Zobrazeno 1 - 10
of 1 185
pro vyhledávání: '"Leurs, P."'
Autor:
Shane Denecke, Madeline F. Malfara, Kelly R. Hodges, Nikki A. Holmes, Andre R. Williams, Julia H. Gallagher-Teske, Julia M. Pascarella, Abigail M. Daniels, Geert Jan Sterk, Rob Leurs, Gordon Ruthel, Rachel Hoang, Megan L. Povelones, Michael Povelones
Publikováno v:
mSphere, Vol 9, Iss 10 (2024)
ABSTRACT Trypanosomatids are single-celled parasites responsible for human and animal disease. Typically, colonization of an insect host is required for transmission. Stable attachment of parasites to insect tissues via their single flagellum coincid
Externí odkaz:
https://doaj.org/article/a6014f6cadd84ebdab05a5e7194aaddd
Publikováno v:
Foundations of Management, Vol 16, Iss 1, Pp 41-58 (2024)
As societal challenges grow, so does the role of universities in finding social and technological solutions. Technical universities are prominent in educating future innovators and developing desired technological and social change. This paper seeks
Externí odkaz:
https://doaj.org/article/0d58864188d545f396d12ce452b41d04
Autor:
Ruixue Xia, Shuang Shi, Zhenmei Xu, Henry F. Vischer, Albert D. Windhorst, Yu Qian, Yaning Duan, Jiale Liang, Kai Chen, Anqi Zhang, Changyou Guo, Rob Leurs, Yuanzheng He
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The histamine H4 receptor (H4R) plays key role in immune cell function and is a highly valued target for treating allergic and inflammatory diseases. However, structural information of H4R remains elusive. Here, we report four cryo-EM struct
Externí odkaz:
https://doaj.org/article/bb329f6ecb7241a28d3a490e5bc87b0e
Autor:
Pierre-André Jarrot, Adrien Mirouse, Sébastien Ottaviani, Simon Cadiou, Jean-Hugues Salmon, Eric Liozon, Simon Parreau, Martin Michaud, Benjamin Terrier, Pierre-Edouard Gavand, Ludovic Trefond, Virginie Lavoiepierre, Jeremy Keraen, Daniel Rekassa, Bastien Bouldoires, Thierry Weitten, Damien Roche, Antoine Poulet, Caroline Charpin, Vincent Grobost, Marion Hermet, Magali Pallure, Chloe Wackenheim, Ludovic Karkowski, Pierre Grumet, Thomas Rogier, Nabil Belkefi, Vincent Pestre, Emilie Broquet, Amélie Leurs, Sophie Gautier, Valérie Gras, Pierre Gilet, Jan Holubar, Nadia Sivova, Nicolas Schleinitz, Jean-Marc Durand, Brice Castel, Alexandre Petrier, Robin Arcani, Baptiste Gramont, Philippe Guilpain, Hubert Lepidi, Pierre-Jean Weiller, Joelle Micallef, David Saadoun, Gilles Kaplanski
Publikováno v:
Human Vaccines & Immunotherapeutics, Vol 20, Iss 1 (2024)
ABSTRACTWe conducted a national in-depth analysis including pharmacovigilance reports and clinical study to assess the reporting rate (RR) and to determine the clinical profile of polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) in COVID-1
Externí odkaz:
https://doaj.org/article/970ddb7d49c04bd4a900d1b8a0d87da2
Autor:
Katrine Bach Habersaat, Anastasia Koylyu, Tiina Likki, Nils Fietje, Martha Scherzer, Vee Snijders, Alona Mazhnaia, Svenja Roy, Merita Berisha, Florie Miftari Basholli, Sabina Catic, Iveta Nagyova, Jonas Sivelä, Francesca Cirulli, Lien Van der Biest, Sladjana Baros, Šeila Cilović Lagarija, Mathilde Schilling, Hannah U. Nohlen, Maria João Forjaz, María Romay-Barja, İlayda Üçüncü, Edith Flaschberger, Tatjana Krajnc Nikolić, Olena Nesterova, Igne Lukmine, Yaiza Rivero-Montesdeoca, Julika Loss, Diana Andreasyan, Milena Carmina Oikonomou, Karina Godoy-Ramirez, Susanne Karregård, Robert Murphy, Jelena Niskanovic, Leen Van Brussel, Miguel Telo de Arriaga, Bogdan Wojtyniak, Cortney Price, Nurila Altymysheva, Karin Stein Jost, Roxane Berjaoui, Panu Saaristo, Joanna Glazewska, Marina Topuridze, Brett Craig, Parvina Mukhtarova, Marina Duishenkulova, Sarah Pace, Mary MacLennan, Marina Bachanovikj, Elke Jakubowski, Halima Zeroug-Vial, Ashley Gould, Adam Cutler, Mariken Leurs, Natalia Silitrari, Eugenia Claudia Bratu, Jenny Young, Viviane Melo Bianco, Robb Butler
Publikováno v:
Public Health in Practice, Vol 7, Iss , Pp 100498- (2024)
Background: Enabling, supporting and promoting positive health-related behaviours is critical in addressing the major public health challenges of our time, and the multifaceted nature of behaviours requires an evidence-based approach. This statement
Externí odkaz:
https://doaj.org/article/47e84caf73724fb8b54c6c2d6d374229
Autor:
Frederik Friis Theisen, Andreas Prestel, Steffie Elkjær, Yannick H. A. Leurs, Nicholas Morffy, Lucia C. Strader, Charlotte O’Shea, Kaare Teilum, Birthe B. Kragelund, Karen Skriver
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract The Arabidopsis thaliana DREB2A transcription factor interacts with the negative regulator RCD1 and the ACID domain of subunit 25 of the transcriptional co-regulator mediator (Med25) to integrate stress signals for gene expression, with elus
Externí odkaz:
https://doaj.org/article/ae9a2b54a3bc4116b99b6733ba0f4295
Autor:
Elleke Leurs, James B. Kirkpatrick
Publikováno v:
Animals, Vol 14, Iss 16, p 2413 (2024)
The surge in wildlife–vehicle collision research has not yet translated into a substantial decrease in animal fatalities. In line with the prevailing view, we suspect that drivers’ behaviour may be the most crucial element. We address a research
Externí odkaz:
https://doaj.org/article/64f1aed56dcf4d7a899698f3d0116705
Publikováno v:
Biomolecules, Vol 14, Iss 7, p 761 (2024)
Alternative splicing significantly enhances the diversity of the G protein-coupled receptor (GPCR) family, including the histamine H3 receptor (H3R). This post-transcriptional modification generates multiple H3R isoforms with potentially distinct pha
Externí odkaz:
https://doaj.org/article/538c618ab9414ac199dcb4a006cfb741
Autor:
Harald Hegen, Klaus Berek, Paola Cavalla, Mikael Christiansen, Andreja Emeršič, Massimiliano Di Filippo, Lorenzo Gaetani, Michaela Hassler, Cyra Leurs, Dejan Milosavljevic, Vincent van Pesch, Thor Petersen, Stefan Presslauer, Igal Rosenstein, Uroš Rot, Christine Schnabl, Charlotte Teunissen, Domizia Vecchio, Marco Vercellino, Florian Deisenhammer
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundKappa free light chains (κ-FLC) in the cerebrospinal fluid (CSF) are an emerging biomarker in multiple sclerosis (MS).ObjectiveTo investigate whether κ-FLC index has similar diagnostic value in patients with primary progressive multiple s
Externí odkaz:
https://doaj.org/article/f2268023c7d1409780b691eaa832cee5
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