Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Leticia Guadalupe Fragoso Morales"'
Autor:
Martha Cecilia Rosales Hernández, Marycruz Olvera-Valdez, Jazziel Velazquez Toledano, Jessica Elena Mendieta Wejebe, Leticia Guadalupe Fragoso Morales, Alejandro Cruz
Publikováno v:
Molecules, Vol 29, Iss 19, p 4780 (2024)
Despite the great effort that has gone into developing new molecules as multitarget compounds to treat Alzheimer’s disease (AD), none of these have been approved to treat this disease. Therefore, it will be interesting to determine whether benzazol
Externí odkaz:
https://doaj.org/article/c0e2c9f578a54044aac1f283d6c7b671
Evaluation of F3S4-m loaded liposomes as anti-AChE and its cytotoxic activity in PC12 and HMC3 cells
Autor:
Raúl Horacio Camarillo López, Leticia Guadalupe Fragoso Morales, Lilia Fernanda Delgado Cárdenas, Astrid Mayleth Rivera Antonio, Mónica Corea, Juan Israel Santos Macías, Marycruz Olvera Valdez, Martha Cecilia Rosales Hernández
Publikováno v:
SN Applied Sciences, Vol 5, Iss 12, Pp 1-19 (2023)
Abstract The current research discusses the loaded of F3S4-m compound reported with multitarget activity acting as an inhibitor of acetylcholinesterase (AChE), beta-secretase 1 (BACE1), and amyloid beta (Aβ) aggregation. Despite great effort has bee
Externí odkaz:
https://doaj.org/article/0e0fb91bb1da4c23853d928bda59b271
Autor:
Martha Cecilia Rosales-Hernández, Martiniano Bello, Jazziel Velazquez Toledano, Barbara Citlali Escudero Feregrino, José Correa Basurto, Leticia Guadalupe Fragoso Morales, Mónica Adriana Torres-Ramos
Publikováno v:
Journal of Biomolecular Structure and Dynamics. :1-16
The aryl hydrocarbon receptor (AhR) has broad biological functions when its ligands activate it; the non-binding interactions with AhR have not been fully elucidated due to the absence of a complete tridimensional (3D) structure. Therefore, utilizati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac565d907e1460c0db47f17e901b86c5
https://doi.org/10.1080/07391102.2023.2171132
https://doi.org/10.1080/07391102.2023.2171132
Publikováno v:
Antioxidants, Vol 10, Iss 2, p 218 (2021)
Alzheimer’s disease (AD) is one of the main human dementias around the world which is constantly increasing every year due to several factors (age, genetics, environment, etc.) and there are no prevention or treatment options to cure it. AD is char
Externí odkaz:
https://doaj.org/article/28958ea254614587819f5e7b15ea0a57
Autor:
Alma Alicia Ortiz-Morales, Juan Benjamín García-Vázquez, Manuel Jonathan Fragoso-Vázquez, Martha Cecilia Rosales-Hernández, Leticia Guadalupe Fragoso-Morales, Alan Rubén Estrada-Pérez, José Correa-Basurto
Publikováno v:
Scientific Reports. 13
Our work group designed and synthesized a promissory compound N-(2-hydroxyphenyl)-2-propylpentanamide (HO-AAVPA). The HO-AAVPA is a HDAC1 inhibitor and antiproliferative in cancer cell lines. However, HO-AAVPA is poor water solubility and enzymatical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1043642a0587f361fdc36cdb809857db
https://doi.org/10.1038/s41598-023-30144-7
https://doi.org/10.1038/s41598-023-30144-7
Autor:
Martha Cecilia Rosales Hernández, Leticia Guadalupe Fragoso Morales, José Correa Basurto, Marycruz Olvera Valdez, Efrén Venancio García Báez, Dania Guadalupe Román Vázquez, Ana Paola Anaya García, Alejandro Cruz
Publikováno v:
International Journal of Molecular Sciences; Volume 23; Issue 21; Pages: 12945
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder. Inhibiting acetylcholinesterase (AChE), amyloid beta (Aβ1-42) aggregation and avoiding the oxidative stress could prevent the progression of AD. Benzothiazole groups have shown
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4b73fbd4b3c500687bcae7e4ef163a5
https://doi.org/10.3390/ijms232112945
https://doi.org/10.3390/ijms232112945
Publikováno v:
Antioxidants
Antioxidants, Vol 10, Iss 218, p 218 (2021)
Antioxidants, Vol 10, Iss 218, p 218 (2021)
Alzheimer’s disease (AD) is one of the main human dementias around the world which is constantly increasing every year due to several factors (age, genetics, environment, etc.) and there are no prevention or treatment options to cure it. AD is char
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ab7b5384304436aeb0b893d334c210e
http://europepmc.org/articles/PMC7912941
http://europepmc.org/articles/PMC7912941
Autor:
Yudibeth Sixto-López, Martha Cecilia Rosales-Hernández, Edgar Abarca-Rojano, José Correa-Basurto, Arturo Contis-Montes de Oca, Ana María Correa-Basurto, Leticia Guadalupe Fragoso-Morales, Jessica Elena Mendieta-Wejebe
Publikováno v:
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5873, p 5873 (2020)
Volume 21
Issue 16
International Journal of Molecular Sciences, Vol 21, Iss 5873, p 5873 (2020)
N-(2&prime
hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) is a VPA derivative designed to be a histone deacetylase (HDAC) inhibitor. HO-AAVPA has better antiproliferative effect than VPA in cancer cell lines. Therefore, in this work, the inhibito
hydroxyphenyl)-2-propylpentanamide (HO-AAVPA) is a VPA derivative designed to be a histone deacetylase (HDAC) inhibitor. HO-AAVPA has better antiproliferative effect than VPA in cancer cell lines. Therefore, in this work, the inhibito
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd597b2df194d9e6931c5940c635fceb
https://doi.org/10.3390/ijms21165873
https://doi.org/10.3390/ijms21165873
Autor:
Brenda Chimal Vega, José Correa Basurto, Daniel Miguel Ángel Villalobos Acosta, Martha Cecilia Rosales Hernández, Leticia Guadalupe Fragoso Morales
Publikováno v:
International Journal of Molecular Sciences, Vol 19, Iss 8, p 2415 (2018)
International Journal of Molecular Sciences
International Journal of Molecular Sciences
The amyloid-β 1-42 (Aβ1-42) peptide is produced by proteolytic cleavage of the amyloid precursor protein (APP) by sequential reactions that are catalyzed by γ and β secretases. Aβ1-42, together with the Tau protein are two principal hallmarks of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7af7962e9c52320d137639d02e35179
http://www.mdpi.com/1422-0067/19/8/2415
http://www.mdpi.com/1422-0067/19/8/2415
Publikováno v:
Neuromethods ISBN: 9781493974030
Computational Modeling of Drugs Against Alzheimer’s Disease
Computational Modeling of Drugs Against Alzheimer’s Disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2eda17cda2663818904901d9c2d3d0ac
https://doi.org/10.1007/978-1-4939-7404-7
https://doi.org/10.1007/978-1-4939-7404-7
