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Functional studies with IgM and IgA immunoglobulins: binding to pIgR, FcαμR, FcμR, and CDC activities.

Autor: Beyer H; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany.; Institute for Developmental Biology and Neurobiology (IDN), Johannes Gutenberg University, Mainz, Germany., Sommerfeld M; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Grandien K; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Faust C; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Tillmann B; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Leuschner WD; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Régnier-Vigouroux A; Institute for Developmental Biology and Neurobiology (IDN), Johannes Gutenberg University, Mainz, Germany., Weil S; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Rao E; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany., Langer T; Sanofi-Aventis Deutschland GmbH, R&D Large Molecules Research, Frankfurt am Main, Germany.

Publikováno v: APMIS : acta pathologica, microbiologica, et immunologica Scandinavica [APMIS] 2024 Apr; Vol. 132 (4), pp. 277-288. Date of Electronic Publication: 2024 Jan 17.

Pre-clinical development of a novel CD3-CD123 bispecific T-cell engager using cross-over dual-variable domain (CODV) format for acute myeloid leukemia (AML) treatment.

Autor: Bonnevaux H; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Guerif S; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Albrecht J; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Jouannot E; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., De Gallier T; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Beil C; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Lange C; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Leuschner WD; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Schneider M; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Lemoine C; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Caron A; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Amara C; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Barrière C; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Siavellis J; Hopitaux Universitaires Paris Ile De France Ouest, Université Versailles Saint Quentin, Paris, France., Bardet V; Hopitaux Universitaires Paris Ile De France Ouest, Université Versailles Saint Quentin, Paris, France., Luna E; Sanofi Pasteur VaxDesign, Orlando, FL, USA., Agrawal P; Sanofi Pasteur VaxDesign, Orlando, FL, USA., Drake DR; Sanofi Pasteur VaxDesign, Orlando, FL, USA., Rao E; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Wonerow P; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Carrez C; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Blanc V; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Hsu K; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Wiederschain D; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Fraenkel PG; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA., Virone-Oddos A; Sanofi R&D, Vitry-sur-Seine, France; Frankfurt, Germany; and Cambridge, MA, USA.

Publikováno v: Oncoimmunology [Oncoimmunology] 2021 Aug 31; Vol. 10 (1), pp. 1945803. Date of Electronic Publication: 2021 Aug 31 (Print Publication: 2021).

Trispecific broadly neutralizing HIV antibodies mediate potent SHIV protection in macaques.

Autor: Xu L; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Pegu A; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Rao E; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Doria-Rose N; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Beninga J; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., McKee K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Lord DM; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Wei RR; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Deng G; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Louder M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Schmidt SD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Mankoff Z; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Wu L; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Asokan M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Beil C; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Lange C; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Leuschner WD; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Kruip J; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Sendak R; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Kwon YD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Zhou T; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Chen X; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Bailer RT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Wang K; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Choe M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Tartaglia LJ; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA., Barouch DH; Center for Virology and Vaccine Research, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA., O'Dell S; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Todd JP; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Burton DR; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA 02139, USA.; Department of Immunology and Microbiology, International AIDS Vaccine Initiative (IAVI) Neutralizing Antibody Center, Center for HIV/AIDS Vaccine Immunology and Immunogen Discovery, The Scripps Research Institute, La Jolla, CA 92037, USA., Roederer M; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Connors M; National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Koup RA; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Kwong PD; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA., Yang ZY; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA., Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, Bethesda, MD 20892, USA. gary.nabel@sanofi.com jmascola@mail.nih.gov., Nabel GJ; Sanofi, 640 Memorial Drive, Cambridge, MA 02139, USA. gary.nabel@sanofi.com jmascola@mail.nih.gov.

Publikováno v: Science (New York, N.Y.) [Science] 2017 Oct 06; Vol. 358 (6359), pp. 85-90. Date of Electronic Publication: 2017 Sep 20.