Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Lev Y. Yampolsky"'
Autor:
Meijiang Gao, Marina Veil, Marcus Rosenblatt, Aileen Julia Riesle, Anna Gebhard, Helge Hass, Lenka Buryanova, Lev Y. Yampolsky, Björn Grüning, Sergey V. Ulianov, Jens Timmer, Daria Onichtchouk
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-19 (2022)
Zygotic genome activation in zebrafish relies on pluripotency transcription factors Pou5f3 and Sox19b. Here the authors investigate how these factors interact in vivo by analyzing the changes in chromatin state and time-resolved transcription in Pou5
Externí odkaz:
https://doaj.org/article/57468c6712aa486fa489733db381cf36
Publikováno v:
Ecology and Evolution, Vol 12, Iss 10, Pp n/a-n/a (2022)
Abstract Hypoxia has profound and diverse effects on aerobic organisms, disrupting oxidative phosphorylation and activating several protective pathways. Predictions have been made that exposure to mild intermittent hypoxia may be protective against m
Externí odkaz:
https://doaj.org/article/2d80cd71a31e4b47a8e29e5af9f07b3d
Publikováno v:
Journal of Great Lakes Research. 48:1219-1229
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f94d609e604110bba4697a5745a37fda
https://doi.org/10.1016/j.jglr.2022.07.006
https://doi.org/10.1016/j.jglr.2022.07.006
Publikováno v:
Oecologia.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1443c9cfbf63ef3e476a3d61d385af2b
https://doi.org/10.1007/s00442-023-05382-1
https://doi.org/10.1007/s00442-023-05382-1
Autor:
Lev Y. Yampolsky, Yongmin Cho, Marc W. Kirschner, Cora E. Anderson, Millicent N. Ekwudo, Leonid Peshkin, Rachael A Jonas-Closs
Publikováno v:
Biogerontology. 23:85-97
Aging is a multifaceted process of accumulation of damages and waste in cells and tissues; age-related changes in mitochondria and in respiratory metabolism have been in the focus of aging research for decades. Here we investigated age-related change
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10d96725115d15b572893df7b9dfb256
https://doi.org/10.1007/s10522-021-09947-6
https://doi.org/10.1007/s10522-021-09947-6
Autor:
Cora E. Anderson, Morad C. Malek, Rachael A. Jonas-Closs, Yongmin Cho, Leonid Peshkin, Marc W. Kirschner, Lev Y. Yampolsky
Publikováno v:
The American naturalist. 200(5)
Maternal age effects on offspring life history are known in a variety of organisms, with offspring of older mothers typically having lower life expectancy (the Lansing effect). However, there is no consensus on the generality and mechanisms of this p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9020f0973d43abf757b0213b5afe1276
https://pubmed.ncbi.nlm.nih.gov/36260845
https://pubmed.ncbi.nlm.nih.gov/36260845
The dietary supply with polyunsaturated fatty acids (PUFA) crucially affects animals’ performance at different temperatures. However, the underlying physiological mechanisms are still insufficiently understood. Here, we analyzed lifespan and heat t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82964e1199e96f2836fd977e02df9f33
https://doi.org/10.21203/rs.3.rs-2015531/v1
https://doi.org/10.21203/rs.3.rs-2015531/v1
Autor:
Maike Herrmann, Lev Y. Yampolsky
Publikováno v:
Genetica. 149:143-153
Genome-wide studies are prone to false positives due to inherently low priors and statistical power. One approach to ameliorate this problem is to seek validation of reported candidate genes across independent studies: genes with repeatedly discovere
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7950d52b4130124f16384fa86f9fa024
https://doi.org/10.1007/s10709-021-00122-w
https://doi.org/10.1007/s10709-021-00122-w
Hypoxia has profound and diverse effects on aerobic organisms, disrupting oxidative phosphorylation and activating several protective pathways. Predictions have been made that exposure to mild intermittent hypoxia may be protective against more sever
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6bc19a55db28299002849b478588d857
https://doi.org/10.1101/2022.03.13.484120
https://doi.org/10.1101/2022.03.13.484120
Publikováno v:
Aging Cell. 21
We present a novel platform for testing the effects of interventions on the life- and healthspan of a short-lived freshwater organism with complex behavior and physiology-the planktonic crustacean Daphnia magna. Within this platform, dozens of comple
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c06e44e25f16c3fc9dd08f36e258229
https://doi.org/10.1111/acel.13571
https://doi.org/10.1111/acel.13571