Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Lev N Porokhovnik"'
Autor:
Elizaveta S. Ershova, Ekaterina A. Savinova, Larisa V. Kameneva, Lev N. Porokhovnik, Roman V. Veiko, Tatiana A. Salimova, Vera L. Izhevskaya, Sergei I. Kutsev, Natalia N.Veiko, Svetlana V. Kostyuk
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 8, p 191 (2023)
Background: The chromosome 1q12 region harbors the genome’s largest pericentromeric heterochromatin domain that includes tandemly repeated satellite III DNA [SatIII (1)]. Increased SatIII (1) copy numbers have been found in cultured human skin fibr
Externí odkaz:
https://doaj.org/article/790c0799b759468b8ed35e91c6f61f2a
Autor:
Galina V. Shmarina, Elizaveta S. Ershova, Natalia V. Simashkova, Svetlana G. Nikitina, Julia M. Chudakova, Natalia N. Veiko, Lev N. Porokhovnik, Anna Y. Basova, Antonina F. Shaposhnikova, Daria A. Pukhalskaya, Vladimir M. Pisarev, Natalia J. Korovina, Natalia L. Gorbachevskaya, Olga A. Dolgikh, Marina Bogush, Sergey I. Kutsev, Svetlana V. Kostyuk
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Abstract Background Autism spectrum disorders (ASD) are known to be associated with an inflammatory process related to immune system dysfunction. This study’s aim was to investigate the role of cell-free DNA in chronic inflammatory process in ASD p
Externí odkaz:
https://doaj.org/article/8322e59576454d729c84d83b531256f9
Autor:
Kostyuk, Elizaveta S. Ershova, Ekaterina A. Savinova, Larisa V. Kameneva, Lev N. Porokhovnik, Roman V. Veiko, Tatiana A. Salimova, Vera L. Izhevskaya, Sergey I. Kutsev, Natalia N. Veiko, Svetlana V.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 14; Pages: 11283
The fragment of satellite III (f-SatIII) is located in pericentromeric heterochromatin of chromosome 1. Cell with an enlarged f-SatIII block does not respond to various stimuli and are highly stress-susceptible. The fraction of f-SatIII in the cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::11d56d8edf0a7dccbd64a8989c1d25d5
Autor:
Elena M. Malinovskaya, Elizaveta S. Ershova, Natalya A. Okorokova, Vladimir P. Veiko, Marina S. Konkova, Ekaterina A. Kozhina, Ekaterina A. Savinova, Lev N. Porokhovnik, Serguey I. Kutsev, Nataly N. Veiko, Svetlana V. Kostyuk
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Introduction: The cell free ribosomal DNA (cf-rDNA) is accrued in the total pool of cell free DNA (cfDNA) in some non-cancer diseases and demonstrates DAMPs characteristics. The major research questions: (1) How does cell free rDNA content change in
Externí odkaz:
https://doaj.org/article/3b6b0097252e4e42be63e8e9310314d7
Autor:
Elena M. Malinovskaya, Elizaveta S. Ershova, Vera E. Golimbet, Lev N. Porokhovnik, Nataliya A. Lyapunova, Serguey I. Kutsev, Natalia N. Veiko, Svetlana V. Kostyuk
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Introduction: The multi-copied genes coding for the human 18, 5.8, and 28S ribosomal RNA (rRNA) are located in five pairs of acrocentric chromosomes forming so-called rDNA. Human genome contains unmethylated, slightly methylated, and hypermethylated
Externí odkaz:
https://doaj.org/article/7ce24087432c4ef89853860ffa0d6284
Autor:
Svetlana V. Kostyuk, Elizaveta S. Ershova, Andrey V. Martynov, Andrey V. Artyushin, Lev N. Porokhovnik, Elena M. Malinovskaya, Elizaveta M. Jestkova, Natalia V. Zakharova, George P. Kostyuk, Vera L. Izhevskaia, Sergey I. Kutsev, Natalia N. Veiko
Publikováno v:
Genes; Volume 13; Issue 12; Pages: 2283
Oxidized in vitro genomic DNA (gDNA) is known to launch an adaptive response in human cell cultures. The cfDNA extracted from the plasma of schizophrenic patients (sz-cfDNA) and healthy controls (hc-cfDNA) contains increased amounts of 8-oxodG, a DNA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151f92403eb529a616fc639ad3c620fd
Autor:
Lev N. Porokhovnik, Vladimir M. Pisarev, Anastasia G. Chumachenko, Julia M. Chudakova, Elizaveta S. Ershova, Natalia N. Veiko, Natalia L. Gorbachevskaya, Uliana A. Mamokhina, Alexander B. Sorokin, Anna Ya. Basova, Mikhail S. Lapshin, Vera L. L. Izhevskaya, Svetlana V. Kostyuk
Publikováno v:
Genes; Volume 14; Issue 3; Pages: 718
Increased oxidative/genotoxic stress is known to impact the pathophysiology of ASD (autism spectrum disorder). Clinical studies, however, reported limited, heterogeneous but promising responses to treatment with antioxidant remedies. We determined wh
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d12ffd6cd947e36d4b636fb7afb4d27
https://doi.org/10.3390/genes14030718
https://doi.org/10.3390/genes14030718
Autor:
Elizaveta S. Ershova, Natalia N. Veiko, Svetlana G. Nikitina, Elena E. Balakireva, Andrey V. Martynov, Julia M. Chudakova, Galina V. Shmarina, Svetlana E. Kostyuk, Nataliya A. Salimova, Roman V. Veiko, Lev N. Porokhovnik, Aliy Yu Asanov, Vera L. Izhevskaia, Sergey I. Kutsev, Nataliya V. Simashkova, Svetlana V. Kostyuk
Publikováno v:
Journal of Personalized Medicine; Volume 12; Issue 11; Pages: 1796
Introduction: Differential diagnostics of early-onset schizophrenia and autism spectrum disorders (ASD) are a problem of child psychiatry. The prognosis and relevant treatment are to a large degree determined by the correctness of diagnosis. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9e46e7d55d5dbdea2a10caad90b820f
https://doi.org/10.3390/jpm12111796
https://doi.org/10.3390/jpm12111796
Publikováno v:
Genes, Vol 12, Iss 1524, p 1524 (2021)
Genes
Genes
The pericentric satellite III (SatIII or Sat3) and II tandem repeats recently appeared to be transcribed under stress conditions, and the transcripts were shown to play an essential role in the universal stress response. In this paper, we review the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c7998da433ee420c7d82df1251e72a1
https://www.mdpi.com/2073-4425/12/10/1524
https://www.mdpi.com/2073-4425/12/10/1524
Autor:
Natalia V. Simashkova, Antonina F. Shaposhnikova, Anna Y. Basova, Vladimir M. Pisarev, S. V. Kostyuk, Natalia L. Gorbachevskaya, Galina Shmarina, Olga A. Dolgikh, Elizaveta S. Ershova, Natalia N. Veiko, Daria Pukhalskaya, Svetlana G. Nikitina, Julia M. Chudakova, Lev N. Porokhovnik, Marina Bogush, Natalia J. Korovina, Sergey I. Kutsev
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-13 (2020)
Journal of Neuroinflammation
Journal of Neuroinflammation
Background Autism spectrum disorders (ASD) are known to be associated with an inflammatory process related to immune system dysfunction. This study’s aim was to investigate the role of cell-free DNA in chronic inflammatory process in ASD patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7cce3de389b6f404ffb7e70ff4f1482
https://doi.org/10.1186/s12974-020-01881-7
https://doi.org/10.1186/s12974-020-01881-7