Zobrazeno 1 - 10 of 77 pro vyhledávání: '"Leusink, M."'
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Akademický článek
PO-1724 Reducing the number of incidents that occur during patient treatment
Autor: Pasma, K., Meerveld, R., Barnhoorn, J., Leusink, M.
Publikováno v: In Radiotherapy and Oncology August 2021 161 Supplement 1:S1449-S1450
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Cholesteryl Ester Transfer Protein Polymorphisms, Statin Use, and Their Impact on Cholesterol Levels and Cardiovascular Events
Autor: André, Romain, Elbaz, Meyer, Khalife, Khalife, Lim, Pascal, Ennezat, Pierre-Vladimir, Coste, Pierre, Le Breton, Hervé, Bataille, Vincent, Ferrières, Jean, Leusink, M, Onland-Moret, N, Asselbergs, F, Ding, B, Kotti, S, van Zuydam, N, Papp, A, Danchin, Nicolas, Donnelly, L, Morris, A, Chasman, D, Doevendans, P, Klungel, O, Ridker, P, van Gilst, W, Simon, Tabassome, Nyberg, F, Palmer, C, Sadee, W, van Der Harst, P, de Bakker, P, de Boer, A, Verstuyft, C, Maitland-van Der Zee, A
Publikováno v: Clinical Pharmacology & Therapeutics, 95(3), 314-320. Nature Publishing Group
Clinical Pharmacology and Therapeutics
Clinical Pharmacology and Therapeutics, 2013, 95 (2), pp.314-320. ⟨10.1038/clpt.2013.194⟩
Clinical Pharmacology and Therapeutics, American Society for Clinical Pharmacology and Therapeutics, 2013, 95 (2), pp.314-320. ⟨10.1038/clpt.2013.194⟩
The association of nonfunctional variants of the cholesteryl ester transfer protein (CETP) with efficacy of statins has been a subject of debate. We evaluated whether three functional CETP variants influence statin efficacy. The effect of CETP genoty
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b506750d275a06613213d70721bc6ea2
https://research.rug.nl/en/publications/5a3ef928-2c6d-4690-8431-8458826c1ee4
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5
Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis
Autor: Nuesch, E., Dale, C., Palmer, T.M., White, J., Keating, B.J., van Iperen, E.P., Goel, A., Padmanabhan, S., Asselbergs, F.W., Verschuren, W., Wijmenga, C., Van der Schouw, Y., Onland-Moret, N., Lange, L.A., Hovingh, G., Sivapalaratnam, S., Morris, R.W., Whincup, P.H., Wannamethe, G.S., Gaunt, T.R., Ebrahim, S., Steel, L., Nair, N., Reiner, A.P., Kooperberg, C., Wilson, J.F., Bolton, J.L., McLachlan, S., Price, J.F., Strachan, M.W., Robertson, C.M., Kleber, M.E., Delgado, G., Marz, W., Melander, O., Dominiczak, A.F., Farrall, M., Watkins, H., Leusink, M., Maitland-van der Zee, A.H., de Groot, M.C., Dudbridge, F., Hingorani, A., Ben-Shlomo, Y., Lawlor, D.A., Amuzu, A., Caufield, M., Cavadino, A., Cooper, J., Davies, T., Drenos, F., Engmann, J., Finan, C., Giambartolomei, C., Hardy, R., Humphries, S., Hypponen, E., Kivimaki, M., Kuh, D., Kumari, M., Ong, K., Plagnol, V., Power, C., Richards, M., Shah, S., Shah, T., Sofat, R., Talmud, P., Wareham, N., Warren, H., Whittaker, J., Wong, A., Zabaneh, D., Davey Smith, G., Wells, J.C., Leon, D.A., Holmes, M.V., Casas, J.P.
Publikováno v: International Journal of Epidemiology
Background: We investigated causal effect of completed growth, measured by adult height, on coronary heart disease (CHD), stroke and cardiovascular traits, using instrumental variable (IV) Mendelian randomization meta-analysis.\ud \ud Methods: We dev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5f8a8f6caef3d7a12dcefd5a349c1104
https://eprints.gla.ac.uk/107205/1/107205.pdf
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6
Challenges and opportunities in pharmacogenomics: studies in cardiovascular disease and asthma
Autor: Leusink, M.
