Zobrazeno 1 - 10 of 126 pro vyhledávání: '"Leticia, Labriola"'
1
Akademický článek
Distinct photo-oxidation-induced cell death pathways lead to selective killing of human breast cancer cells
Autor: Ancély F. Dos Santos, Alex Inague, Gabriel S. Arini, Letícia F. Terra, Rosangela A. M. Wailemann, André C. Pimentel, Marcos Y. Yoshinaga, Ricardo R. Silva, Divinomar Severino, Daria Raquel Q. de Almeida, Vinícius M. Gomes, Alexandre Bruni-Cardoso, Walter R. Terra, Sayuri Miyamoto, Maurício S. Baptista, Leticia Labriola
Publikováno v: Cell Death and Disease, Vol 11, Iss 12, Pp 1-12 (2020)
Abstract Lack of effective treatments for aggressive breast cancer is still a major global health problem. We have previously reported that photodynamic therapy using methylene blue as photosensitizer (MB-PDT) massively kills metastatic human breast
Externí odkaz: https://doaj.org/article/d454c2ad322f485dbf8c42ec308495e3
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2
Akademický článek
HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells
Autor: Vinícius M. Gomes, Rosangela A. M. Wailemann, Gabriel S. Arini, Talita C. Oliveira, Daria R. Q. Almeida, Ancély F. dos Santos, Letícia F. Terra, Stephan Lortz, Leticia Labriola
Publikováno v: Cells, Vol 10, Iss 9, p 2178 (2021)
During type 1 diabetes mellitus (T1DM) development, beta-cells undergo intense endoplasmic reticulum (ER) stress that could result in apoptosis through the failure of adaptation to the unfolded protein response (UPR). Islet transplantation is conside
Externí odkaz: https://doaj.org/article/d69592ff84df4fdfb9374c470547755e
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3
Necroptosis activation is associated with greater methylene blue-photodynamic therapy-induced cytotoxicity in human pancreatic ductal adenocarcinoma cells
Autor: Daria R Q, de Almeida, Ancély F, Dos Santos, Rosangela A M, Wailemann, Letícia F, Terra, Vinícius M, Gomes, Gabriel S, Arini, Ester R M, Bertoldi, Eduardo M, Reis, Maurício S, Baptista, Leticia, Labriola
Publikováno v: Photochemicalphotobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology.
Pancreatic ductal adenocarcinomas (PDAC) are the fourth leading cause of death due to neoplasms. In view of the urgent need of effective treatments for PDAC, photodynamic therapy (PDT) appears as a promising alternative. However, its efficacy against
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::eece15e0774a2c736f3744e078782402
https://pubmed.ncbi.nlm.nih.gov/36495407
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6
HSPB1 influences mitochondrial respiration in ER-stressed beta cells
Autor: Vinícius M. Gomes, Livia Rosa-Fernandes, Martin R. Larsen, Leticia Labriola, Simon Ngao Mule, Rosangela A. M. Wailemann, Giuseppe Palmisano, Janaina Macedo-da-Silva
Publikováno v: Mule, S N, Gomes, V D M, Wailemann, R A M, Macedo-da-Silva, J, Rosa-Fernandes, L, Larsen, M R, Labriola, L & Palmisano, G 2021, ' HSPB1 influences mitochondrial respiration in ER-stressed beta cells ', Biochimica et Biophysica Acta-Proteins and Proteomics, vol. 1869, no. 9, 140680 . https://doi.org/10.1016/j.bbapap.2021.140680
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Beta-cell death and dysfunction are involved in the development of type 1 and 2 diabetes. ER-stress impairs beta-cells function resulting in pro-apoptotic stimuli that promote cell death. Hence, the identification of protective mechanisms in response
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac2af094cf0383058ff54ea2d48efc7c
https://portal.findresearcher.sdu.dk/da/publications/888f688e-0903-430f-a4cd-1b9691a077f1
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7
HSPB1 Is Essential for Inducing Resistance to Proteotoxic Stress in Beta-Cells
Autor: Daria Raquel Queiroz de Almeida, Stephan Lortz, Ancély Ferreira dos Santos, Gabriel S. Arini, Leticia Labriola, Talita C. Oliveira, Rosangela A. M. Wailemann, Vinícius M. Gomes, Letícia Ferreira Terra
Publikováno v: Cells; Volume 10; Issue 9; Pages: 2178
Cells, Vol 10, Iss 2178, p 2178 (2021)
Cells
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
During type 1 diabetes mellitus (T1DM) development, beta-cells undergo intense endoplasmic reticulum (ER) stress that could result in apoptosis through the failure of adaptation to the unfolded protein response (UPR). Islet transplantation is conside
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::846961cde56f7dd3c469e52dd635f550
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8
Fluence Rate Determines PDT Efficiency in Breast Cancer Cells Displaying Different GSH Levels
Autor: Leticia Labriola, Letícia Ferreira Terra, Daria Raquel Queiroz de Almeida, Rosangela A. M. Wailemann, Vinícius M. Gomes, Mauricio S. Baptista, Ancély Ferreira dos Santos, Felipe Gustavo Ravagnani, Gabriel S. Arini
Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Photodynamic therapy (PDT) appears as a promising alternative in the treatment of breast cancer since it can be highly effective in curing cancer while preserving normal tissue. However, predicting outcomes in PDT still constitutes a great challenge.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a19b42d392f7098b6be9618a00e97ef5
https://doi.org/10.1111/php.13182
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9
Elevated β-cell stress levels promote severe diabetes development in mice with MODY4
Autor: Bernadette M. Trojanowski, Heike Neubauer, Bernhard O. Boehm, Leticia Labriola, Thomas Wirth, Bernd Baumann, Martin Wagner, Heba Salem, Eric Simon, Rajkumar Dorajoo
Publikováno v: The Journal of Endocrinology
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Maturity-onset diabetes of the young (MODY) is a group of monogenetic forms of diabetes mellitus caused by mutations in genes regulating β-cell development and function. MODY represents a heterogeneous group of non-insulin-dependent diabetes arising
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17174ffc48e6cdab22d886c02245e1de
http://europepmc.org/articles/PMC6933809
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10
SARS-CoV-2 activates ER stress and Unfolded protein response
Autor: Oliveira Dbl, Dráulio Barros de Araújo, Claudia Blanes Angeli, Machado Rrg, Lucas Cardoso Lazari, E. L. Durigon, Giuseppe Palmisano, Rosa-Fernandes L, Arini Gs, Gomes VdM, Coutinho Jvp, Carsten Wrenger, de Souza Ee, Marinho Crf, Macedo-da-Silvia J, Leticia Labriola, dos Santos Af
Coronavirus disease-2019 (COVID-19) pandemic caused by the SARS-CoV-2 coronavirus infection is a major global public health concern affecting millions of people worldwide. The scientific community has joint efforts to provide effective and rapid solu
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5b595f0c90f8f51c63a2aaaa3b313aef
https://doi.org/10.1101/2021.06.21.449284
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