Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Letizia Lanzetti"'
Autor:
Deborah Mesa, Elisa Barbieri, Andrea Raimondi, Stefano Freddi, Giorgia Miloro, Gorana Jendrisek, Giusi Caldieri, Micaela Quarto, Irene Schiano Lomoriello, Maria Grazia Malabarba, Arianna Bresci, Francesco Manetti, Federico Vernuccio, Hind Abdo, Giorgio Scita, Letizia Lanzetti, Dario Polli, Carlo Tacchetti, Paolo Pinton, Massimo Bonora, Pier Paolo Di Fiore, Sara Sigismund
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract One open question in the biology of growth factor receptors is how a quantitative input (i.e., ligand concentration) is decoded by the cell to produce specific response(s). Here, we show that an EGFR endocytic mechanism, non-clathrin endocyt
Externí odkaz:
https://doaj.org/article/1aea93372b324f868e8be4a452c68516
Autor:
Stefano Confalonieri, Bronislava Matoskova, Rosa Pennisi, Flavia Martino, Agnese De Mario, Giorgia Miloro, Francesca Montani, Luca Rotta, Mahila Esmeralda Ferrari, Laura Gilardi, Francesco Ceci, Chiara Maria Grana, Rosario Rizzuto, Cristina Mammucari, Pier Paolo Di Fiore, Letizia Lanzetti
Publikováno v:
Advanced Science, Vol 11, Iss 28, Pp n/a-n/a (2024)
Abstract Metabolic alterations in cancers can be exploited for diagnostic, prognostic, and therapeutic purposes. This is exemplified by 18F‐fluorodeoxyglucose (FDG)‐positron emission tomography (FDG‐PET), an imaging tool that relies on enhanced
Externí odkaz:
https://doaj.org/article/78823203ee814083a81792ce84af785c
Autor:
Søs Grønbæk Holdgaard, Valentina Cianfanelli, Emanuela Pupo, Matteo Lambrughi, Michal Lubas, Julie C. Nielsen, Susana Eibes, Emiliano Maiani, Lea M. Harder, Nicole Wesch, Mads Møller Foged, Kenji Maeda, Francesca Nazio, Laura R. de la Ballina, Volker Dötsch, Andreas Brech, Lisa B. Frankel, Marja Jäättelä, Franco Locatelli, Marin Barisic, Jens S. Andersen, Simon Bekker-Jensen, Anders H. Lund, Vladimir V. Rogov, Elena Papaleo, Letizia Lanzetti, Daniela De Zio, Francesco Cecconi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-19 (2019)
Centrosomes drive mitotic spindle formation and chromosome segregation. Here, the authors show that centrosome stability is regulated by selective autophagic degradation of centriolar satellite components in a process they term doryphagy, connecting
Externí odkaz:
https://doaj.org/article/332640b7f2f048bebeba04c9ee651443
Publikováno v:
Molecular Oncology, Vol 12, Iss 1, Pp 3-20 (2018)
The physiological function of the epidermal growth factor receptor (EGFR) is to regulate epithelial tissue development and homeostasis. In pathological settings, mostly in lung and breast cancer and in glioblastoma, the EGFR is a driver of tumorigene
Externí odkaz:
https://doaj.org/article/e5bc06a6ca424042abe909cf1e19bb8b
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Tumors driven by mutant KRAS are among the most aggressive and refractory to treatment. Unfortunately, despite the efforts, targeting alterations of this GTPase, either directly or by acting on the downstream signaling cascades, has been, so far, lar
Externí odkaz:
https://doaj.org/article/2e93e2bf1ea4426ab4748661dc8fde8d
Autor:
Emanuela Pupo, Daniele Avanzato, Marco Scianna, Amanda Oldani, Guido Serini, Letizia Lanzetti
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 9, p 2575 (2018)
RAB5 is a small GTPase that belongs to the wide family of Rab proteins and localizes on early endosomes. In its active GTP-bound form, RAB5 recruits downstream effectors that, in turn, are responsible for distinct aspects of early endosome function,
Externí odkaz:
https://doaj.org/article/bafe34d75d764faba12420faad91c299
Autor:
Letizia Lanzetti, Anna Sapino, Pier Paolo Di Fiore, Carlos Caldas, Oscar M. Rueda, Alejandra Bruna, Salvatore Pece, Chiara Luise, Giovanni Bertalot, Claudio Isella, Nadia Ducano, Emanuela Pupo, Daniele Avanzato
S1-Prognostic value of USP6NL gain in the METABRIC dataset S2-Correleation of USP6NL protein expression with clinical-pathological parameters in the TMA cohort
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ee3cb1864abc116e07e451c6ceaceaa
https://doi.org/10.1158/0008-5472.22420413
https://doi.org/10.1158/0008-5472.22420413
Autor:
Paolo M. Comoglio, Letizia Lanzetti, Livio Trusolino, Timothy Perera, Daniele Avanzato, Elisa Vigna, Barbara Lupo, Nadia Ducano, Emanuela Pupo
In vivo rebound MET activation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48ed0a6ab0c3b30bbde9179e8621719c
https://doi.org/10.1158/0008-5472.22411443.v1
https://doi.org/10.1158/0008-5472.22411443.v1
Autor:
Letizia Lanzetti, Anna Sapino, Pier Paolo Di Fiore, Carlos Caldas, Oscar M. Rueda, Alejandra Bruna, Salvatore Pece, Chiara Luise, Giovanni Bertalot, Claudio Isella, Nadia Ducano, Emanuela Pupo, Daniele Avanzato
USP6NL overexpression inhibits GLUT1 endocytosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cfe892d4b89aa725bc343c81ea45a47
https://doi.org/10.1158/0008-5472.22420422
https://doi.org/10.1158/0008-5472.22420422
Autor:
Riccardo Taulli, Carola Ponzetto, Thomas Tuschl, Marc Ladanyi, Samuel Singer, Roberto Chiarle, Paolo Provero, Ugo Ala, Alessandro Morotti, Giovanna Carrà, Letizia Lanzetti, Silvia Miretti, Valentina Foglizzo, Deborah Morena, Marcello Francesco Lingua, Francesca Bersani
Detailed version of the Materials and Methods and list of oligonucleotides and antibodies used.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1992374bf7116dced84b95a4a7d23af8
https://doi.org/10.1158/0008-5472.22412544.v1
https://doi.org/10.1158/0008-5472.22412544.v1