Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Levente Jozsef"'
Autor:
William C. Sessa, Levente Jozsef, Yunzhou Dong, Mohamed Bouaouina, Athanasia Skoura, David A. Calderwood, Monica Y. Lee, Takahisa Murata, Amelia K. Luciano, Pietro De Camilli, Satish Pasula, Eon Joo Park, Shawn M. Ferguson, Shira Landskroner-Eiger
Publikováno v:
Development. 141:1465-1472
Here we show that dynamin 2 (Dnm2) is essential for angiogenesis in vitro and in vivo. In cultured endothelial cells lacking Dnm2, vascular endothelial growth factor (VEGF) signaling and receptor levels are augmented whereas cell migration and morpho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::054d9c5fd693912a6453d9aa911b7424
https://doi.org/10.1242/dev.104539
https://doi.org/10.1242/dev.104539
Autor:
Levente Jozsef, Annarita Di Lorenzo, Carlos Fernández-Hernando, William C. Sessa, Deborah Jenkins
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 29:2033-2040
Objective— Deletion of Akt1 leads to severe atherosclerosis and occlusive coronary artery disease. Vascular smooth muscle cells (VSMCs) are an important component of atherosclerotic plaques, responsible for promoting plaque stability in advanced le
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::58d00ae722fe626636a7330da4f76298
https://doi.org/10.1161/atvbaha.109.196394
https://doi.org/10.1161/atvbaha.109.196394
Autor:
Wanling Pan, Driss El Kebir, Lili Wang, Charles N. Serhan, János G. Filep, Nicos A. Petasis, Levente Jozsef
Publikováno v:
American Journal of Respiratory and Critical Care Medicine. 180:311-319
Rationale: Apoptosis is essential for removal of neutrophils from inflamed tissues and efficient resolution of inflammation. Myeloperoxidase (MPO), abundantly expressed in neutrophils, not only generates cytotoxic oxidants but also signals through th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1451599a278f0c7349077dcfa01a337
https://doi.org/10.1164/rccm.200810-1601oc
https://doi.org/10.1164/rccm.200810-1601oc
Publikováno v:
The Journal of Immunology. 182:4386-4394
TLR9 detects bacterial DNA (CpG DNA) and elicits both innate and adoptive immunity. Recent evidence indicates that TLR9 is expressed in more diverse cell types than initially thought. In this study, we report that HUVECs constitutively express TLR9 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f4c62e6c6063f8046f6795b37d8912
https://doi.org/10.4049/jimmunol.0803044
https://doi.org/10.4049/jimmunol.0803044
Publikováno v:
Circulation Research. 103:352-359
Polymorphonuclear neutrophil granulocytes have a central role in innate immunity and their programmed cell death and removal are critical for efficient resolution of acute inflammation. Myeloperoxidase (MPO), a heme protein abundantly expressed in ne
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6da3bb13ad99a3e32095e4dd7d1eced5
https://doi.org/10.1161/01.res.0000326772.76822.7a
https://doi.org/10.1161/01.res.0000326772.76822.7a
Publikováno v:
Journal of Leukocyte Biology. 84:600-606
Neutrophils have a central role in innate immunity, and their programmed cell death and removal are critical to the optimal expression as well as to efficient resolution of inflammation. Human neutrophils express the pleiotropic receptor formyl pepti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e4de28a896213ff91a2714deba435a5
https://doi.org/10.1189/jlb.1107765
https://doi.org/10.1189/jlb.1107765
Publikováno v:
Archivum Immunologiae et Therapiae Experimentalis. 56:41-53
Neutrophils are essential for host defense and detect the presence of invading microorganisms through recognition of pathogen-associated molecular patterns. Among these receptors are Toll-like receptors (TLRs). Neutrophils express all known TLRs exce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88f74408c39c45d4f3a6f49ae8aaebb4
https://doi.org/10.1007/s00005-008-0008-3
https://doi.org/10.1007/s00005-008-0008-3
Autor:
Ethan P. Marin, Annarita Di Lorenzo, Heino Velazquez, Amelia K. Luciano, Leonard M. Milstone, William C. Sessa, Kara F. Held, Levente Jozsef, Jonathan Melendez
Objective— Palmitoylation, the reversible addition of the lipid palmitate to a cysteine, can alter protein localization, stability, and function. The ZDHHC family of protein acyl transferases catalyzes palmitoylation of numerous proteins. The role
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1466668d0250ec2a8bab57122111f98b
https://europepmc.org/articles/PMC4984414/
https://europepmc.org/articles/PMC4984414/
Publikováno v:
Cellular Signalling. 18:2302-2313
Neutrophils die rapidly via apoptosis and their survival is contingent upon rescue from constitutive programmed cell death by signals from the microenvironment. In these experiments, we investigated whether prevention of K + efflux could affect the a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d64171be4127c21233926b3b0749c63
https://doi.org/10.1016/j.cellsig.2006.05.013
https://doi.org/10.1016/j.cellsig.2006.05.013
Publikováno v:
The Journal of Immunology. 176:1195-1202
Bacterial DNA containing unmethylated CpG motifs is emerging as an important regulator of functions of human neutrophil granulocytes (polymorphonuclear leukocytes (PMN)). These motifs are recognized by TLR-9. Recent studies indicate that peroxynitrit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ba9f7757dea7650fd29ed3bce76da5b
https://doi.org/10.4049/jimmunol.176.2.1195
https://doi.org/10.4049/jimmunol.176.2.1195