Zobrazeno 1 - 10
of 207
pro vyhledávání: '"Lev S Tsimring"'
Autor:
Julie Paxman, Zhen Zhou, Richard O'Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Publikováno v:
eLife, Vol 11 (2022)
Chromatin instability and protein homeostasis (proteostasis) stress are two well-established hallmarks of aging, which have been considered largely independent of each other. Using microfluidics and single-cell imaging approaches, we observed that, d
Externí odkaz:
https://doaj.org/article/8b123c5e430f4c03951e121b50a9be75
Autor:
Natalie A Cookson, William H Mather, Tal Danino, Octavio Mondragón‐Palomino, Ruth J Williams, Lev S Tsimring, Jeff Hasty
Publikováno v:
Molecular Systems Biology, Vol 7, Iss 1, Pp 1-9 (2011)
Abstract High‐throughput technologies have led to the generation of complex wiring diagrams as a post‐sequencing paradigm for depicting the interactions between vast and diverse cellular species. While these diagrams are useful for analyzing biol
Externí odkaz:
https://doaj.org/article/7509c9323d874f10a48122a309c2e61e
Autor:
Diane M Longo, Jangir Selimkhanov, Jeffrey D Kearns, Jeff Hasty, Alexander Hoffmann, Lev S Tsimring
Publikováno v:
PLoS Computational Biology, Vol 9, Iss 6, p e1003112 (2013)
Many cellular stress-responsive signaling systems exhibit highly dynamic behavior with oscillatory features mediated by delayed negative feedback loops. What remains unclear is whether oscillatory behavior is the basis for a signaling code based on f
Externí odkaz:
https://doaj.org/article/d46deef5c1d24267890fa77561ef3eea
Publikováno v:
New Journal of Physics, Vol 15, Iss 3, p 035029 (2013)
In this paper we develop a continuum theory of clustering in ensembles of self-propelled inelastically colliding rods with applications to collective dynamics of common gliding bacteria Myxococcus xanthus . A multi-phase hydrodynamic model that coupl
Externí odkaz:
https://doaj.org/article/6f93938b2c194be9b9f4b9dc8b1d681f
Autor:
Zhen Zhou, Yuting Liu, Yushen Feng, Stephen Klepin, Lev S. Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Publikováno v:
Science. 380:376-381
Synthetic biology enables the design of gene networks to confer specific biological functions, yet it remains a challenge to rationally engineer a biological trait as complex as longevity. A naturally occurring toggle switch underlies fate decisions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9edd23ea5a6c76bfdc9b5a0b8388320f
https://doi.org/10.1126/science.add7631
https://doi.org/10.1126/science.add7631
Macrophages must respond appropriately to pathogens and other pro-inflammatory stimuli in order to perform their roles in fighting infection. One way in which inflammatory stimuli can vary is in their dynamics – that is, the amplitude and duration
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::51b79dab3c3f89bc7785888443b6b0e6
https://doi.org/10.1101/2023.05.19.541501
https://doi.org/10.1101/2023.05.19.541501
Autor:
Zhen Zhou, Julie Paxman, Richard O'Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Chromatin instability and protein homeostasis (proteostasis) stress are two well-established hallmarks of aging, which have been considered largely independent of each other. Using microfluidics and single-cell imaging approaches, we observed that, d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7390565de28c9cee00d7665579630c10
https://escholarship.org/uc/item/96h8k9h8
https://escholarship.org/uc/item/96h8k9h8
Autor:
Zhen Zhou, Julie Paxman, Richard O'Laughlin, Yuting Liu, Yang Li, Wanying Tian, Hetian Su, Yanfei Jiang, Shayna E Holness, Elizabeth Stasiowski, Lev S Tsimring, Lorraine Pillus, Jeff Hasty, Nan Hao
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5af0cacc07463f14d0a9e1f9180db9b
https://doi.org/10.7554/elife.75978.sa2
https://doi.org/10.7554/elife.75978.sa2
Autor:
Arkady Pikovsky, Lev S. Tsimring
Publikováno v:
Mathematical Biosciences. 358:108980
Asymmetric damage segregation (ADS) is ubiquitous among unicellular organisms: After a mother cell divides, its two daughter cells receive sometimes slightly, sometimes strongly different fractions of damaged proteins accumulated in the mother cell.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9bd01e3c35194b4af48a1ce11ab7d07b
https://doi.org/10.1016/j.mbs.2023.108980
https://doi.org/10.1016/j.mbs.2023.108980
Publikováno v:
Biophysical journal. 121(21)
Cellular responses to the presence of toxic compounds in their environment require prompt expression of the correct levels of the appropriate enzymes, which are typically regulated by transcription factors that control gene expression for the duratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::446d047954a1eeb22a298e72f939f4af
https://pubmed.ncbi.nlm.nih.gov/36168291
https://pubmed.ncbi.nlm.nih.gov/36168291