Zobrazeno 1 - 10
of 230
pro vyhledávání: '"Leticia Fernandez"'
Autor:
Luisa Chocarro, Ester Blanco, Leticia Fernandez-Rubio, Maider Garnica, Miren Zuazo, Maria Jesus Garcia, Ana Bocanegra, Miriam Echaide, Colette Johnston, Carolyn J Edwards, James Legg, Andrew J Pierce, Hugo Arasanz, Gonzalo Fernandez-Hinojal, Ruth Vera, Karina Ausin, Enrique Santamaria, Joaquin Fernandez-Irigoyen, Grazyna Kochan, David Escors
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 8, Pp 1791-1816 (2024)
Abstract Many cancer patients do not benefit from PD-L1/PD-1 blockade immunotherapies. PD-1 and LAG-3 co-upregulation in T-cells is one of the major mechanisms of resistance by establishing a highly dysfunctional state in T-cells. To identify shared
Externí odkaz:
https://doaj.org/article/28ff1b0ab6c0455fbce072272578f5f4
Autor:
Leticia Fernandez-Friera, Rauf Nouni-Garcia, Concepcion Carratala-Munuera, Domingo Orozco-Beltran, Adriana Lopez-Pineda, Virtudes Pérez-Jover, Vicente Bertomeu-González, Pablo Martinez Perez, Alberto Cordero, Jose A Quesada, Jose Maria Castellano-Vazquez, Andreu Nolasco, Vicente F Gil Guillén, Alvaro Carbonell-Soliva, José Joaquin Mira-Solves, Jose Verdú Soriano, Julio Osende-Olea, Avelino Pereira-Expósito, Silvia Guillén-García, Eduardo Paya-Mora, Joaquina Díaz-Torres, Francisco González-Llopis
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Introduction and objectives Only about 50% of chronic patients in high-income countries adhere to their treatment. There are methods to measure medication adherence but none of them can be considered optimal. This study will aim to design and validat
Externí odkaz:
https://doaj.org/article/1f012c73bcb74a9b8f7e48c4c011a13a
Autor:
Leticia Fernandez-Friera, Jorge Solis, Joel M Gelfand, Carlota Abbad-Jaime de Aragón, Emilio Berna-Rico, María Asunción Ballester-Martinez, Pedro Jaén, Nehal N Mehta, Álvaro González-Cantero, María G Barderas
Publikováno v:
BMJ Open, Vol 13, Iss 9 (2023)
Introduction Life expectancy of patients with psoriasis is reduced by 4–5 years due to cardiovascular disease with an increased risk of myocardial infarction at an earlier age compared with the general population. This increased risk is independent
Externí odkaz:
https://doaj.org/article/5b02c8156c504e24a8d19be98785b887
Publikováno v:
Revista Brasileira de Cancerologia, Vol 40, Iss 3 (2023)
Se realizó un estúdio epidemiológico descriptivo del índice de asistencia de los pacientes remitidos por el estomatólogo hacia las consultas de cirugía máxilo facial y todos los pacientes examinados realmente en estas consultas de atención se
Externí odkaz:
https://doaj.org/article/871f6202edbe497484dc855eafccb8ad
Autor:
David Escors, Ana Bocanegra, Luisa Chocarro, Ester Blanco, Sergio Piñeiro-Hermida, Maider Garnica, Leticia Fernandez-Rubio, Ruth Vera, Hugo Arasanz, Grazyna Kochan
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13241 (2022)
PD-L1/PD-1 blockade immunotherapy has changed the therapeutic approaches for the treatment of many cancers. Nevertheless, the mechanisms underlying its efficacy or treatment failure are still unclear. Proficient systemic immunity seems to be a prereq
Externí odkaz:
https://doaj.org/article/9368ea6f30dc49aeb278620d161b8a4f
Autor:
