vol 20, Iss 7, p e1012220 (2024)
The fungal infection, cryptococcosis, is responsible for >100,000 deaths annually. No licensed vaccines are available. We explored the efficacy and immune responses of subunit cryptococcal vaccines adjuvanted with Cationic Adjuvant Formulation 01 (CA
Externí odkaz:
https://doaj.org/article/f95efdf0739045df975e52daceeaec34
Autor:
Christolyn Raj, Lewis Levitz
Publikováno v:
Case Reports in Ophthalmology, Vol 15, Iss 1, Pp 15-22 (2024)
Introduction: Two cases of late presentation (>5 years) of bilateral pseudophakic macula edema related to oral tyrosine kinase inhibitors are described. These cases are the first of their type in the published literature. A review of ocular inflammat
Externí odkaz:
https://doaj.org/article/8e1477b99d954a0b8e5969b9ac97985c
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Cryptococcus neoformans and C. gattii, the etiologic agents of cryptococcosis, cause over 100,000 deaths worldwide every year, yet no cryptococcal vaccine has progressed to clinical trials. In preclinical studies, mice vaccinated with an attenuated s
Externí odkaz:
https://doaj.org/article/cd822e4aaf3044ae875264ba6359ba7b
Autor:
Troy Anderson, Julia Mo, Ernesto Gagarin, Desmarie Sherwood, Maria Blumenkrantz, Eric Mao, Gianna Leon, Hailey Levitz, Hung-Jhen Chen, Kuo-Chang Tseng, Peter Fabian, J. Gage Crump, Joanna Smeeton
Publikováno v:
npj Regenerative Medicine, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract After traumatic injury, healing of mammalian ligaments is typically associated with fibrotic scarring as opposed to scar-free regeneration. In contrast, here we show that the ligament supporting the jaw joint of adult zebrafish is capable of
Externí odkaz:
https://doaj.org/article/980b8a7918d740818d172734a1009a9f
Publikováno v:
Case Reports in Ophthalmology, Vol 14, Iss 1, Pp 376-381 (2023)
Infective endophthalmitis is an uncommon complication following intraocular surgery. Chronic endophthalmitis may present some time after intraocular surgery, making the diagnosis challenging. Cutibacterium acnes is a well-recognised causative agent o
Externí odkaz:
https://doaj.org/article/38d900b0fa2a49c6a18d5c3d4cad31f2
Autor:
Minfei Su, Jinan Wang, Guoqing Xiang, Hung Nguyen Do, Joshua Levitz, Yinglong Miao, Xin-Yun Huang
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract α1-adrenergic receptors (α1-ARs) play critical roles in the cardiovascular and nervous systems where they regulate blood pressure, cognition, and metabolism. However, the lack of specific agonists for all α1 subtypes has limited our under
Externí odkaz:
https://doaj.org/article/63dfe8288c9a4a048a21d6655a5086b0