Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Leticia Vittone"'
Autor:
Jesica S Rodriguez, J Omar Velez Rueda, Margarita Salas, Romina Becerra, Mariano N Di Carlo, Matilde Said, Leticia Vittone, Gustavo Rinaldi, Enrique L Portiansky, Cecilia Mundiña-Weilenmann, Julieta Palomeque, Alicia Mattiazzi
Publikováno v:
PLoS ONE, Vol 9, Iss 4, p e96400 (2014)
UnlabelledSpontaneously hypertensive rat (SHR) constitutes a genetic model widely used to study the natural evolution of hypertensive heart disease. Ca²⁺-handling alterations are known to occur in SHR. However, the putative modifications of Ca²
Externí odkaz:
https://doaj.org/article/5cbb8f8fa17e45778c6cdaa14b0362ef
Autor:
Juan Ignacio Elio Mariángelo, Luis Gonano, Leticia Vittone, Cecilia Mundiña-Weilenmann, Matilde Said
Publikováno v:
Journal of Molecular and Cellular Cardiology. 173:28-29
Autor:
Juan Ignacio Elio, Mariángelo, Carlos Alfredo, Valverde, Leticia, Vittone, Matilde, Said, Cecilia, Mundiña-Weilenmann
Publikováno v:
European journal of pharmacology. 914
The function of endoplasmic reticulum (ER), a CaIn this study, we explored whether ER CaMechanical performance, cytosolic CaEmetine treatment precluded the I/R-induced increase in UPR signaling markers and improved the contractile recovery together w
Autor:
Noelia Lezcano, María Matilde Said, Leticia Vittone, Cecilia Mundiña-Weilenmann, Xander H.T. Wehrens, Juan Ignacio Elio Mariángelo
Publikováno v:
Journal of Molecular and Cellular Cardiology. 114:1-9
In cardiac muscle, signaling through cAMP governs many fundamental cellular functions, including contractility, relaxation and automatism. cAMP cascade leads to the activation of the classic protein kinase A but also to the stimulation of the recentl
Autor:
María Agustina Silvestri, Matilde Said, Margarita Ana Salas, Bárbara Soledad Román, Leticia Vittone, Cecilia Mundiña-Weilenmann, Juan Ignacio Elio Mariángelo
Publikováno v:
CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Aim: Myocardial ischemia/reperfusion (I/R) produces structural and functional alterations depending on the duration of ischemia. Brief ischemia followed by reperfusion causes reversible contractile dysfunction (stunned heart) but long -lasting ischem
Autor:
Mariano Nahuel Di Carlo, Leticia Vittone, Gina Sánchez, Paulina Donoso, Guillermo Raúl Schinella, Margarita Ana Salas, Xander H.T. Wehrens, Bárbara Soledad Román, Cecilia Mundiña-Weilenmann, Juan Ignacio Elio Mariángelo, Romina Valeria Becerra, María Matilde Said
Publikováno v:
SEDICI (UNLP)
Universidad Nacional de La Plata
instacron:UNLP
Universidad Nacional de La Plata
instacron:UNLP
Previous results from our laboratory showed that phosphorylation of ryanodine receptor 2 (RyR2) by Ca21 calmodulin-dependent kinase II (CaMKII) was a critical but not the unique event responsible for the production of reperfusion-induced arrhythmogen
Autor:
Jorge A. Negroni, Elena C. Lascano, Matilde Said, Cecilia Mundiña-Weilenmann, Leticia Vittone, Alicia Mattiazzi
Publikováno v:
Journal of Molecular and Cellular Cardiology. 60:172-183
Postacidotic arrhythmias have been associated to increased sarcoplasmic reticulum (SR) Ca2 + load and Ca2 +/calmodulin-dependent protein kinase II (CaMKII) activation. However, the molecular mechanisms underlying these arrhythmias are still unclear.
Autor:
Leda Giannuzzi, Ignacio Lucotti, Darío Andrinolo, Daniela Yazmine Sedan, Noelia Lezcano, Cecilia Mundiña-Weilenmann, Leticia Vittone
Publikováno v:
Journal of Biochemical and Molecular Toxicology. 26:131-138
Acute lethal cytotoxicity of microcystin-LR (MC-LR), a toxin produced by fresh-water cyanobacteria, has been attributed to protein phosphatases type 1 and type 2A (PP1/PP2A) inhibition and reactive oxygen species (ROS) generation. However, the effect
Autor:
Alicia Mattiazzi, Paulina Donoso, Leticia Vittone, Paola Ferrero, Gina Sánchez, Carlos Alfredo Valverde, Cecilia Mundiña-Weilenmann, María Matilde Said
Publikováno v:
Journal of Molecular and Cellular Cardiology. 43:281-291
We aimed to define the relative contribution of both PKA and Ca(2+)/calmodulin-dependent protein kinase II (CaMKII) cascades to the phosphorylation of RyR2 and the activity of the channel during beta-adrenergic receptor (betaAR) stimulation. Rat hear
Autor:
Pablo Stringa, Damian Sotelo, Enrique Correger, Josefina Marcos, Juan Manuel Lofeudo, Leticia Vittone, Graciela Laguens, M. Beldarrain
Publikováno v:
Intensive Care Medicine Experimental
Mechanical ventilation (MV) with high tidal volumes (Vt) leads to enormous biophysical lung damage, both in patients and in experimental animal models. From a biological point of view, however, the inflammatory response triggered by high Vt-MV and it