300. Epigenome-Wide Association Studies in Cases and Controls With High and Low Genetic Risk for Schizophrenia

Autor: Kira Höffler, Leticia Spindola, Anne-Kristin Stavrum, Ole A. Andreassen, Stephanie Le Hellard

Publikováno v: Biological Psychiatry. 93:S215

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::70b2b66f9fb7ec78dd565f540becde30
https://doi.org/10.1016/j.biopsych.2023.02.540

EPIGENOME-WIDE ASSOCIATION STUDIES IN CASES AND CONTROLS WITH HIGH AND LOW GENETIC RISK FOR SCHIZOPHRENIA

Autor: Kira Höffler, Leticia Spindola, Anne-Kristin Stavrum, Ole Andreassen, Stephanie Le Hellard

Publikováno v: European Neuropsychopharmacology. 63:e157

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d03c16343c4e984b829908d062cdb541
https://doi.org/10.1016/j.euroneuro.2022.07.288

Gene expression over the course of schizophrenia: from clinical high-risk for psychosis to chronic stages

Autor: Rodrigo A. Bressan, Hakon Hakonarson, Vanessa Kiyomi Ota, Marcos L. Santoro, Simone de Jong, Fernanda Talarico, Giovany Costa, Renata Pellegrino, Cristiano Noto, Gerome Breen, Sintia Iole Belangero, Leticia Spindola, Patricia Moretti, Ary Gadelha, Gabriela Xavier, Diogo Marques, Carolina Muniz Carvalho, Quirino Cordeiro, Jair de Jesus Mari

Publikováno v: npj Schizophrenia, Vol 5, Iss 1, Pp 1-6 (2019)
NPJ Schizophrenia

The study of patients with schizophrenia (SZ) at different clinical stages may help clarify what effects could be due to the disease itself, to the pharmacological treatment, or to the disease progression. We compared expression levels of targeted ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0175124703c0353de8d0f59bfa4d45e2
http://link.springer.com/article/10.1038/s41537-019-0073-0

Aging biological markers in a cohort of antipsychotic-naïve first-episode psychosis patients

Autor: Simone de Jong, Priscila Farias Tempaku, Sintia Iole Belangero, Marcos L. Santoro, Fernanda Talarico, Ary Gadelha, Gerome Breen, Quirino Cordeiro, Vanessa Kiyomi Ota, Pawan Kumar Maurya, Cristiano Noto, Patrícia S. Moretti, Leticia Spindola, Mariane N. Noto, Rodrigo A. Bressan, Gabriela Xavier

Publikováno v: Psychoneuroendocrinology. 132

Schizophrenia is a severe and multifactorial disorder with an unknown causative pathophysiology. Abnormalities in neurodevelopmental and aging processes have been reported. Relative telomere length (RTL) and DNA methylation age (DMA), well-known biom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67e7771089010312ce9f117af9321355
https://pubmed.ncbi.nlm.nih.gov/34271521

Effects of the brain-derived neurotropic factor variant Val66Met on cortical structure in late childhood and early adolescence

Autor: Andrea Parolin Jackowski, Sintia Iole Belangero, Rodrigo Grassi-Oliveira, Pedro Mario Pan, Euripedes Constantino Miguel, Elisa Brietzke, Luis Augusto Rohde, Renata Pellegrino, Vanessa Kiyomi Ota, Marco Antonio Gomes Del Aquilla, Célia Maria de Araújo, João Ricardo Sato, Walter Swardfager, Leticia Spindola, Hakon Hakonarson, Giovanni Abrahão Salum, Ary Gadelha, Felipe Almeida Picon, André Zugman, Rodrigo A. Bressan, Luciana Monteiro Moura, Edson Amaro

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Background The brain-derived neurotrophic factor (BDNF) Val66Met polymorphism (rs6265) has been associated with several neuropsychiatric disorders and regional structural brain changes in adults, but little is known about Val66Met's effect on brain m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5252fde7d41e9af07fdcf154a3ae8990
https://doi.org/10.1016/j.jpsychires.2017.12.008