Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Letizia Antonilli"'
Autor:
Letizia Antonilli, Lorenza De Carolis, Giuseppina I. Togna, Melania Dovizio, Adele Salemme, Paolo Nencini, Anna Rita Togna, Paola Patrignani
Publikováno v:
Neuropharmacology. 75:391-398
Morphine is mainly transformed to morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G) in the liver. Glucuronidation is also performed by rat brain homogenates and UDP-glucuronosyltransferases (UGTs) are present in the brain. Here we investi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc1d26738fbab1a12b808d01342ed77d
https://doi.org/10.1016/j.neuropharm.2013.08.019
https://doi.org/10.1016/j.neuropharm.2013.08.019
Autor:
Laura Guarcini, Rosario Nicoletti, Paolo Nencini, Letizia Antonilli, Giuseppina I. Togna, Filomena Sanasi, Armandodoriano Bianco, Giovanna Sabatini, Anna Rita Togna, Alessandro Venditti
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:7955-7963
We have previously found that phenanthrenic opioids, including codeine, modulate morphine glucuronidation in the rat. Here codeine and five of its derivatives were compared in their effects on the synthesis of morphine-3-glucuronide (M3G) and morphin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5572418825dbe707756959371034a3b1
https://doi.org/10.1016/j.bmc.2013.09.062
https://doi.org/10.1016/j.bmc.2013.09.062
Autor:
Paolo Nencini, Maria Caterina Grassi, Letizia Antonilli, Anna Maria Cioce, Franco Dei Giudici
Publikováno v:
Pharmacological Research. 55:117-121
Cocaine abusers frequently report taking the drug in association with alcohol. This combined intake leads to the synthesis of cocaethylene, an active metabolite with effects similar to those of cocaine, but more prolonged. Since pharmacological effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e4f58ce64052d3c212c7710ba17a73a
https://doi.org/10.1016/j.phrs.2006.11.005
https://doi.org/10.1016/j.phrs.2006.11.005
Publikováno v:
Pharmacological Research. 44:41-45
Concurrent ingestion of alcohol and cocaine is a common occurrence in cocaine-dependent individuals. Cocaethylene is a pharmacologically active metabolite of cocaine that is formed in the liver in the presence of ethanol. The effects of ethanol combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43886360443f8d6513724e0699aa7c5b
https://doi.org/10.1006/phrs.2001.0834
https://doi.org/10.1006/phrs.2001.0834
Publikováno v:
Pharmacology Biochemistry and Behavior. 66:199-204
The morphine-like properties of a series of aminoalkyl- and cycloalkylamino-naphtalenic derivatives of 17-methyl-17-azaequilenine were studied in rats trained to discriminate morphine (5.6 mg/kg IP) from vehicle in a two-lever operant behavioral proc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::806956ef90e43593ea1ef18f39f343c1
https://doi.org/10.1016/s0091-3057(00)00202-1
https://doi.org/10.1016/s0091-3057(00)00202-1
Autor:
Laura Maggi, Maria Scianni, Maria Amalia Di Castro, Giuseppina Chece, Gloria Cristalli, Letizia Antonilli, Cristina Limatola
Publikováno v:
Journal of Neuroinflammation
Journal of Neuroinflammation, BioMed Central, 2013, 10, pp.108. ⟨10.1186/1742-2094-10-108⟩
Journal of Neuroinflammation, BioMed Central, 2013, 10, pp.108. ⟨10.1186/1742-2094-10-108⟩
Background N-Methyl-d-aspartate receptors (NMDARs) play fundamental roles in basic brain functions such as excitatory neurotransmission and learning and memory processes. Their function is largely regulated by factors released by glial cells, includi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a90f80ba9560e3262ee85a56eab031e
https://doi.org/10.1186/1742-2094-10-108
https://doi.org/10.1186/1742-2094-10-108
Autor:
Letizia Antonilli, Valentina Brusadin, Paola Patrignani, Melania Dovizio, Paolo Nencini, Lorenza De Carolis, Giuseppina I. Togna, Anna Rita Togna
Publikováno v:
European journal of pharmacology. 693(1-3)
We have previously found that phenantrenic opioids, such as heroin or naltrexone, modulate morphine glucuronidation in the rat. Here we further investigated the effects of phenantrenic opioids on morphine glucuronidation comparing the effects of code
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::946be45d144940682a952b9f358308af
https://pubmed.ncbi.nlm.nih.gov/23010468
https://pubmed.ncbi.nlm.nih.gov/23010468
Autor:
Flavia Trettel, Bertil B. Fredholm, Nico van Rooijen, Letizia Antonilli, Valentina Brusadin, Clotilde Lauro, Raffaela Cipriani, Fabrizio Eusebi, Giuseppina Chece, Cristina Limatola, Myriam Catalano
Publikováno v:
Lauro, C, Cipriani, R, Catalano, M, Trettel, F, Chece, G, Brusadin, V, Antonilli, L, van Rooijen, N, Eusebi, F, Fredholm, B B & Limatola, C 2010, ' Adenosine A(1) Receptors and Microglial Cells Mediate CX3CL1-Induced Protection of Hippocampal Neurons Against Glu-Induced Death ', Neuropsychopharmacology, vol. 35, no. 7, pp. 1550-1559 . https://doi.org/10.1038/npp.2010.26
Neuropsychopharmacology, 35(7), 1550-1559. Nature Publishing Group
Neuropsychopharmacology, 35(7), 1550-1559. Nature Publishing Group
Fractalkine/CX3CL1 is a neuron-associated chemokine, which modulates microglia-induced neurotoxicity activating the specific and unique receptor CX3CR1. CX3CL1/CX3CR1 interaction modulates the release of cytokines from microglia, reducing the level o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2c2e1b7a4b9cb2bd5076b859fc844e7
https://research.vumc.nl/en/publications/de25a0e8-9b82-4edb-afc0-45f5a77d9c29
https://research.vumc.nl/en/publications/de25a0e8-9b82-4edb-afc0-45f5a77d9c29
Autor:
Paolo Nencini, Letizia Antonilli, Aldo Badiani, Michele Milella, Valentina Brusadin, Fabrizia Sobrero
We have previously found that repeated exposure to heroin reduces liver synthesis of morphine-3-glucuronide (M3G) and increases the production of morphine-6-glucuronide (M6G), which normally is not formed in the rat. By contrast repeated exposure to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9acdb8a4b7a472918c60b7ce943441bd
http://hdl.handle.net/11573/364490
http://hdl.handle.net/11573/364490
Autor:
Letizia Antonilli, Raffaela Cipriani, Davide Ragozzino, Valentina Brusadin, Clotilde Lauro, Silvia Di Angelantonio, Cristina Limatola, Fabrizia Sobrero
The chemokine fractalkine (CX3CL1) is constitutively expressed by central neurons, regulating microglial responses including chemotaxis, activation, and toxicity. Through the activation of its own specific receptor, CX3CR1, CX3CL1 exerts both neuropr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bc2433df00fa1f2ac01ad632702350f3
http://hdl.handle.net/11573/358622
http://hdl.handle.net/11573/358622