Zobrazeno 1 - 10
of 93
pro vyhledávání: '"Levent M, Akyürek"'
Publikováno v:
Cells, Vol 13, Iss 16, p 1394 (2024)
Human cancers express altered levels of actin-binding cytoskeletal filamin A (FLNA) protein. FLNA in mammals consists of an actin-binding domain at its N-terminus that is followed by 24 immunoglobulin-like repeat modules interrupted by two hinge regi
Externí odkaz:
https://doaj.org/article/a2a035d5537446448acbc4c89ccdc26c
Autor:
Nikita Dutta, Anna Rohlin, Ella A. Eklund, Maria K. Magnusson, Frida Nilsson, Levent M. Akyürek, Per Torstensson, Volkan I. Sayin, Anna Lundgren, Andreas Hallqvist, Sukanya Raghavan
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
ObjectivesImmunotherapy by blocking programmed death protein-1 (PD-1) or programmed death protein-ligand1 (PD-L1) with antibodies (PD-1 blockade) has revolutionized treatment options for patients with non-small cell lung cancer (NSCLC). However, the
Externí odkaz:
https://doaj.org/article/ad6b94c7e52544b99cb293b558c87c00
Autor:
Petter Davik, Zuzana Chabadova, Martin Altreuther, Ingeborg Leinan, Sashidar Bandaru, Levent M. Akyürek, Erney Mattsson
Publikováno v:
EJVES Vascular Forum, Vol 49, Iss , Pp 23-29 (2020)
Objective: Current vascular grafts all have limitations. This study examined peritoneum as a potential graft material and the in vivo transfer of peritoneum into a functional artery like conduit after end to end anastomosis into the common carotid ar
Externí odkaz:
https://doaj.org/article/b363487daf154faabc357f5b0f9bf664
Autor:
Sashidar Bandaru, Chandu Ala, Matias Ekstrand, Murali K Akula, Matteo Pedrelli, Xi Liu, Göran Bergström, Liliana Håversen, Jan Borén, Martin O Bergo, Levent M Akyürek
Publikováno v:
PLoS ONE, Vol 15, Iss 9, p e0239284 (2020)
The Rho GTPase RAC1 is an important regulator of cytoskeletal dynamics, but the role of macrophage-specific RAC1 has not been explored during atherogenesis. We analyzed RAC1 expression in human carotid atherosclerotic plaques using immunofluorescence
Externí odkaz:
https://doaj.org/article/93032c03f95f4957805f132fd801d33f
Publikováno v:
Respiratory Medicine Case Reports, Vol 29, Iss , Pp - (2020)
Over 40 years ago, abnormal enlargement of the nucleus of tubular epithelial cells was reported in a rare distinct hereditary chronic interstitial nephritis, karyomegalic interstitial nephritis (KIN). Here, we report the second case of systemic karyo
Externí odkaz:
https://doaj.org/article/1d8435cbe0d047c5b18c0119c97a6147
Autor:
Zhiyuan V. Zou, Kristell Le Gal, Ahmed E. El Zowalaty, Lara E. Pehlivanoglu, Viktor Garellick, Nadia Gul, Mohamed X. Ibrahim, Per-Olof Bergh, Marcus Henricsson, Clotilde Wiel, Levent M. Akyürek, Martin O. Bergo, Volkan I. Sayin, Per Lindahl
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 241 (2021)
Dietary antioxidants and supplements are widely used to protect against cancer, even though it is now clear that antioxidants can promote tumor progression by helping cancer cells to overcome barriers of oxidative stress. Although recent studies have
Externí odkaz:
https://doaj.org/article/080aefb9e0cd473fb29d3da2d5029ec5
Publikováno v:
Journal of the European Academy of Dermatology and Venereology. 36:70-73
Basal cell carcinoma (BCC) may be challenging to differentiate from basaloid squamous cell carcinoma (bSCC), both clinically and histologically. BCC constitutes one of the most common tumours and metastatic behaviour is extremely rare. In contrast, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e216c3d524467ea610ed22088d9a7fbf
https://doi.org/10.1111/jdv.17530
https://doi.org/10.1111/jdv.17530
Autor:
Jan Borén, Levent M. Akyürek, Per Fogelstrand, Matias Ekstrand, Joakim Karlsson, Max Levin, Malin Levin, Keith E. Mostov, Lars Ny, Martin O. Bergo, Jonas Nilsson, Sara Bjursten, Zhiyuan Zhao, Kristell Le Gal, Andrew J. Ewald, Ankur Pandita
Publikováno v:
The American journal of pathology, vol 191, iss 11
Am J Pathol
Am J Pathol
Angiogenesis supplies oxygen and nutrients to growing tumors. Inhibiting angiogenesis may stop tumor growth, but vascular endothelial growth factor inhibitors have limited effect in most tumors. This limited effect may be explained by an additional,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d1eb09757032ec3e444706d55536daf
https://doi.org/10.1016/j.ajpath.2021.07.009
https://doi.org/10.1016/j.ajpath.2021.07.009
Autor:
Matias Ekstrand, Emma Widell, Anna Hammar, Levent M Akyürek, Martin Johansson, Björn Fagerberg, Göran Bergström, Malin C Levin, Per Fogelstrand, Jan Borén, Max Levin
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0178877 (2017)
OBJECTIVE:Severe hypoxia develops close to the necrotic core of advanced human atherosclerotic plaques, but the energy metabolic consequences of this hypoxia are not known. In animal models, plaque hypoxia is also associated with depletion of glucose
Externí odkaz:
https://doaj.org/article/f4e22ce7eebb469b82f241cfba854040
Autor:
Sashidar Bandaru, Bharat Prajapati, Prasanna Kumar Juvvuna, Sandor Dosa, Per Kogner, John I Johnsen, Chandrasekhar Kanduri, Levent M Akyürek
Publikováno v:
Neuro-oncology advances. 4(1)
Background The actin-binding protein filamin A (FLNA) regulates oncogenic signal transduction important for tumor growth, but the role of FLNA in the progression of neuroblastoma (NB) has not been explored. Methods We analyzed FLNA mRNA expression in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc3f7c5ae35c0d5aa558b317a6f68108
https://pubmed.ncbi.nlm.nih.gov/35441138
https://pubmed.ncbi.nlm.nih.gov/35441138