Transgenic Kallikrein 14 Mice Display Major Hair Shaft Defects Associated with Desmoglein 3 and 4 Degradation, Abnormal Epidermal Differentiation, and IL-36 Signature

Autor: Gouin, Olivier, Barbieux, Claire, Leturcq, Florent, Bonnet des Claustres, Mathilde, Petrova, Evgeniya, Hovnanian, Alain

Publikováno v: In Journal of Investigative Dermatology June 2020 140(6):1184-1194

Netherton syndrome subtypes share IL-17/IL-36 signature with distinct IFN-α and allergic responses

Autor: Barbieux, Claire, Bonnet Des Claustres, Mathilde, Fahrner, Matthias, Petrova, Evgeniya, Tsoi, Lam, Gouin, Olivier, Leturcq, Florent, Nicaise-Roland, Pascale, Bole, Christine, Béziat, Vivien, Bourrat, Emmanuelle, Schilling, Oliver, Gudjonsson, Johann, Hovnanian, Alain

Publikováno v: Journal of Allergy and Clinical Immunology
Journal of Allergy and Clinical Immunology, 2021, ⟨10.1016/j.jaci.2021.08.024⟩
Journal of Allergy and Clinical Immunology, Elsevier, 2021, ⟨10.1016/j.jaci.2021.08.024⟩

International audience; Background: Netherton syndrome (NS) is a rare recessive skin disorder caused by loss-of-function mutations in SPINK5 encoding the protease inhibitor LEKTI (lymphoepithelial Kazal-type–related inhibitor). NS patients experien

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::45a772f891d8b291c5ed4aaba2c5a0e7
https://hal.science/hal-03559943/file/06-netherton-syndrome-subtypes-share-IL.pdf