A drug that is effective in one group of patients may have a reduced or no effect in other patients. Similarly, the risk for side effects differs between patients. The discipline of pharmacogenomics studies how genetic variation in the population can
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______101::5209da29e6fde0296275d7bdd50cc66a
https://dspace.library.uu.nl/handle/1874/308496
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7
HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials
Autor: Swerdlow, DI, Preiss, D, Kuchenbaecker, KB, Holmes, MV, Engmann, JEL, Shah, T, Sofat, R, Stender, S, Johnson, PCD, Scott, RA, Leusink, M, Verweij, N, Sharp, SJ, Guo, Y, Giambartolomei, C, Chung, C, Peasey, A, Amuzu, A, Li, K, Palmen, J, Howard, P, Cooper, JA, Drenos, F, Li, YR, Lowe, G, Gallacher, J, Stewart, MCW, Tzoulaki, I, Buxbaum, SG, Van Der A, DL, Forouhi, NG, Onland-Moret, NC, Van Der Schouw, YT, Schnabel, RB, Hubacek, JA, Kubinova, R, Baceviciene, M, Tamosiunas, A, Pajak, A, Topor-Madry, R, Stepaniak, U, Malyutina, S, Baldassarre, D, Sennblad, B, Tremoli, E, De Faire, U, Veglia, F, Ford, I, Jukema, JW, Westendorp, RGJ, De Borst, GJ, De Jong, PA, Algra, A, Spiering, W, Der Zee, AHMV, Klungel, OH, De Boer, A, Doevendans, PA, Eaton, CB, Robinson, JG, Duggan, D, Kjekshus, J, Downs, JR, Gotto, AM, Keech, AC, Marchioli, R, Tognoni, G, Sever, PS, Poulter, NR, Waters, DD, Pedersen, TR, Amarenco, P, Nakamura, H, McMurray, JJV, Lewsey, JD, Chasman, DI, Ridker, PM, Maggioni, AP, Tavazzi, L, Ray, KK, Seshasai, SRK, Manson, JE, Price, JF, Whincup, PH, Morris, RW, Lawlor, DA
Publikováno v: Swerdlow, DI; Preiss, D; Kuchenbaecker, KB; Holmes, MV; Engmann, JEL; Shah, T; et al.(2015). HMG-coenzyme A reductase inhibition, type 2 diabetes, and bodyweight: Evidence from genetic analysis and randomised trials. The Lancet, 385(9965), 351-361. doi: 10.1016/S0140-6736(14)61183-1. UCSF: Retrieved from: http://www.escholarship.org/uc/item/3c9569hs
© 2015 Swerdlow et al. Open Access article distributed under the terms of CC BY. Background Statins increase the risk of new-onset type 2 diabetes mellitus. We aimed to assess whether this increase in risk is a consequence of inhibition of 3-hydroxy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od_______325::93d969557b1276f6c8f9ebd9b77f240d
http://www.escholarship.org/uc/item/3c9569hs
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8
Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data
Autor: Holmes, MV, Dale, CE, Zuccolo, L, Silverwood, RJ, Guo, Y, Ye, Z, Prieto-Merino, D, Dehghan, Abbas, Trompet, S, Wong, A, Cavadino, A, Drogan, D, Padmanabhan, S, Li, Shan, Yesupriya, A, Leusink, M, Sundstrom, J, Hubacek, JA, Pikhart, H, Swerdlow, DI, Panayiotou, AG, Borinskaya, SA, Finan, C, Shah, S, Kuchenbaecker, KB, Shah, T, Engmann, J, Folkersen, L, Eriksson, P, Ricceri, F, Melander, O, Sacerdote, C, Gamble, DM, Rayaprolu, S, Ross, OA, McLachlan, S, Vikhireva, O, Sluijs, Iris, Scott, RA, Adamkova, V, Flicker, L, van Bockxmeer, FM, Power, C, Marques-Vidal, P, Meade, T, Marmot, MG, Ferro, JM, Paulos-Pinheiro, S, Humphries, SE, Talmud, PJ, Leach, IM, Verweij, N (Niek), Linneberg, A, Skaaby, T, Doevendans, PA, Cramer, MJ, van der Harst, P, Klungel, OH, Dowling, NF, Dominiczak, AF, Kumari, M, Nicolaides, AN, Weikert, C, Boeing, H, Ebrahim, S, Gaunt, TR, Price, JF, Lannfelt, L, Peasey, A, Kubinova, R, Pajak, A, Malyutina, S, Voevoda, MI, Tamosiunas, A, Zee, AH, Norman, PE, Hankey, GJ, Bergmann, MM, Hofman, Bert, Franco