Gene utility recapitulates chromosomal aberrancies in advanced stage neuroblastoma.

Autor: Ung CY; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA., Levee TM; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA., Zhang C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA., Correia C; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA., Yeo KS; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA., Li H; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA., Zhu S; Department of Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic College of Medicine, Rochester, MN 55905, USA.; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Rochester, MN 55902, USA.

Publikováno v: Computational and structural biotechnology journal [Comput Struct Biotechnol J] 2022 Jun 20; Vol. 20, pp. 3291-3303. Date of Electronic Publication: 2022 Jun 20 (Print Publication: 2022).

GAS7 Deficiency Promotes Metastasis in MYCN-Driven Neuroblastoma.

Autor: Dong Z; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Yeo KS; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Lopez G; Department of Genetics and Genomic Sciences and Icahn Institute for Data Science and Genomic Technology, Icahn School of Medicine at Mount Sinai, New York, New York., Zhang C; Department of Molecular Pharmacology & Experimental Therapeutics, Center for Individualized Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota., Dankert Eggum EN; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Rokita JL; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Division of Neurosurgery, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Ung CY; Department of Molecular Pharmacology & Experimental Therapeutics, Center for Individualized Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota., Levee TM; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Her ZP; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Howe CJ; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Hou X; Departments of Oncology, Radiation Oncology, and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota., van Ree JH; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Li S; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., He S; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., Tao T; Children's Hospital, Zhejiang University School of Medicine; National Clinical Research Center for Child Health, National Children's Regional Medical Center, Hangzhou, China., Fritchie K; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Torres-Mora J; Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota., Lehman JS; Department of Dermatology, Mayo Clinic, Rochester, Minnesota., Meves A; Department of Dermatology, Mayo Clinic, Rochester, Minnesota., Razidlo GL; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Rathi KS; Center for Data-Driven Discovery in Biomedicine, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania., Weroha SJ; Departments of Oncology, Radiation Oncology, and Molecular Pharmacology and Experimental Therapeutics, Mayo Clinic, Rochester, Minnesota., Look AT; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts., van Deursen JM; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota., Li H; Department of Molecular Pharmacology & Experimental Therapeutics, Center for Individualized Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota., Westendorf JJ; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota.; Department of Orthopedic Surgery, Mayo Clinic, Rochester, Minnesota., Maris JM; Department of Bioinformatics and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.; Abramson Family Cancer Research Institute, Philadelphia, Pennsylvania., Zhu S; Department of Biochemistry and Molecular Biology, Mayo Clinic College of Medicine, Mayo Clinic Cancer Center, Rochester, Minnesota. Zhu.shizhen@mayo.edu.; Department of Molecular Pharmacology & Experimental Therapeutics, Center for Individualized Medicine, Mayo Clinic College of Medicine, Rochester, Minnesota.

Publikováno v: Cancer research [Cancer Res] 2021 Jun 01; Vol. 81 (11), pp. 2995-3007. Date of Electronic Publication: 2021 Feb 18.

MTOR promotes basal cell carcinoma growth through atypical PKC.

Autor: Chow RY; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Levee TM; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Kaur G; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Cedeno DP; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Doan LT; Department of Dermatology, University of California, Irvine, CA, USA., Atwood SX; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA.; Department of Dermatology, University of California, Irvine, CA, USA.; Chao Family Comprehensive Cancer Center, University of California, Irvine, CA, USA.

Publikováno v: Experimental dermatology [Exp Dermatol] 2021 Mar; Vol. 30 (3), pp. 358-366. Date of Electronic Publication: 2020 Dec 20.