Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Leticia M Toledo-Sherman"'
Autor:
Jeffrey L. Cummings, M. Isabel Gonzalez, Martyn C. Pritchard, Patrick C. May, Leticia M. Toledo-Sherman, Glenn A. Harris
Publikováno v:
Alzheimer’s Research & Therapy, Vol 15, Iss 1, Pp 1-17 (2023)
Abstract Tauopathies are a group of neurodegenerative disorders characterized by the aggregation of the microtubule-associated protein tau. Aggregates of misfolded tau protein are believed to be implicated in neuronal death, which leads to a range of
Externí odkaz:
https://doaj.org/article/de50d6618bc640deb5ed849724660489
Autor:
Keith A. Johnson, Michael Gold, Yakeel T. Quiroz, Sarah L. DeVos, Howard Feldman, Bradley T. Hyman, Susan Worley, Heather M. Snyder, Adam L. Boxer, Gil D. Rabinovici, Luc Buée, Pat Brannelly, Catherine J. Mummery, Irene Litvan, Leticia M Toledo-Sherman, James Mutamba, Kristin R. Wildsmith, Marc C. Patterson, Celeste M. Karch, Dirk Beher, Jean Pierre Brion, Maria C. Carrillo, Claire Sexton, Gaël Chételat, Martin Citron, Huw R. Morris, Alison Goate, Kristophe Diaz, Stacie Weninger, Amy Rommel, Diana R. Kerwin, Angela Cacace, Melanie B Shulman, Walter J. Koroshetz, Bess Frost
Publikováno v:
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021, Online ahead of print. ⟨10.1002/alz.12452⟩
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2021, Online ahead of print. ⟨10.1002/alz.12452⟩
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 18, iss 5
Alzheimer's & Dementia
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, 2021, Online ahead of print. ⟨10.1002/alz.12452⟩
Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Wiley, 2021, Online ahead of print. ⟨10.1002/alz.12452⟩
Alzheimer's & dementia : the journal of the Alzheimer's Association, vol 18, iss 5
Alzheimer's & Dementia
Studies supporting a strong association between tau deposition and neuronal loss, neurodegeneration, and cognitive decline have heightened the allure of tau and tau-related mechanisms as therapeutic targets. In February 2020, leading tau experts from
Autor:
Mark Rose, Odalys Gonzalez Paz, Giulio Auciello, Annalise Di Marco, Todd Herbst, Ignacio Muñoz-Sanjuán, Domenico Vignone, Edith Monteagudo, Vinod Khetarpal, Matteo Zini, Maria Rosaria Battista, Laura Orsatti, Vincenzo Summa, Celia Dominguez, Leticia M Toledo-Sherman, Ivan Fini, Antonella Cellucci
Publikováno v:
Molecular Pharmaceutics. 16:2069-2082
Huntington's disease (HD) is a neurodegenerative disease caused by polyglutamine expansion in the huntingtin protein. For drug candidates targeting HD, the ability to cross the blood-brain barrier (BBB) and reach the site of action in the central ner
Autor:
Leticia M, Toledo-Sherman, Deqi, Chen
Publikováno v:
Current opinion in drug discoverydevelopment. 5(3)
With the influx of targets generated by genomics and proteomics initiatives, a new drug discovery paradigm is emerging. Many companies are setting up target family platforms that tackle multiple targets and therapeutic areas simultaneously. Virtual s
Autor:
Irving Sucholeiki, Leticia M. Toledo-Sherman, Christopher M. Hosfield, Kelly Boutilier, Leroi V. DeSouza, David R. Stover
Publikováno v:
Molecular Diversity; 2004, Vol. 8 Issue 1, p9-19, 11p