Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Leta K. Nutt"'
Autor:
Sue-Hwa Lin, Leta K. Nutt, Mark A. Titus, Gary E. Gallick, Li-Yuan Yu-Lee, Daniel E. Frigo, Yu-Chen Lee, Song-Chang Lin, Chien-Jui Cheng, Guoyu Yu
Although emerging evidence suggests a potential role of calcium/calmodulin-dependent kinase II (CaMKII) in prostate cancer, its role in prostate cancer tumorigenesis is largely unknown. Here, we examine whether the acetyl CoA-CaMKII pathway, first de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61d97d6de91074e3f13598b00796eb1f
https://doi.org/10.1158/0008-5472.c.6509936
https://doi.org/10.1158/0008-5472.c.6509936
Autor:
Sue-Hwa Lin, Leta K. Nutt, Mark A. Titus, Gary E. Gallick, Li-Yuan Yu-Lee, Daniel E. Frigo, Yu-Chen Lee, Song-Chang Lin, Chien-Jui Cheng, Guoyu Yu
This file contains immunofluorescence of LNCaP, C4-2B4, PC3, and PC3-mm2 PCa cell lines (Supplementary Fig.S1); Immunohistochemistry for the expression of pCaMKII (T286) in specimens from human primary prostate tumor, lymph node metastasis, and bone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40416c7c104674bcc808a36ec4a004d3
https://doi.org/10.1158/0008-5472.22417769.v1
https://doi.org/10.1158/0008-5472.22417769.v1
Autor:
Leta K. Nutt, Yu Chen Lee, Guoyu Yu, Li Yuan Yu-Lee, Gary E. Gallick, Song Chang Lin, Daniel E. Frigo, Sue Hwa Lin, Chien Jui Cheng, Mark Titus
Publikováno v:
Cancer Research. 78:2490-2502
Although emerging evidence suggests a potential role of calcium/calmodulin-dependent kinase II (CaMKII) in prostate cancer, its role in prostate cancer tumorigenesis is largely unknown. Here, we examine whether the acetyl CoA-CaMKII pathway, first de
Autor:
Si Ing Chen, Francis McCoy, Roger J. Colbran, Rashid Darbandi, Anthony J. Baucum, Kelly A. Jones, Laura Eckard, Leta K. Nutt, Keela Dodd, Sue Hwa Lin, Jennifer A. Gibbons
Publikováno v:
Journal of Biological Chemistry. 288:8838-8848
The metabolism of the Xenopus laevis egg provides a cell survival signal. We found previously that increased carbon flux from glucose-6-phosphate (G6P) through the pentose phosphate pathway in egg extracts maintains NADPH levels and calcium/calmoduli
Autor:
Leta K, Nutt, Marisa R, Buchakjian, Eugene, Gan, Rashid, Darbandi, Sook-Young, Yoon, Judy Q, Wu, Yuko J, Miyamoto, Jennifer A, Gibbons, Jennifer A, Gibbon, Josh L, Andersen, Christopher D, Freel, Wanli, Tang, Changli, He, Manabu, Kurokawa, Yongjun, Wang, Seth S, Margolis, Rafael A, Fissore, Sally, Kornbluth
Publikováno v:
Developmental Cell. 16:856-866
Xenopus oocyte death is partly controlled by the apoptotic initiator, caspase-2. We reported previously that oocyte nutrient depletion activates caspase-2 upstream of mitochondrial cytochrome c release. Conversely, nutrient-replete oocytes inhibit ca
Autor:
Judy Qiju Wu, Christopher D. Freel, Jennifer A. Perry, Leta K. Nutt, Sally Kornbluth, Peter K. Jackson, David V. Hansen, Yanxiang Guo, Wanli Tang
Publikováno v:
Molecular Biology of the Cell. 19:3536-3543
The transition of oocytes from meiosis I (MI) to meiosis II (MII) requires partial cyclin B degradation to allow MI exit without S phase entry. Rapid reaccumulation of cyclin B allows direct progression into MII, producing a cytostatic factor (CSF)-a
Autor:
Sudhakar Jha, Chinweike Ukomadu, Takeshi Senga, James A. Wohlschlegel, Sally Kornbluth, Anindya Dutta, Leta K. Nutt, Suman Kumar Dhar, Wenge Zhu
Publikováno v:
Genes & Development. 21:2288-2299
The MCM2-7 helicase complex is loaded on DNA replication origins during the G1 phase of the cell cycle to license the origins for replication in S phase. How the initiator primase–polymerase complex, DNA polymerase α (pol α), is brought to the or
Autor:
Catherine E. Herman, Sally Kornbluth, William G. Dunphy, Leta K. Nutt, Jeffrey C. Rathmell, Seth S. Margolis, Mette V. Jensen
Publikováno v:
Cell. 123(1):89-103
Summary Vertebrate female reproduction is limited by the oocyte stockpiles acquired during embryonic development. These are gradually depleted over the organism's lifetime through the process of apoptosis. The timer that triggers this cell death is y
Autor:
Vladimir Gogvadze, David J. McConkey, Wanlaya Uthaisang, Sten Orrenius, Leta K. Nutt, Banafsheh Mirnikjoo
Publikováno v:
Cancer Biology & Therapy. 4:465-473
Arsenic trioxide is a potent chemotherapeutic agent that selectively triggers apoptosis in tumor cells. Previous studies have demonstrated that arsenicals cause direct damage to mitochondria, but it is not clear that these effects initiate apoptosis.
Autor:
Roger G. O'Neil, David J. McConkey, Abujiang Pataer, Jack A. Roth, Leta K. Nutt, Bingliang Fang, Stephen G. Swisher, Joya Chandra
Publikováno v:
Journal of Biological Chemistry. 277:20301-20308
Previous studies have demonstrated that Ca(2+) is released from the endoplasmic reticulum (ER) in some models of apoptosis, but the mechanisms involved and the functional significance remain obscure. We confirmed that apoptosis induced by some (but n