Proximity proteome mapping reveals PD-L1-dependent pathways disrupted by anti-PD-L1 antibody specifically in EGFR-mutant lung cancer cells.

Autor: Letian, Anudari^1,2 (AUTHOR), Lemma, Eyoel Yemanaberhan^1,3 (AUTHOR), Cavaliere, Paola¹ (AUTHOR), Dephoure, Noah^1,4 (AUTHOR), Altorki, Nasser K.^3,4,5 (AUTHOR), McGraw, Timothy E.^1,3,4,5 (AUTHOR) temcgraw@med.cornell.edu

Publikováno v: Cell Communication & Signaling. 3/13/2023, Vol. 21 Issue 1, p1-19. 19p.

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A secondary β-hydroxybutyrate metabolic pathway linked to energy balance.

Autor: Moya-Garzon MD; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Wu Tsai Human Performance Alliance, Stanford University, Stanford, CA, USA., Wang M; USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Li VL; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Chemistry, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Wu Tsai Human Performance Alliance, Stanford University, Stanford, CA, USA., Lyu X; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Wu Tsai Human Performance Alliance, Stanford University, Stanford, CA, USA., Wei W; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Tung AS; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Raun SH; Department of Biomedical Sciences, University of Copenhagen, Copenhagen, Denmark., Zhao M; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Coassolo L; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Islam H; School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada., Oliveira B; School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada., Dai Y; Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Spaas J; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Delgado-Gonzalez A; Department of Microbiology and Immunology, Stanford University, Stanford, CA, USA., Donoso K; Department of Urology, Stanford University School of Medicine, Stanford, CA, USA., Alvarez-Buylla A; Department of Biology, Stanford University, Stanford, CA, USA., Franco-Montalban F; Departamento de Química Farmacéutica y Orgánica, Universidad de Granada, Campus de Cartuja sn, 18011, Granada, Spain., Letian A; Department of Physiology, University of California, San Francisco, San Francisco, CA, USA., Ward C; Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Liu L; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA.; Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA., Svensson KJ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA.; Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, USA., Goldberg EL; Department of Physiology, University of California, San Francisco, San Francisco, CA, USA., Gardner CD; Stanford Prevention Research Center, Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Little JP; School of Health and Exercise Sciences, University of British Columbia, Kelowna, British Columbia, Canada., Banik SM; Department of Chemistry, Stanford University, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA., Xu Y; USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA., Long JZ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Sarafan ChEM-H, Stanford University, Stanford, CA, USA.; Stanford Diabetes Research Center, Stanford University, Stanford, CA, USA.; Wu Tsai Human Performance Alliance, Stanford University, Stanford, CA, USA.; The Phil & Penny Knight Initiative for Brain Resilience at the Wu Tsai Neurosciences Institute, Stanford University, Stanford, CA, USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Sep 09. Date of Electronic Publication: 2024 Sep 09.