Duran, OH, Cooper, J, Palmen, J, Spiering, W, Jong, PA, Kuh, D, Hardy, R, Uitterlinden, André, Ikram, Arfan, Ford, I, Hyppoenen, E, Almeida, OP, Wareham, NJ, Khaw, KT, Hamsten, A, Husemoen, LLN, Tjonneland, A, Tolstrup, JS, Rimm, E, Beulens, JWJ, Verschuren, WMM, Onland-Moret, NC, Hofker, MH, Wannamethee, SG, Whincup, PH, Morris, R, Vicente, AM, Watkins, H, Farrall, M, Jukema, JW, Meschia, J, Cupples, LA, Sharp, SJ, Fornage, M, Kooperberg, C, Lacroix, AZ, Dai, JY, Lanktree, MB, Siscovick, DS, Jorgenson, E, Spring, B, Coresh, J, Li, YR, Buxbaum, SG, Schreiner, PJ, Ellison, RC, Tsai, MY, Patel, SR, Redline, S, Johnson, AD, Hoogeveen, RC, Rotter, JI, Boerwinkle, E, de Bakker, PIW, Kivimaki, M, Asselbergs, FW, Sattar, N, Lawlor, DA, Whittaker, J, Smith, GD, Mukamal, K, Psaty, BM, Wilson, JG, Lange, LA, Hamidovic, A, Hingorani, AD, Nordestgaard, BG, Bobak, M, Leon, DA, Langenberg, C, Palmer, TM, Reiner, AP, Keating, BJ, Dudbridge, F, Casas, JP
Publikováno v: BMJ-British medical journal, 349. BMJ Publishing Group
Objective: To use the rs1229984 variant in the alcohol dehydrogenase 1B gene (ADH1B) as an instrument to investigate the causal role of alcohol in cardiovascular disease. Design: Mendelian randomisation meta-analysis of 56 epidemiological studies. Pa
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::9bce34c69de0a3c4e83beb0ae8fc1f79
https://hdl.handle.net/20.500.14279/3672
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9
Secretory phospholipase A2-IIA and cardiovascular disease: a mendelian randomization study
Autor: Holmes, M.V., Simon, T., Exeter, H.J, Folkersen, L., Asselbergs, F.W., Guardiola, M., Cooper, J.A., Palmen, J., Hubacek, J.A., Carruthers, K.F., Horne, B.D., Brunisholz, K.D., Mega, J.L., Van Iperen, E.P., Li, M., Leusink, M., Trompet, S., Verschuren, J.J., Hovingh, G.K., Dehghan, A., Nelson, C.P., Kotti, S., Danchin, N., Scholz, M., Haase, C.L., Rothenbacher, D., Swerdlow, D.I., Kuchenbaecker, K.B., Staines-Urias, E., Goel, A., Van 't Hooft, F., Gertow, K., De Faire, U., Panayiotou, A.G., Tremoli, E., Baldassarre, D., Veglia, F., Holdt, L.M., Beutner, F., Gansevoort. R.T., Navis, G.J., Mateo, L.I., Breitling, L.P., Brenner, H., Thiery, J., Dallmeier, D., Franco-Cereceda, A., Boer, J.M., Stephens, J.W., Hofker, M.H., Tedgui, A., Hofman, A., Uitterlinden, A.G., Adamkova, V., Pitha, J., Onland-Moret, N.C., Cramer, M.J., Nathoe, H.M., Spiering, W., Klungel, O.H., Kumari, M., Whincup, P.H., Morrow, D.A., Braund, P.S., Hall, A.S., Olsson, A.G., Doevendans, P.A., Trip, M.D., Tobin, M.D., Hamsten, A., Watkins, H., Koenig, W., Nicolaides, A.N., Teupser, D., Day, I.N., Carlquist, J.F., Gaunt, T.R., Ford, I., Sattar, N., Tsimikas, S., Schwartz, G.G., Lawlor, D.A., Morris, R.W., Sandhu, M.S., Poledne, R., Maitland-van der Zee, A.H., Khaw, K.T., Keating, B.J., Van der Harst, P., Price, J.F., Mehta, S.R., Yusuf, S., Witteman, J.C., Franco, O.H., Jukema, J.W., De Knijff, P., Tybjaerg-Hansen, A., Rader, D.J., Farrall, M., Samani, N.J., Kivimaki, M., Fox, K.A., Humphries, S.E., Anderson, J.L., Boekholdt, S.M., Palmer, T.M., Eriksson, P., Paré, G., Hingorani, A.D., Sabatine, M.S., Mallat, Z., Casas, J.P., Talmud, P.J.
Publikováno v: Journal of the American College of Cardiology
Repositori Institucional de la Universitat Rovira i Virgili
Universitat Rovira i virgili (URV)
Objectives This study sought to investigate the role of secretory phospholipase A2 (sPLA2)-IIA in cardiovascular disease. Background Higher circulating levels of sPLA2-IIA mass or sPLA 2 enzyme activity have been associated with increased risk of car
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::e5575f25f680a9f427470befe62a28f6
https://hdl.handle.net/20.500.14279/3677
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