Hmgb3 is regulated by microRNA-206 during muscle regeneration.

Autor: Simona Maciotta, Mirella Meregalli, Letizia Cassinelli, Daniele Parolini, Andrea Farini, Giulia Del Fraro, Francesco Gandolfi, Mattia Forcato, Sergio Ferrari, Davide Gabellini, Silvio Bicciato, Giulio Cossu, Yvan Torrente

Publikováno v: PLoS ONE, Vol 7, Iss 8, p e43464 (2012)

MicroRNAs (miRNAs) have been recently involved in most of human diseases as targets for potential strategies to rescue the pathological phenotype. Since the skeletal muscle is a spread-wide highly differentiated and organized tissue, rescue of severe

Externí odkaz: https://doaj.org/article/5f9c729a42434d498f389cd5d3c066f1

25(OH)D Levels in Relation to Gender, Overweight, Insulin Resistance, and Inflammation in a Cross-Sectional Cohort of Northern Italian Workers: Evidence in Support of Preventive Health Care Programs

Autor: Claudia Eleonora Barberi, Amedea Silvia Tirelli, Letizia Cassinelli, Filomena Napolitano, Michela Mutti, Irene Felicetta, Luciano Riboldi, Luisella Vigna, Laura Tomaino

Publikováno v: Journal of the American College of Nutrition. 36:253-260

In recent years, the welfare of workers and the prevention of chronic disabling diseases has become a topic of great interest. This study investigates serum levels of total 25-hydroxyvitamin D (25(OH)D) in a cohort of overweight-obese and insulin-res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27b601c539d72cb80ef76483419f7b6f
https://doi.org/10.1080/07315724.2016.1264280

Therapeutic Potential of Immunoproteasome Inhibition in Duchenne Muscular Dystrophy

Autor: Pamela Bella, Nicola Fusco, Filomena Napolitano, Silvano Bosari, Clementina Sitzia, Stefano Gatti, Rosita Rigoni, Barbara Cassani, Anna Villa, Rita Maiavacca, F. Colleoni, Letizia Cassinelli, Yvan Torrente, Chiara Villa, Andrea Farini

Publikováno v: Molecular Therapy. 24:1898-1912

Duchenne muscular dystrophy is an inherited fatal genetic disease characterized by mutations in dystrophin gene, causing membrane fragility leading to myofiber necrosis and inflammatory cell recruitment in dystrophic muscles. The resulting environmen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82d6003efeba0fb321ab5b0d9e854d00
https://doi.org/10.1038/mt.2016.162

Perspectives of stem cell therapy in Duchenne muscular dystrophy

Autor: Marzia Belicchi, P. Razini, Yvan Torrente, Mirella Meregalli, Clementina Sitzia, Andrea Farini, Daniele Parolini, Letizia Cassinelli

Publikováno v: FEBS Journal; Vol 280
FEBS Journal

Muscular dystrophies are heritable and heterogeneous neuromuscular disorders characterized by the primary wasting of skeletal muscle, usually caused by mutations in the proteins forming the link between the cytoskeleton and the basal lamina. As a res

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a651c9d6318e4f7b9e49ca87eca8c402
https://doi.org/10.1111/febs.12083

Inositol 1,4,5-trisphosphate (IP3)-dependent Ca2+ signaling mediates delayed myogenesis in Duchenne muscular dystrophy fetal muscle

Autor: Augusto Colombo, Mirella Meregalli, D. Parolini, Federica Colleoni, Umberto Giovanella, Letizia Cassinelli, Simona Maciotta, Clementina Sitzia, Yvan Torrente, A. Farini

Publikováno v: Development (Camb.) 143 (2016): 658–669. doi:10.1242/dev.126193
info:cnr-pdr/source/autori:Farini A.; Sitzia C.; Cassinelli L.; Colleoni F.; Parolini D.; Giovanella U.; Maciotta S.; Colombo A.; Meregalli M.; Torrente Y./titolo:Inositol 1,4,5-trisphosphate (IP3)-dependent Ca2+ signaling mediates delayed myogenesis in Duchenne muscular dystrophy fetal muscle/doi:10.1242%2Fdev.126193/rivista:Development (Camb.)/anno:2016/pagina_da:658/pagina_a:669/intervallo_pagine:658–669/volume:143

Duchenne muscular dystrophy (DMD) is a progressive neuromuscular disorder characterized by muscle wasting and premature death. The defective gene is dystrophin, a structural protein, absence of which causes membrane fragility and myofiber necrosis. S

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8edb31e84321586c491296e79eeda945
https://pubmed.ncbi.nlm.nih.gov/26884398