Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Letícia Aragão-Santiago"'
Autor:
Güínever Eustáquio do Império, Isalira Peroba Ramos, Letícia Aragão Santiago, Guilherme Faria Pereira, Norma Aparecida dos Santos Almeida, Cesar Seigi Fuziwara, Carmen C. Pazos-Moura, Edna Teruko Kimura, Emerson Lopes Olivares, Tania Maria Ortiga-Carvalho
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 2, Pp 477-490 (2015)
Background/Aims: Thyroid hormone (TH) signalling is critical for heart function. The heart expresses thyroid hormone receptors (THRs); THRα1 and THRβ1. We aimed to investigate the regulation mechanisms of the THRβ isoform, its association with gen
Externí odkaz:
https://doaj.org/article/8399043f6fd2466a807e84e8b828a7df
Autor:
Verena Krähling, Stephanie Erbar, Alexandra Kupke, Sara S. Nogueira, Kerstin C. Walzer, Hendrik Berger, Erik Dietzel, Sandro Halwe, Cornelius Rohde, Lucie Sauerhering, Letícia Aragão-Santiago, Jorge Moreno Herrero, Sonja Witzel, Heinrich Haas, Stephan Becker, Ugur Sahin
Publikováno v:
Molecular therapy : the journal of the American Society of Gene Therapy.
Emerging and re-emerging viruses, such as Zaire Ebola virus (EBOV), pose a global threat and require immediate countermeasures, including the rapid development of effective vaccines that are easy to manufacture. Synthetic self-amplifying RNAs (saRNAs
Autor:
Saadia Kerdine-Römer, Letícia Aragão Santiago, Hervé Hillaireau, Nicolas Tsapis, Juliette Vergnaud, Nadège Grabowski, Elias Fattal, Marc Pallardy
Publikováno v:
International Journal of Pharmaceutics. 454:686-694
In vitro cytotoxicity and inflammatory response following exposure to nanoparticles (NPs) made of poly(lactide-co-glycolide) (PLGA) have been investigated on A549 human lung epithelial cells. Three different PLGA NPs (230 nm) were obtained using diff
Autor:
Letícia Aragão Santiago, Guinever E. Imperio, Larissa C. Faustino, Fredric E. Wondisford, Flavia Fonseca Bloise, Carmen C. Pazos-Moura, Tania M. Ortiga-Carvalho, Guilherme Faria Pereira
Publikováno v:
Life sciences. 170
Aims To understand how thyroid hormone (TH) regulates tissue-specific gene expression in patients with the syndrome of resistance to TH (RTHβ), we used a mouse model that replicates the human RTHβ, specifically the ∆ 337T mutation in the thyroid
Autor:
Tania M. Ortiga-Carvalho, Aline Cordeiro, Fredric E. Wondisford, Patricia Cristina Lisboa, Diana Aragão Santiago, Letícia Aragão Santiago, Larissa C. Faustino, Carmen C. Pazos-Moura
Publikováno v:
Journal of Endocrinology. 211:39-46
Mice bearing the genomic mutation Δ337T on the thyroid hormone receptor β (TRβ) gene present the classical signs of resistance to thyroid hormone (TH), with high serum TH and TSH. This mutant TR is unable to bind TH, remains constitutively bound t
Autor:
Tania M. Ortiga-Carvalho, Aniket Sidhaye, Letícia Aragão Santiago, Danielle S. Machado, Fredric E. Wondisford, Maria Izabel Chiamolera, Amin Sabet
Publikováno v:
Proceedings of the National Academy of Sciences. 106:9441-9446
Resistance to thyroid hormone (RTH) is most often due to point mutations in the β-isoform of the thyroid hormone (TH) receptor (TR-β). The majority of mutations involve the ligand-binding domain, where they block TH binding and receptor function on
Autor:
Edna Teruko Kimura, Letícia Aragão Santiago, Guilherme Faria Pereira, Tania M. Ortiga-Carvalho, Norma Aparecida dos Santos Almeida, Isalira Peroba Ramos, Cesar Seigi Fuziwara, Carmen C. Pazos-Moura, Emerson L. Olivares, Guinever E. Imperio
Publikováno v:
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Cellular Physiology and Biochemistry, Vol 37, Iss 2, Pp 477-490 (2015)
Universidade de São Paulo (USP)
instacron:USP
Cellular Physiology and Biochemistry, Vol 37, Iss 2, Pp 477-490 (2015)
Background/Aims: Thyroid hormone (TH) signalling is critical for heart function. The heart expresses thyroid hormone receptors (THRs); THRα1 and THRβ1. We aimed to investigate the regulation mechanisms of the THRβ isoform, its association with gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c69ea4673847d1ed6914fea685bdb341
Autor:
Cesar Seigi Fuziwara, Tania M. Ortiga-Carvalho, Edna Teruko Kimura, Letícia Aragão Santiago, Norma Aparecida dos Santos Almeida, Emerson L. Olivares, Isalira Peroba Ramos de Goes Freitas, Guinever E. Imperio, Guilherme Faria Pereira
Publikováno v:
ResearcherID
Autor:
Marcelo M. Morales, Letícia Aragão Santiago, Aline Cristina Gomes, Debora S. Ornellas, Horacio J. Novaira, Tania M. Ortiga-Carvalho
Publikováno v:
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology. 26(2)
Background/Aims: Mutations in the thyroid hormone receptor β (TR-β) gene result in resistance to thyroid hormone (RTH). Mutation Δ337T in the TR-β gene has been shown to have the characteristics of RTH syndrome in mice. The aim of this work was t
Thyroid Hormone Action Is Required for Normal Cone Opsin Expression during Mouse Retinal Development
Autor:
Danielle S. Machado, Jan Nora Hokoç, Tania M. Ortiga-Carvalho, Dora Fix Ventura, Diana Aragão Santiago, Cristiano N. Pessôa, Letícia Aragão Santiago, Carmen C. Pazos-Moura, Patrícia F. Gardino, Fernando Allan de Farias Rocha, Fredric E. Wondisford
Publikováno v:
Investigative Opthalmology & Visual Science. 49:2039
PURPOSE. The expression of S- and M-opsins in the murine retina is altered in different transgenic mouse models with mutations in the thyroid hormone receptor (TR)- gene, demonstrating an important role of thyroid hormone (TH) in retinal development.