Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Letícia C. Giacomin"'
Autor:
Diego S. Padilha, Jackson A. L. C. Resende, Alexandre B. Rocha, Marciela Scarpellini, Letícia C. Giacomin, Marcos D. Pereira, Frederico A.V. Castro, Yan F. Santos
Publikováno v:
Polyhedron. 123:480-489
Cisplatin and its analogues are some of the most widely used anticancer drugs. However, toxicity and resistance have limited their use, and gallium compounds have emerged as an alternative, due to their remarkable antitumor activity and low toxicity.
Autor:
Roberto B. Faria, Frederico A.V. Castro, Amanda dos S. Cavalcanti, Marcos D. Pereira, Marciela Scarpellini, Letícia C. Giacomin, Bianca M. Pires, Adailton J. Bortoluzzi
Publikováno v:
Journal of Inorganic Biochemistry. 157:104-113
Cobalt(III) complexes are well-suited systems for cytotoxic drug release under hypoxic conditions. Here, we investigate the effect of cytotoxic azide release by cobalt-containing carrier-prototypes for antitumoral prodrugs. In addition, we study the