Maider Garnica, Anna Aiello, Mattia Emanuela Ligotti, Giulia Accardi, Hugo Arasanz, Ana Bocanegra, Ester Blanco, Anna Calabrò, Luisa Chocarro, Miriam Echaide, Grazyna Kochan, Leticia Fernandez-Rubio, Pablo Ramos, Fanny Pojero, Nahid Zareian, Sergio Piñeiro-Hermida, Farzin Farzaneh, Giuseppina Candore, Calogero Caruso, David Escors
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9797 (2022)
The number of people that are 65 years old or older has been increasing due to the improvement in medicine and public health. However, this trend is not accompanied by an increase in quality of life, and this population is vulnerable to most illnesse
Externí odkaz:
https://doaj.org/article/8d072a5d97a54a0ca38c20e4d599476f
Autor:
Anna Aiello, Mattia Emanuela Ligotti, Maider Garnica, Giulia Accardi, Anna Calabrò, Fanny Pojero, Hugo Arasanz, Ana Bocanegra, Ester Blanco, Luisa Chocarro, Miriam Echaide, Leticia Fernandez-Rubio, Pablo Ramos, Sergio Piñeiro-Hermida, Grazyna Kochan, Nahid Zareian, Farzin Farzaneh, David Escors, Calogero Caruso, Giuseppina Candore
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 17, p 9880 (2022)
Vaccination, being able to prevent millions of cases of infectious diseases around the world every year, is the most effective medical intervention ever introduced. However, immunosenescence makes vaccines less effective in providing protection to ol
Externí odkaz:
https://doaj.org/article/1ed714b6d4e24c50b14514e85aef022e
Autor:
Bronwen Holloway, Harshitha Chandrasekar, Manju Purohit, Ashish Sharma, Aditya Mathur, Ashish KC, Leticia Fernandez-Carballo, Sabine Dittrich, Helena Hildenwall, Anna Bergström
Publikováno v:
Antibiotics, Vol 11, Iss 5, p 574 (2022)
Antibiotic resistance is a naturally occurring phenomenon, but the misuse and overuse of antibiotics is accelerating the process. This study aimed to quantify and compare antibiotic use before, during, and after seeking outpatient care for acute febr
Externí odkaz:
https://doaj.org/article/71bf407b800d408b91261e50c7291831
Autor:
Ester Blanco, Maria Ibañez-Vea, Carlos Hernandez, Lylia Drici, Xabier Martínez de Morentin, Maria Gato, Karina Ausin, Ana Bocanegra, Miren Zuazo, Luisa Chocarro, Hugo Arasanz, Gonzalo Fernandez-Hinojal, Joaquin Fernandez-Irigoyen, Cristian Smerdou, Maider Garnica, Miriam Echaide, Leticia Fernandez, Pilar Morente, Pablo Ramos-Castellanos, Diana Llopiz, Enrique Santamaria, Martin R. Larsen, David Escors, Grazyna Kochan
Publikováno v:
Journal of Personalized Medicine, Vol 11, Iss 6, p 542 (2021)
Monocytic and granulocytic myeloid-derived suppressor cells together with tumor-infiltrating macrophages constitute the main tumor-infiltrating immunosuppressive myeloid populations. Due to the phenotypic resemblance to conventional myeloid cells, th
Externí odkaz:
https://doaj.org/article/fb6b5e5b7e8a4077abb5519c8fe05237
Autor:
Cynthia M. Fehres, Nathalie O. van Uden, Nataliya G. Yeremenko, Leticia Fernandez, Gabriela Franco Salinas, Leonie M. van Duivenvoorde, Bertrand Huard, Jacques Morel, Hergen Spits, Michael Hahne, Dominique L. P. Baeten
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Regulatory B cells (Bregs) are immunosuppressive cells that modulate immune responses through multiple mechanisms. The signals required for the differentiation and activation of these cells remain still poorly understood. We have already shown that o
Externí odkaz:
https://doaj.org/article/c52da1b7f78341c89b1c697ffa766395