A comprehensive AI‐driven analysis of large‐scale omic datasets reveals novel dual‐purpose targets for the treatment of cancer and aging.

Autor: Pun, Frank W.¹ (AUTHOR), Leung, Geoffrey Ho Duen¹ (AUTHOR), Leung, Hoi Wing¹ (AUTHOR), Rice, Jared² (AUTHOR), Schmauck‐Medina, Tomas² (AUTHOR), Lautrup, Sofie² (AUTHOR), Long, Xi¹ (AUTHOR), Liu, Bonnie Hei Man¹ (AUTHOR), Wong, Chun Wai¹ (AUTHOR), Ozerov, Ivan V.¹ (AUTHOR), Aliper, Alex³ (AUTHOR), Ren, Feng⁴ (AUTHOR), Rosenberg, Ari J.⁵ (AUTHOR), Agrawal, Nishant⁶ (AUTHOR), Izumchenko, Evgeny⁵ (AUTHOR) izumchen@bsd.uchicago.edu, Fang, Evandro F.^2,7 (AUTHOR) e.f.fang@medisin.uio.no, Zhavoronkov, Alex^1,3,8 (AUTHOR) alex@insilico.com

Publikováno v: Aging Cell. Dec2023, Vol. 22 Issue 12, p1-19. 19p.

Precious2GPT: the combination of multiomics pretrained transformer and conditional diffusion for artificial multi-omics multi-species multi-tissue sample generation.

Autor: Sidorenko, Denis, Pushkov, Stefan, Sakip, Akhmed, Leung, Geoffrey Ho Duen, Lok, Sarah Wing Yan, Urban, Anatoly, Zagirova, Diana, Veviorskiy, Alexander, Tihonova, Nina, Kalashnikov, Aleksandr, Kozlova, Ekaterina, Naumov, Vladimir, Pun, Frank W., Aliper, Alex, Ren, Feng, Zhavoronkov, Alex

Publikováno v: NPJ Aging; 8/8/2024, Vol. 10 Issue 1, p1-14, 14p

Leveraging AI to identify dual-purpose aging and disease targets

Autor: Leung, Geoffrey Ho Duen, Wong, Chun Wai, Pun, Frank W., Aliper, Alex, Ren, Feng, Zhavoronkov, Alex

Publikováno v: Expert Opinion on Therapeutic Targets; June 2024, Vol. 28 Issue: 6 p473-476, 4p

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