Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Leticia C. Fernández"'
Autor:
Sonia Veiga, Leticia C. Fernández, Emiliano Biasini, Susana B. Bravo, Manuel Martín-Pastor, Rafael López-Moreno, Yaiza B. Codeseira, Víctor M. Sánchez-Pedregal, Giovanni Spagnolli, Alba Iglesias, Hasier Eraña, Joaquín Castilla, Jesús R. Requena
PrPSc, the first described and most notorious prion, is the only protein known to cause epidemics of deadly disease. Its properties are encoded in its unique structure. Here we report a first solid state NMR study of a uniformly labelled (U-13C,15N)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8e4691ff55580ea9f0dee4a62d3a86f
https://doi.org/10.1101/2020.04.08.032839
https://doi.org/10.1101/2020.04.08.032839
Autor:
Silvia Biggi, Brunelli P, Gianluca Petris, Emiliano Biasini, Giovanni Spagnolli, Ines Mancini, Requena, Luise Linsenmeier, Hermann C. Altmeppen, Gasparotto D, Graziano Guella, Simone Orioli, Stefano Biressi, Maria Letizia Barreca, Beatrice Vignoli, Leticia C. Fernández, Giulia Maietta, Graziano Lolli, Marco Canossa, Alberto Boldrini, Michela Libergoli, Maria Pennuto, Manuel Pastor, Alan Ianeselli, Luca Terruzzi, Lorenzo Nl, Marta Rigoli, Tania Massignan, Laura Tosatto, Andrea Astolfi, Pietro Faccioli
Recent computational advancements in the simulation of biochemical processes allow investigating the mechanisms involved in protein regulation with realistic physics-based models, at an atomistic level of resolution. Using these techniques to study t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203dc461110274aa745667f9bc296858
https://doi.org/10.1101/2020.03.31.018069
https://doi.org/10.1101/2020.03.31.018069
Autor:
Giovanni Spagnolli, Tania Massignan, Andrea Astolfi, Silvia Biggi, Marta Rigoli, Paolo Brunelli, Michela Libergoli, Alan Ianeselli, Simone Orioli, Alberto Boldrini, Luca Terruzzi, Valerio Bonaldo, Giulia Maietta, Nuria L. Lorenzo, Leticia C. Fernandez, Yaiza B. Codeseira, Laura Tosatto, Luise Linsenmeier, Beatrice Vignoli, Gianluca Petris, Dino Gasparotto, Maria Pennuto, Graziano Guella, Marco Canossa, Hermann C. Altmeppen, Graziano Lolli, Stefano Biressi, Manuel M. Pastor, Jesús R. Requena, Ines Mancini, Maria L. Barreca, Pietro Faccioli, Emiliano Biasini
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-16 (2021)
Spagnolli, Massignan, Astolfi et al. design a new drug discovery approach, termed Pharmacological Protein Inactivation by Folding Intermediate Targeting, in which folding intermediates of disease-causing proteins are targeted. They test it on the cel
Externí odkaz:
https://doaj.org/article/e109df8e1973483785b0d57e6d79e2af
