Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Leticia Meneguello"'
Autor:
Silvia Peripolli, Leticia Meneguello, Chiara Perrod, Tanya Singh, Harshil Patel, Sazia T. Rahman, Koshiro Kiso, Peter Thorpe, Vincenzo Calvanese, Cosetta Bertoli, Robertus A. M. de Bruin
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-11 (2024)
Abstract Oncogene-induced replication stress is a crucial driver of genomic instability and one of the key events contributing to the onset and evolution of cancer. Despite its critical role in cancer, the mechanisms that generate oncogene-induced re
Externí odkaz:
https://doaj.org/article/3465e31efc2e4d63bc650aa1d9a692b2
Autor:
Silvia Peripolli, Tanya Singh, Harshil Patel, Leticia Meneguello, Koshiro Kiso, Peter Thorpe, Cosetta Bertoli, Robertus Antonius Maria de Bruin
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ea82ba7195f887fbe8058931cd493a37
https://doi.org/10.2139/ssrn.4026990
https://doi.org/10.2139/ssrn.4026990
Autor:
Gemma Wilson, Georgina Sava, Karla Vuina, Caroline Huard, Leticia Meneguello, Jasmin Coulombe-Huntington, Thierry Bertomeu, Rory Maizels, Josh Lauring, Mike Tyers, Simak Ali, Cosetta Bertoli, Robertus Antonius Maria de Bruin
Publikováno v:
SSRN Electronic Journal.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::55ef9e7a1aeb0b610d0854275c83bb26
https://doi.org/10.2139/ssrn.4236797
https://doi.org/10.2139/ssrn.4236797
Autor:
Marium Rana, Alessio Perotti, Lucy M Bisset, James D Smith, Emma Lamden, Zahra Khan, Media K Ismail, Katherine Ellis, Katie A Armstrong, Samantha L Hodder, Cosetta Bertoli, Leticia Meneguello, Robertus A M de Bruin, Joanna R Morris, Isolda Romero-Canelon, James H R Tucker, Nikolas J Hodges
Publikováno v:
Metallomics. 14
Pancreatic ductal adenocarcinoma (PDAC) is a disease that remains refractory to existing treatments including the nucleoside analogue gemcitabine. In the current study we demonstrate that an organometallic nucleoside analogue, the ferronucleoside 1-(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdb4f6adb1d75236ba05bfa5883d4608
https://doi.org/10.1093/mtomcs/mfac041
https://doi.org/10.1093/mtomcs/mfac041
Autor:
R. A. M. de Bruin, Caroline Huard, Gareth A. Wilson, G. Sava, Jasmin Coulombe-Huntington, J. Lauring, Leticia Meneguello, Simak Ali, Mike Tyers, Thierry Bertomeu, K. Vuina, R.J. Maizels, Cosetta Bertoli
CDK7 has a central role in promoting cellular proliferation, through the activation of the mitotic CDKs, and by driving global gene expression, through targeting RNA polymerase II. Several recently developed CDK7 inhibitors (CDK7i) have been shown to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ac1761e92b4b0cdeabd2beebdec6633b
https://doi.org/10.1101/2021.09.10.459733
https://doi.org/10.1101/2021.09.10.459733
Autor:
K. Kiso, Cosetta Bertoli, Leticia Meneguello, S. Peripolli, Peter H. Thorpe, R. A. M. de Bruin, Tanya Singh, Harshil Patel
Oncogene-induced replication stress is a major driver of genomic instability in cancer cells, with a central role in both cancer initiation and progression (1). Despite its critical role in cancer development, the mechanisms that lay at the basis of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::956ef569ce69ba9cb3ddb62056e27525
https://doi.org/10.1101/2021.07.25.453647
https://doi.org/10.1101/2021.07.25.453647
Autor:
Emma Lamben, Nikolas J. Hodges, Samantha L Hodder, Zahra Khan, Katie A Armstrong, Isolda Romero-Canelón, Alessio Perotti, Katherine Ellis, Leticia Meneguello, Joanna Morris, Robertus A.M. de Bruin, Cosetta Bertoli, James H. R. Tucker, Marium Rana, Lucy Bisset, James Smith, Media K. Ismail
Pancreatic ductal adenocarcinoma (PDAC) is a disease that remains largely refractory to existing treatments including the nucleoside analogue gemcitabine. In the current study we demonstrate that the ferronucleoside 1-(S,Rp) is cytotoxic in a panel o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d01a942d9440db9af4b83d0a02b5c5b7
https://doi.org/10.21203/rs.3.rs-741964/v1
https://doi.org/10.21203/rs.3.rs-741964/v1
Autor:
Sian Bray, Siân Culley, Anđela Šarić, Gautam Dey, Gabriel Tarrason Risa, Catherine Fan, Delyan R. Mutavchiev, Robertus A. M. de Bruin, Ricardo Henriques, Luca Pellegrini, Anne E. Hafner, Lena Harker-Kirschneck, Mairi L. Kilkenny, Fredrik Hurtig, Buzz Baum, Colin Davis, Dimitra Papatziamou, Ann-Christin Lindås, Ambrosius P. Snijders, Leticia Meneguello, André A. Pulschen, Nicholas P. Robinson, Peter Faull, Diorge P. Souza
Publikováno v:
Science
Proteasomal control of division in Archaea In eukaryotes, proteasome-mediated degradation of cell cycle factors triggers mitotic exit, DNA segregation, and cytokinesis, a process that culminates in abscission dependent on the protein ESCRT-III. By st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d492ef9cf289e7440840d230cd2d2a3
https://doi.org/10.1126/science.aaz2532
https://doi.org/10.1126/science.aaz2532
Autor:
Leticia Meneguello, Anna Livia Paraluppi, Ana Paula Guarnieri Bassi, Beatriz Cristina Pecoraro Sanches, Sandra Regina Ceccato-Antonini
Publikováno v:
Antonie van Leeuwenhoek. 111:1661-1672
The alcoholic fermentation for fuel ethanol production in Brazil occurs in the presence of several microorganisms present with the starter strain of Saccharomyces cerevisiae in sugarcane musts. It is expected that a multitude of microbial interaction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3bb4430cc8248d327856d443d33b80a
https://doi.org/10.1007/s10482-018-1056-2
https://doi.org/10.1007/s10482-018-1056-2
Autor:
Sian Bray, Colin Davis, Lena Harker-Kirschneck, Catherine Fan, Leticia Meneguello, Buzz Baum, Ricardo Henriques, Anđela Šarić, Dimitra Papatziamou, Gabriel Tarrason Risa, Anne E. Hafner, André A. Pulschen, Nicholas P. Robinson, Delyan R. Mutavchiev, Ann-Christin Lindås, Ambrosius P. Snijders, Luca Pellegrini, Peter Faull, Siân Culley, Mairi L. Kilkenny, Fredrik Hurtig, Gautam Dey, Robertus A. M. de Bruin
The archaeonSulfolobus acidocaldariusis a relative of eukaryotes known to progress orderly through its cell division cycle despite lacking obvious CDK/cyclin homologues. Here, in exploring the mechanisms underpinning archaeal cell division cycle cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65e06ee16a7981021df359fd654937e
https://doi.org/10.1101/774273
https://doi.org/10.1101/774273