Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Leukocyte degranulation"'
Autor:
Ting Wang, Guangrui Huang, Wei Wang, Shen Zhang, Jiarui Wu, Ting’an Li, Xinhui Gao, Kunyu Li, Xiaopu Sang, Anlong Xu, Leiming You
Publikováno v:
Chinese Medicine, Vol 16, Iss 1, Pp 1-15 (2021)
Chinese Medicine
Chinese Medicine
Background: To investigate the microRNA (miRNA)-gene interactions underlying leukocyte functions and characteristics, especially the potential serum biomarkers, implicated in the traditional Chinese medicine (TCM)-defined Pi-qi-deficiency syndrome (P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::941450027dcada6df1ca44cc9bc89557
https://doaj.org/article/8bf84fd7e3d74a3d8be30cdfa310e3b2
https://doaj.org/article/8bf84fd7e3d74a3d8be30cdfa310e3b2
Publikováno v:
Vestnik Urologii, Vol 7, Iss 2, Pp 66-73 (2019)
Background . Benign prostatic hyperplasia (BPH) is the most common disease in older men. BPH pathophysiology is poorly understood. Although, it is known that the transmission of androgenergic signals and the reactivity of prostate's stroma as well as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b33000fa112068658c9e3e85e47f3565
https://doi.org/10.21886/2308-6424-2019-7-2-66-73
https://doi.org/10.21886/2308-6424-2019-7-2-66-73
Autor:
Qiuqiu Lin, Wenzhi Zhou, Zhongyuan Xiang, Tian Li, Gan Huang, Zhiguang Zhou, Juan Huang, Yue Tong, Yanfei Wang, Yixuan Xing, Yang Xiao, Yanhua Li
Publikováno v:
Frontiers in Endocrinology
Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology, Vol 11 (2020)
ObjectiveLatent autoimmune diabetes in adults (LADA) is an autoimmune diabetes characterized by slowly progressive of β-cell function deterioration. Our previous finding demonstrated that neutrophil numbers and migration abilities display distinct l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d4bf93300ab47e7bfa7577b381fff44
http://europepmc.org/articles/PMC7775642
http://europepmc.org/articles/PMC7775642
Autor:
Rhoneil Pena, Phi Quach, Andrew Moffett, Jicai Huang, Marlene Hennessy, Dawei Sheng, Jonathan Zalevsky, Takahiro Miyazaki, Janet Cetz, Ping Zhang, Peiwen Kuo, Loui Madakamutil, Sara Sheibani, Saul Kivimae, Mekhala Maiti, Joanna Wilczek, Thomas Chang, Yinyan Tang, Kirk Peter Benedict, Murali Addepalli, Palakshi Obalapur, Werner Rubas
Publikováno v:
Journal for Immunotherapy of Cancer
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 5 (2021)
BackgroundNKTR-255 is a novel polyethylene glycol-conjugate of recombinant human interleukin-15 (rhIL-15), which was designed to retain all known receptor binding interactions of the IL-15 molecule. We explored the biologic and pharmacologic differen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c255306cc60e8024b14e49aca77699a1
https://doi.org/10.1136/jitc-2020-002024
https://doi.org/10.1136/jitc-2020-002024
Autor:
Amanda Caroline Camillo-Andrade, Saloe Bispo, Marlon D.M. Santos, Juliana de Saldanha da Gama Fischer, Fábio C. S. Nogueira, Bernardo Bonilauri, Nilson Ivo Tonin Zanchin, Paulo C. Carvalho
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics. 1869:140581
Human peripheral blood mononuclear cells (PBMC) are key to several diagnostics assays and basic science research. Blood pre-analytical variations that occur before obtaining the PBMC fraction can significantly impact the assays results, including via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d5addefba6f0a9600dcfe47d8ad7b14
https://doi.org/10.1016/j.bbapap.2020.140581
https://doi.org/10.1016/j.bbapap.2020.140581
Autor:
Tomoki Maekawa, Xiaofei Li, Kai Bao, Ruel A. Briones, Cristina A.G. Garcia, Edimara S. Reis, Ranillo R.G. Resuello, Nagihan Bostanci, Joel V. Tuplano, John D. Lambris, Christian Panse, Jonas Grossmann, George Hajishengallis
BACKGROUND AND AIM: Periodontitis is a prevalent chronic inflammatory disease associated with dysbiosis. Although complement inhibition has been successfully used to treat periodontitis in animal models, studies globally analysing inflamed tissue pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::597cf93aaf4c1a95fe7cf461696f5635
https://www.zora.uzh.ch/id/eprint/162412/
https://www.zora.uzh.ch/id/eprint/162412/
Autor:
S Alberto Manchego, S Gina Castro, C Nieves Sandoval, María del Carmen Inga, G Hermelinda Rivera, C Cesar Burga
Publikováno v:
Revista de Investigaciones Veterinarias del Perú, Volume: 27, Issue: 2, Pages: 333-343, Published: APR 2016
Revista de Investigaciones Veterinarias del Perú; Vol 27 No 2 (2016); 333-343
Revista de Investigaciones Veterinarias del Perú; Vol. 27 Núm. 2 (2016); 333-343
Revista de Investigaciones Veterinarias del Perú; Vol 27 No 2 (2016); 333-343
Revista de Investigaciones Veterinarias del Perú; Vol. 27 Núm. 2 (2016); 333-343
En el presente trabajo se buscó determinar el efecto tóxico in vitro del extracto proteico de macroquistes de Sarcocystis aucheniae sobre leucocitos circulantes de conejo (citotoxicidad). Se trabajó con cinco concentraciones de extracto proteico (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34c4278dbb4cb2250b77c391f9b9d48c
http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1609-91172016000200016&lng=en&tlng=en
http://www.scielo.org.pe/scielo.php?script=sci_arttext&pid=S1609-91172016000200016&lng=en&tlng=en
Publikováno v:
The Journal of Immunology. 178:416-427
We examined the roles of cGMP-dependent protein kinase (PKG) and PI3K in degranulation induced by fMLF and by FcεRI cross-linking. In rat basophilic leukemia-2H3 cells expressing formyl peptide receptor, the PKG inhibitors KT5823 and Rp-8-Br-PET-cGM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7ea24e2517940352d4649d9e67115ad
https://doi.org/10.4049/jimmunol.178.1.416
https://doi.org/10.4049/jimmunol.178.1.416
Autor:
Jan G. J. van de Winkel, Marc D. Jansen, Cees van Kooten, Michiaki Koga, Nobuhiro Yuki, Leonard H. van den Berg, Keiichiro Susuki, W-Ludo van der Pol, John H. J. Wokke, Nina M. van Sorge
Publikováno v:
Journal of Neuroimmunology. 182:177-184
The capacity of ganglioside-specific autoantibodies to recruit leukocyte effector functions was studied. Serum samples from 87 patients with Guillain-Barré (GBS) or Miller Fisher syndrome (MFS), containing GM1-, GQ1b-, or GD1b-specific IgG or IgA, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f6e843fe9f0a08bf95e0149697c9c92
https://doi.org/10.1016/j.jneuroim.2006.10.015
https://doi.org/10.1016/j.jneuroim.2006.10.015
Autor:
Dennis E. Chenoweth
Human C5a anaphylatoxin is a potent bioactive molecule that possesses both spasmogenic and leukocyte-related properties. As such, it normally serves as a local mediator of the acute inflammatory response. Additionally, C5a, through its actions of mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::23a40712e8acbc95bbeb630c82ec1b9d
https://doi.org/10.1159/000414615
https://doi.org/10.1159/000414615