Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Levi B. Good"'
Autor:
Muhammed Shariff, Aksharkumar Dobariya, Obada Albaghdadi, Jacob Awkal, Hadi Moussa, Gabriel Reyes, Mansur Syed, Robert Hart, Cameron Longfellow, Debra Douglass, Tarek Y. El Ahmadieh, Levi B. Good, Vikram Jakkamsetti, Gauri Kathote, Gus Angulo, Qian Ma, Ronnie Brown, Misha Dunbar, John M. Shelton, Bret M. Evers, Sourav Patnaik, Ulrike Hoffmann, Amy E. Hackmann, Bruce Mickey, Matthias Peltz, Michael E. Jessen, Juan M. Pascual
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Selective vascular access to the brain is desirable in metabolic tracer, pharmacological and other studies aimed to characterize neural properties in isolation from somatic influences from chest, abdomen or limbs. However, current methods fo
Externí odkaz:
https://doaj.org/article/f27c134eed2846f4b5ca3dffb16c1331
Autor:
Aksharkumar Dobariya, Tarek Y. El Ahmadieh, Levi B. Good, Ana G. Hernandez-Reynoso, Vikram Jakkamsetti, Ronnie Brown, Misha Dunbar, Kan Ding, Jesus Luna, Raja Reddy Kallem, William C. Putnam, John M. Shelton, Bret M. Evers, Amirhossein Azami, Negar Geramifard, Stuart F. Cogan, Bruce Mickey, Juan M. Pascual
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/7f766811417c476fada6cdeaa60234a6
Autor:
Elysandra M. Solis, Levi B. Good, Rafael Granja Vázquez, Sourav Patnaik, Ana G. Hernandez-Reynoso, Qian Ma, Gustavo Angulo, Aksharkumar Dobariya, Stuart F. Cogan, Joseph J. Pancrazio, Juan M. Pascual, Vikram Jakkamsetti
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
Glucose represents the principal brain energy source. Thus, not unexpectedly, genetic glucose transporter 1 (Glut1) deficiency (G1D) manifests with encephalopathy. G1D seizures, which constitute a prominent disease manifestation, often prove refracto
Externí odkaz:
https://doaj.org/article/86266aa5aa284d798db3c4b1c8e80b58
Autor:
Aksharkumar Dobariya, Tarek Y. El Ahmadieh, Levi B. Good, Ana G. Hernandez-Reynoso, Vikram Jakkamsetti, Ronnie Brown, Misha Dunbar, Kan Ding, Jesus Luna, Raja Reddy Kallem, William C. Putnam, John M. Shelton, Bret M. Evers, Amirhossein Azami, Negar Geramifard, Stuart F. Cogan, Bruce Mickey, Juan M. Pascual
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Gyriform mammals display neurophysiological and neural network activity that other species exhibit only in rudimentary or dissimilar form. However, neural recordings from large mammals such as the pig can be anatomically hindered and pharmac
Externí odkaz:
https://doaj.org/article/34c32409f3464360b8cb3413a0b7d4dc
Autor:
Aksharkumar Dobariya, Tarek Y. El Ahmadieh, Levi B. Good, Ana G. Hernandez‑Reynoso, Vikram Jakkamsetti, Ronnie Brown, Misha Dunbar, Kan Ding, Jesus Luna, Raja Reddy Kallem, William C. Putnam, John M. Shelton, Bret M. Evers, Amirhossein Azami, Negar Geramifard, Stuart F. Cogan, Bruce Mickey, Juan M. Pascual
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
Externí odkaz:
https://doaj.org/article/8b912612aefa46f08bd6128ef9058503
Autor:
Isaac Marin-Valencia, Levi B. Good, Qian Ma, Joao Duarte, Teodoro Bottiglieri, Christopher M. Sinton, Charles W. Heilig, Juan M. Pascual
Publikováno v:
Neurobiology of Disease, Vol 48, Iss 1, Pp 92-101 (2012)
Brain glucose supplies most of the carbon required for acetyl-coenzyme A (acetyl-CoA) generation (an important step for myelin synthesis) and for neurotransmitter production via further metabolism of acetyl-CoA in the tricarboxylic acid (TCA) cycle.
Externí odkaz:
https://doaj.org/article/2058a68dd43e4b218da0f6dcad0555bf
Autor:
Gauri Kathote, Qian Ma, Gustavo Angulo, Hong Chen, Vikram Jakkamsetti, Aksharkumar Dobariya, Levi B. Good, Bruce Posner, Jason Y. Park, Juan M. Pascual
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 384:393-405
Autor:
Richard C Wang, Eunice E Lee, Nicole De Simone, Gauri Kathote, Sharon Primeaux, Adrian Avila, Dong-Min Yu, Mark Johnson, Levi B Good, Vikram Jakkamsetti, Ravi Sarode, Alice Ann Holland, Juan M Pascual
Publikováno v:
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
Red blood cells circulating through the brain are briefly but closely apposed to the capillary endothelium. We hypothesized that this contact provides a nearly direct pathway for metabolic substrate transfer to neural cells that complements the bette
Autor:
Karthik Rajasekaran, Qian Ma, Levi B. Good, Gauri Kathote, Vikram Jakkamsetti, Peiying Liu, Adrian Avila, Sharon Primeaux, Julio Enciso Alva, Kia H. Markussen, Isaac Marin-Valencia, Deepa Sirsi, Peter M. S. Hacker, Matthew S. Gentry, Jianzhong Su, Hanzhang Lu, Juan M. Pascual
Publikováno v:
Sci Transl Med
Individuals with glucose transporter type I deficiency (G1D) habitually experience nutrient-responsive epilepsy associated with decreased brain glucose. However, the mechanistic association between blood glucose concentration and brain excitability i
Publikováno v:
Communications in Nonlinear Science and Numerical Simulation. 56:330-343
This paper explores the internal dynamical mechanisms of epileptic seizures through quantitative modeling based on full brain electroencephalogram (EEG) signals. Our goal is to provide seizure prediction and facilitate treatment for epileptic patient