Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Levelle D Harris"'
Autor:
Jacob D Estes, Levelle D Harris, Nichole R Klatt, Brian Tabb, Stefania Pittaluga, Mirko Paiardini, G Robin Barclay, Jeremy Smedley, Rhonda Pung, Kenneth M Oliveira, Vanessa M Hirsch, Guido Silvestri, Daniel C Douek, Christopher J Miller, Ashley T Haase, Jeffrey Lifson, Jason M Brenchley
Publikováno v:
PLoS Pathogens, Vol 6, Iss 8, p e1001052 (2010)
The chronic phase of HIV infection is marked by pathological activation of the immune system, the extent of which better predicts disease progression than either plasma viral load or CD4(+) T cell count. Recently, translocation of microbial products
Externí odkaz:
https://doaj.org/article/b5191db7f6d542828d9bd9b2ceac4d03
Autor:
Levelle D. Harris, Jeremiah Khayumbi, Joshua Ongalo, Loren E. Sasser, Joan Tonui, Angela Campbell, Felix Hayara Odhiambo, Samuel Gurrion Ouma, Galit Alter, Neel R. Gandhi, Cheryl L. Day
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 10 (2020)
Mycobacterium tuberculosis (Mtb) is the causative agent of tuberculosis (TB), which leads to an estimated 1. 5 million deaths worldwide each year. Although the immune correlates of protection against Mtb infection and TB disease have not been well-de
Autor:
Michele van Rooyen, Willem A. Hanekom, Deborah Abrahams, Levelle D. Harris, Cheryl L. Day, Marwou de Kock, Lynnett Stone
Publikováno v:
The Journal of Immunology. 199:2069-2080
Coinfection with HIV is the single greatest risk factor for reactivation of latent Mycobacterium tuberculosis infection (LTBI) and progression to active tuberculosis disease. HIV-associated dysregulation of adaptive immunity by depletion of CD4 Th ce
Autor:
Cheryl L, Day, Deborah A, Abrahams, Levelle D, Harris, Michele, van Rooyen, Lynnett, Stone, Marwou, de Kock, Willem A, Hanekom
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 199(6)
Co-infection with HIV is the single greatest risk factor for reactivation of latent Mycobacterium tuberculosis infection (LTBI) and progression to active tuberculosis (TB) disease. HIV-associated dysregulation of adaptive immunity by depletion of CD4
Autor:
Nur Haq Alam, Stephen B. Calderwood, Jens Wrammert, Mohammad Rubel Hoq, Rie Nakajima, Firdausi Qadri, Rasheduzzaman Rashu, Meagan Kelly, Justin T. O’Neal, Pavol Kováč, Atiqur Rahman, Jason B. Harris, Edward T. Ryan, Siddhartha Kumar Bhaumik, Peng Xu, Algis Jasinskas, Leslie M. Mayo-Smith, Ashraful Islam Khan, Fahima Chowdhury, Taufiqur Rahman Bhuiyan, Emmanuel Y. Dotsey, Levelle D. Harris, Richelle C. Charles, Robert C. Kauffman, Phillip L. Felgner, Jessica F. Trost
Publikováno v:
mBio
mBio, vol 7, iss 6
mBio, Vol 7, Iss 6, p e02021-16 (2016)
mBio, Vol 7, Iss 6 (2016)
mBio, vol 7, iss 6
mBio, Vol 7, Iss 6, p e02021-16 (2016)
mBio, Vol 7, Iss 6 (2016)
We characterized the acute B cell response in adults with cholera by analyzing the repertoire, specificity, and functional characteristics of 138 monoclonal antibodies (MAbs) generated from single-cell-sorted plasmablasts. We found that the cholera-i
Autor:
Xiaoyong Sun, Li Pan, Levelle D. Harris, Nichole R. Klatt, Jacob D. Estes, John S. Barber, Carol L. Vinton, Que Dang, Vanessa M. Hirsch, Lauren A. Canary, Brian Tabb, Elias K. Haddad, Barbara Cervasi, Alexandra M. Ortiz, Yasmine Belkaid, Guido Silvestri, Lauren K. Yokomizo, Jason M. Brenchley, Joshua D. Milner, Galit Alter, Mirko Paiardini, Jeffrey D. Lifson
Publikováno v:
Mucosal Immunology. 5:646-657
Human immunodeficiency virus (HIV) and Simian immunodeficiency virus (SIV) disease progression is associated with multifocal damage to the gastrointestinal tract epithelial barrier that correlates with microbial translocation and persistent pathologi
Autor:
Jeremy Smedley, Mirko Paiardini, Levelle D. Harris, Rhonda MacAllister, Charles M. Trubey, W. Gregory Alvord, Jeffrey D. Lifson, Octavio A. Quiñones, David R. Morcock, Jacob D. Estes, Michael Piatak, Brian Tabb, Xing Pei Hao, Guido Silvestri, Jason M. Brenchley
Publikováno v:
The Journal of Infectious Diseases. 207:880-892
(See the editorial commentary by Michael on pages 875–6.) Persistent immune activation is a hallmark of human immunodeficiency virus type 1 (HIV-1) infection in humans and simian immunodeficiency virus (SIV) infection in rhesus macaques. In progres
Autor:
Jason M. Brenchley, Ivona Pandrea, Vanessa M. Hirsch, Levelle D. Harris, Carol L. Vinton, Nichole R. Klatt, Judith A. Briant, Ruth A. Woodward, Guido Silvestri, Richard Herbert, Cristian Apetrei, Brigitte E. Sanders-Beer
Publikováno v:
Journal of Virology. 85:8702-8708
Many species of African nonhuman primates are natural hosts for individual strains of simian immunodeficiency virus (SIV). These infected animals do not, however, develop AIDS. Here we show that multiple species of African nonhuman primate species ch
Autor:
Jeffrey D. Lifson, Carol L. Vinton, Judith A. Briant, Vanessa M. Hirsch, David Price, Kristin Ladell, Jason M. Brenchley, Levelle D. Harris, Jacob D. Estes, Brian Tabb, Nichole R. Klatt
Publikováno v:
Blood. 116:4148-4157
T cells that express the γδ T-cell receptor, which recognize microbial or stress-induced antigens, represent a minority of blood T cells but constitute a major proportion of intraepithelial lymphocytes in the gastrointestinal mucosa. As microbial p
Autor:
Jason M. Brenchley, Michaela Müller-Trutwin, Jacob D. Estes, Guido Silvestri, Cristian Apetrei, Mirko Paiardini, Jeffrey D. Lifson, Vanessa M. Hirsch, Donald L. Sodora, Brian Tabb, Ivona Vasile-Pandrea, Levelle D. Harris, Nichole R. Klatt, Daniel C. Douek
Publikováno v:
Journal of Virology
Journal of Virology, 2010, 84 (15), pp.7886-7891. ⟨10.1128/jvi.02612-09⟩
Journal of Virology, American Society for Microbiology, 2010, 84 (15), pp.7886-7891. ⟨10.1128/jvi.02612-09⟩
Journal of Virology, 2010, 84 (15), pp.7886-7891. ⟨10.1128/jvi.02612-09⟩
Journal of Virology, American Society for Microbiology, 2010, 84 (15), pp.7886-7891. ⟨10.1128/jvi.02612-09⟩
The mechanisms underlying the AIDS resistance of natural hosts for simian immunodeficiency virus (SIV) remain unknown. Recently, it was proposed that natural SIV hosts avoid disease because their plasmacytoid dendritic cells (pDCs) are intrinsically