Výsledky vyhledávání - "Leszek Szmigiero"

Akademický článek

The Effect of Occasional Alcohol Drinking on Semen Quality and Sperm Morphology among Young and Healthy Polish Men

Autor: Felicja Lwow, Marek Medraś, Małgorzata Słowińska-Lisowska, Paweł Jóźków, Leszek Szmigiero

Publikováno v: Journal of Men's Health, Vol 13, Iss 2 (2017)

ABSTRACT Background: Ethanol (EtOH) is an agent that seems to exert an especially harmful effect on male fertility. The impact of high EtOH intake on fertility was demonstrated in numerous researches, with data suggesting that this effect may have

Externí odkaz: https://doaj.org/article/04e8c56680e44b6a8258357f369b68c5

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New Look on 3-Hydroxyiminoflavanone and Its Palladium(II) Complex: Crystallographic and Spectroscopic Studies, Theoretical Calculations and Cytotoxic Activity

Autor: Maria Kasprzak, Małgorzata Fabijańska, Lilianna Chęcińska, Leszek Szmigiero, Justyn Ochocki

Publikováno v: Molecules, Vol 21, Iss 4, p 455 (2016)

This work presents the synthesis, spectroscopic properties and single-crystal X-ray examination of the structure of 3-hydroxyiminoflavanone and its palladium complex. It presents the results of NMR (Nuclear Magnetic Resonance) spectroscopy, electron-

Externí odkaz: https://doaj.org/article/ba60fde676464d499f4cddb3105d6b11

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SIRT1 as a Therapeutic Target in Diabetic Complications

Autor: Leszek Szmigiero, Agnieszka Sliwinska, Janusz Szemraj, Justyna Strycharz, Józef Drzewoski, Zaneta Rygielska, Ewa Swiderska

Publikováno v: Current Medicinal Chemistry. 25:1002-1035

Background: Sirtuin1 is an epigenetic enzyme involved in histone and nonhistone protein deacetylation. It acts primarily as a metabolic sensor, which responses to changing energy status by deacetylating crucial transcription factors and cofactors. In

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fa0fa03346f6bf89406156a0f9156aa
https://doi.org/10.2174/0929867324666171107103114

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Lipid accumulation product (LAP) as a criterion for the identification of the healthy obesity phenotype in postmenopausal women

Autor: Andrzej Milewicz, Leszek Szmigiero, Diana Jędrzejuk, Felicja Lwow

Publikováno v: Experimental Gerontology. 82:81-87

Obesity and its complications constitute a major health problem in postmenopausal women. The identification of the obesity phenotype, especially that of metabolically healthy obese (MHO) patients, is a necessary part of obesity treatment protocols. T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf9cd34a4bbe5534cc46fff7cf3dcf6
https://doi.org/10.1016/j.exger.2016.06.007

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Subcellular localization of anthracyclines in cultured rat cardiomyoblasts as possible predictors of cardiotoxicity

Autor: Krzysztof Kik, Kazimierz Studzian, Malgorzata Strek, Leszek Szmigiero, Irena Oszczapowicz, Malgorzata Lukawska

Publikováno v: Investigational New Drugs

SummaryIn this study, we compared the cellular uptake, intracellular localization and cytotoxicity of two groups of anthracycline derivatives in cultured H9c2(2-1) rat cardiomyoblasts. The first group consisted of doxorubicin (DOX) and two of its der

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa830592d664eb844d52bc188955a14a
http://europepmc.org/articles/PMC4768221

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Proapoptotic activity in vitro of two novel ruthenium(II) complexes with flavanone-based ligands that overcome cisplatin resistance in human bladder carcinoma cells

Autor: Leszek Szmigiero, Justyn Ochocki, Maria M. Kasprzak, Elzbieta Zyner

Publikováno v: Journal of Inorganic Biochemistry. 105:518-524

In this study we examined their proapoptotic activity of cis -dichloridobis(3-imino-2-methoxyflavanone)ruthenium(II) 3H 2 O ( 1 ) and cis -dichloridobis(3-imino-2-ethoxyflavanone)ruthenium(II) 2H 2 O ( 2 ) towards human bladder carcinoma cell line EJ

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f47f857d11d51db2decfe7f9cf25f9d
https://doi.org/10.1016/j.jinorgbio.2010.12.013

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Cytotoxic activity and chemical reactivity of cis-platinum(II) and trans-palladium(II) complexes with diethyl (pyridinylmethyl)phosphates

Autor: Leszek Szmigiero, Urszula Kalinowska-Lis, Kazimierz Studzian, Justyn Ochocki

Publikováno v: European Journal of Medicinal Chemistry. 44:660-664

A series of square-planar platinum(II) and palladium(II) complexes of the formula cis-[PtCl2L2] and trans-[PdCl2L2] [L stands for diethyl (pyridin-2-ylmethyl)phosphate (2-pmOpe) or diethyl (pyridin-3-ylmethyl)phosphate (3-pmOpe) or diethyl (pyridin-4

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f439f100ffda5bcc5890da48c82fb746
https://doi.org/10.1016/j.ejmech.2008.05.014

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The quality of semen among a sample of young, healthy men from Lower Silesia (AndroLS)

Autor: Felicja Lwow, Leszek Szmigiero, Marek Mędraś, Małgorzata Słowińska-Lisowska, Paweł Jóźków, Aleksandra Zagrodna, Ewa Zagocka

Publikováno v: Endokrynologia Polska.

Introduction: Contrary to other parts of the continent, little information is available regarding semen quality among subjects from central and eastern Europe. Material and methods: We evaluated semen profiles among a sample of men from an industrial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba255062b24fa38370c54f5e38a7530
https://doi.org/10.5603/ep.a2017.0056

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