Zobrazeno 1 - 10
of 1 200
pro vyhledávání: '"Leufkens P"'
Autor:
Jacob M van Laar, Anna de Goede, Gerty Schreibelt, Arie Jan Stoppelenburg, I Jolanda M de Vries, Paco Welsing, Bouke Koeneman, Evert-Jan Breman, Laureen Lammers, Tjitske Duiveman-de Boer, Willem van Eden, Paul Leufkens, Femke Broere
Publikováno v:
BMJ Open, Vol 14, Iss 9 (2024)
Introduction In rheumatoid arthritis (RA), immunosuppressive therapies may achieve symptomatic relief, but do not induce long-term, drug-free remission. Meanwhile, the lifelong use of immunosuppressive drugs confers increased risk for malignancy and
Externí odkaz:
https://doaj.org/article/048d163ecbc2444592ca57a8e33b4efc
Autor:
Doerine J Postma, Magali L A Heijkoop, Peter A G M De Smet, Kim Notenboom, Hubert G M Leufkens, Aukje K Mantel-Teeuwisse
Publikováno v:
Journal of Medical Internet Research, Vol 26, p e51317 (2024)
BackgroundEarly identification is critical for mitigating the impact of medicine shortages on patients. The internet, specifically social media, is an emerging source of health data. ObjectiveThis study aimed to explore whether a routine analysis of
Externí odkaz:
https://doaj.org/article/9741756b0d9449a0bdfdf41dc735f145
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 19, Iss 1, Pp 1-16 (2024)
Abstract Background Over the last twenty years of orphan drug regulation in Europe, the regulatory framework has increased its complexity, with different regulatory paths and tools engineered to facilitate the innovation and accelerate approvals. Rec
Externí odkaz:
https://doaj.org/article/a4c1b64ebacc4016a3d998cbe0c3682e
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-7 (2024)
Abstract Introduction The COVID-19 pandemic highlighted an urgent need for harmonised requirements for the regulation of medicines. To fully implement harmonised medicines regulations across Africa, common technical standards of medicine regulations
Externí odkaz:
https://doaj.org/article/35574983a7684074aa0f4468670a0e65
Autor:
Heike Müller, Jan K. Straßmann, Anne S. Baier, Verena von Bülow, Frederik Stettler, Maximilian J. Hagen, Fabian P. Schmidt, Annette Tschuschner, Andreas R. Schmid, Daniel Zahner, Kernt Köhler, Jörn Pons-Kühnemann, Daniel Leufkens, Dieter Glebe, Surmeet Kaur, Max F. Möscheid, Simone Haeberlein, Christoph G. Grevelding, Ralf Weiskirchen, Mohamed El-Kassas, Khaled Zalata, Elke Roeb, Martin Roderfeld
Publikováno v:
Cells, Vol 13, Iss 19, p 1643 (2024)
Schistosomiasis affects over 250 million people worldwide, with the highest prevalence at the age of 10–14 years. The influence of the host’s age on the severity of liver damage is unclear. We infected male 8, 14, and 20-week-old mice with S. man
Externí odkaz:
https://doaj.org/article/7fb650e6fac343df8883926123b51846
Publikováno v:
PLoS ONE, Vol 19, Iss 7, p e0306302 (2024)
BackgroundThe meaning of the toothbrushing technique for the effectivity of toothbrushing in terms of plaque removal and parameters of gingivitis is unknown. This systematic review and network meta-analysis (NMA) aimed to synthesize evidence from ran
Externí odkaz:
https://doaj.org/article/be729e1f2e264e6f873dae7c2deccfb3
Akademický článek
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Akademický článek
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Autor:
Doerine J. Postma, Kim Notenboom, Peter A. G. M. De Smet, Hubert G. M. Leufkens, Aukje K. Mantel-Teeuwisse
Publikováno v:
Journal of Pharmaceutical Policy and Practice, Vol 16, Iss 1, Pp 1-12 (2023)
Abstract Introduction Current research to assess the impact that medicine shortages have on patients is limited to general aspects, such as the prevalence of shortages and product characteristics. The aim of this study is to assess the overall impact
Externí odkaz:
https://doaj.org/article/3d289edd958c4e21a58cb57adbccd478
Autor:
Doerine J. Postma, Peter A. G. M. De Smet, Kim Notenboom, Hubert G. M. Leufkens, Aukje K. Mantel-Teeuwisse
Publikováno v:
BMC Health Services Research, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Medicine shortages are often described in plain numbers, suggesting all shortages have a uniform impact. However, some shortages have a direct and serious effect on patients and need a prompt reaction from stakeholders. This study
Externí odkaz:
https://doaj.org/article/9ff565350f0f4e92a9db092adaeacfd3