Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Leszek Szablewski"'
Autor:
Leszek Szablewski
Publikováno v:
Current Oncology, Vol 31, Iss 2, Pp 998-1027 (2024)
Insulin resistance, also known as impaired insulin sensitivity, is the result of a decreased reaction of insulin signaling to blood glucose levels. This state is observed when muscle cells, adipose tissue, and liver cells, improperly respond to a par
Externí odkaz:
https://doaj.org/article/d08ef5fb699e49bdb00555599ad0f2a8
Autor:
Monika Pliszka, Leszek Szablewski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 13, p 7476 (2024)
Cancer is one of the major causes of mortality and is the second leading cause of death. Diabetes mellitus is a serious and growing problem worldwide, and its prevalence continues to grow; it is the 12th leading cause of death. An association between
Externí odkaz:
https://doaj.org/article/3a1705b3970b4f27834c1e80d20ad0b0
Autor:
Leszek Szablewski
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 4, p 2397 (2024)
Insulin is a polypeptide hormone synthesized and secreted by pancreatic β-cells. It plays an important role as a metabolic hormone. Insulin influences the metabolism of glucose, regulating plasma glucose levels and stimulating glucose storage in org
Externí odkaz:
https://doaj.org/article/53992b5574f749e09eafe73e629a98b8
Autor:
Leszek Szablewski
Publikováno v:
Oncology Reviews, Vol 16, Iss 1 (2022)
Glucose is a main metabolic substrate, which plays a role as a source of energy and a substrate in several processes. Cell membrane is lipophilic, whereas monosaccharides are hydrophilic. Therefore, lipid bilayer is impermeable for these substances a
Externí odkaz:
https://doaj.org/article/5d1d9826da554d57affcb4606b8da8bf
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13522 (2021)
The kidney plays an important role in glucose homeostasis by releasing glucose into the blood stream to prevent hypoglycemia. It is also responsible for the filtration and subsequent reabsorption or excretion of glucose. As glucose is hydrophilic and
Externí odkaz:
https://doaj.org/article/07b91e9c2f5d4ace8169bc7422f48505
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 24, p 13440 (2021)
The majority of the epithelial surfaces of our body, and the digestive tract, respiratory and urogenital systems, are colonized by a vast number of bacteria, archaea, fungi, protozoans, and viruses. These microbiota, particularly those of the intesti
Externí odkaz:
https://doaj.org/article/b641ae7b1d2a4ab9aaa9174b7ff06ca7
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 18, p 9987 (2021)
Insulin plays a range of roles as an anabolic hormone in peripheral tissues. It regulates glucose metabolism, stimulates glucose transport into cells and suppresses hepatic glucose production. Insulin influences cell growth, differentiation and prote
Externí odkaz:
https://doaj.org/article/f16e355c73a8405aa995530184b8d6a7
Autor:
Monika Pliszka, Leszek Szablewski
Publikováno v:
Cancers, Vol 13, Iss 16, p 4184 (2021)
Tumor growth causes cancer cells to become hypoxic. A hypoxic condition is a hallmark of cancer. Metabolism of cancer cells differs from metabolism of normal cells. Cancer cells prefer the process of glycolysis as a source of ATP. Process of glycolys
Externí odkaz:
https://doaj.org/article/eacf9defd7d7469f93857740727cd224
Autor:
Leszek Szablewski
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 15, p 8142 (2021)
The most common cause of dementia, especially in elderly people, is Alzheimer’s disease (AD), with aging as its main risk factor. AD is a multifactorial neurodegenerative disease. There are several factors increasing the risk of AD development. One
Externí odkaz:
https://doaj.org/article/c4cfaacbecd54aa6b3a8fad1c711f550
Autor:
Leszek Szablewski
Publikováno v:
Journal of Biomedical Science, Vol 24, Iss 1, Pp 1-12 (2017)
Abstract Kidneys play an important role in glucose homeostasis. Renal gluconeogenesis prevents hypoglycemia by releasing glucose into the blood stream. Glucose homeostasis is also due, in part, to reabsorption and excretion of hexose in the kidney. L
Externí odkaz:
https://doaj.org/article/8d1cc9f3ae2a415895c4e4b1ee51add0