Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Letitia Ciortan"'
Autor:
Loredana Iacobescu, Andrea Olivia Ciobanu, Razvan Macarie, Mihaela Vadana, Letitia Ciortan, Monica Madalina Tucureanu, Elena Butoi, Maya Simionescu, Dragos Vinereanu
Publikováno v:
Current Issues in Molecular Biology, Vol 46, Iss 8, Pp 8499-8511 (2024)
Recent studies reported that circulating microRNAs (miRNAs) can target different metalloproteases (MMPs) involved in matrix remodeling and plaque vulnerability. Consequently, they might have a role in the diagnosis and prognosis of coronary artery di
Externí odkaz:
https://doaj.org/article/603256f361ea443085e231b4c09a986a
Autor:
Elena Barbu, Andreea Cristina Mihaila, Ana-Maria Gan, Letitia Ciortan, Razvan Daniel Macarie, Monica Madalina Tucureanu, Alexandru Filippi, Andra Ioana Stoenescu, Stefanita Victoria Petrea, Maya Simionescu, Serban Mihai Balanescu, Elena Butoi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 10, p 5107 (2024)
Despite neutrophil involvement in inflammation and tissue repair, little is understood about their inflammatory status in acute coronary syndrome (ACS) patients with poor outcomes. Hence, we investigated the potential correlation between neutrophil i
Externí odkaz:
https://doaj.org/article/5105d07b01014313ac446dd0a15df92c
Autor:
Monica Madalina Tucureanu, Letitia Ciortan, Razvan Daniel Macarie, Andreea Cristina Mihaila, Ionel Droc, Elena Butoi, Ileana Manduteanu
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 5, p 3048 (2024)
Aortic valve disease (AVD) represents a global public health challenge. Research indicates a higher prevalence of diabetes in AVD patients, accelerating disease advancement. Although the specific mechanisms linking diabetes to valve dysfunction remai
Externí odkaz:
https://doaj.org/article/898d0d2a803b457494cd306f11ae1c5c
Autor:
Andreea Cristina Mihaila, Letitia Ciortan, Monica Madalina Tucureanu, Maya Simionescu, Elena Butoi
Publikováno v:
Cells, Vol 13, Iss 3, p 208 (2024)
Following myocardial infarction (MI), blood neutrophils quickly and extensively infiltrate the heart, where they are temporally polarized into pro-inflammatory (N1) and anti-inflammatory (N2) subpopulations. Neutrophil transmigration is rapidly follo
Externí odkaz:
https://doaj.org/article/6add2033f83a4107922db45fa95d30eb
Autor:
Andreea C. Mihaila, Letitia Ciortan, Razvan D. Macarie, Mihaela Vadana, Sergiu Cecoltan, Mihai Bogdan Preda, Ariana Hudita, Ana-Maria Gan, Gabriel Jakobsson, Monica M. Tucureanu, Elena Barbu, Serban Balanescu, Maya Simionescu, Alexandru Schiopu, Elena Butoi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Neutrophils have been classically viewed as a homogenous population. Recently, neutrophils were phenotypically classified into pro-inflammatory N1 and anti-inflammatory N2 sub-populations, but the functional differences between the two subtypes are n
Externí odkaz:
https://doaj.org/article/c7e22488342b47439dfb2d1d1d46675e
Autor:
Sergiu Cecoltan, Letitia Ciortan, Razvan D. Macarie, Mihaela Vadana, Andreea C. Mihaila, Monica Tucureanu, Mihaela-Loredana Vlad, Ionel Droc, Mihaela Gherghiceanu, Agneta Simionescu, Dan Teodor Simionescu, Elena Butoi, Ileana Manduteanu
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Background: Valvular endothelial cells (VEC) have key roles in maintaining valvular integrity and homeostasis, and dysfunctional VEC are the initiators and major contributors to aortic valve disease in diabetes. Previous studies have shown that HG st
Externí odkaz:
https://doaj.org/article/3e40bb1634e842aab75c613b393ecb72
Autor:
Mihaela Vadana, Sergiu Cecoltan, Letitia Ciortan, Razvan D. Macarie, Andreea C. Mihaila, Monica M. Tucureanu, Ana-Maria Gan, Maya Simionescu, Ileana Manduteanu, Ionel Droc, Elena Butoi
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 7, p 3776 (2022)
Parathyroid hormone (PTH) is a key regulator of calcium, phosphate and vitamin D metabolism. Although it has been reported that aortic valve calcification was positively associated with PTH, the pathophysiological mechanisms and the direct effects of
Externí odkaz:
https://doaj.org/article/fb26b1e74edb4f5898ff2f7bcf746743
Autor:
Letitia Ciortan, Razvan Daniel Macarie, Sergiu Cecoltan, Mihaela Vadana, Monica Madalina Tucureanu, Andreea Cristina Mihaila, Ionel Droc, Elena Butoi, Ileana Manduteanu
Publikováno v:
Polymers, Vol 12, Iss 12, p 2786 (2020)
Calcific aortic valve disease (CAVD), a degenerative disease characterized by inflammation, fibrosis and calcification, is accelerated in diabetes. Hyperglycemia contributes to this process by mechanisms that still need to be uncovered. We have recen
Externí odkaz:
https://doaj.org/article/da8e9fc5cf434bfc920c31fac94f0cdb
Autor:
Geanina Voicu, Daniela Rebleanu, Cristina Ana Constantinescu, Elena Valeria Fuior, Letitia Ciortan, Ionel Droc, Cristina Mariana Uritu, Mariana Pinteala, Ileana Manduteanu, Maya Simionescu, Manuela Calin
Publikováno v:
Pharmaceutics, Vol 12, Iss 6, p 507 (2020)
Calcific aortic valve disease (CAVD) is a progressive disorder that increases in prevalence with age. An important role in aortic valve calcification is played by valvular interstitial cells (VIC), that with age or in pathological conditions acquire
Externí odkaz:
https://doaj.org/article/302637c320594555b27075842a832b9a
Autor:
Letitia Ciortan, Ionel Droc, Elena Butoi, Andreea C. Mihaila, Sergiu Cecoltan, Mihaela Vadana, Monica Madalina Tucureanu, Ileana Manduteanu, Razvan Daniel Macarie
Publikováno v:
Journal of Cellular and Molecular Medicine
Calcific aortic valve disease (CAVD)—the most common valvular heart disease—is accelerated in diabetes and has no pharmacotherapy. Although it is known that early CAVD is associated with inflammation and osteogenesis, the molecular mechanisms inv