Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Leszek Michalak"'
Autor:
Leszek Michalak, John Christian Gaby, Leidy Lagos, Sabina Leanti La Rosa, Torgeir R. Hvidsten, Catherine Tétard-Jones, William G. T. Willats, Nicolas Terrapon, Vincent Lombard, Bernard Henrissat, Johannes Dröge, Magnus Øverlie Arntzen, Live Heldal Hagen, Margareth Øverland, Phillip B. Pope, Bjørge Westereng
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Here, the authors tailor an acetylated galactoglucomannan (AcGGM) fibre from spruce wood to specifically enrich Roseburia and Faecalibacterium - beneficial species which have the enzymatic machinery to breakdown the fibre and generate butyrate. They
Externí odkaz:
https://doaj.org/article/6e5fccddd70b4f2492963a10a80b13c2
Autor:
Lars J. Lindstad, Galiana Lo, Shaun Leivers, Zijia Lu, Leszek Michalak, Gabriel V. Pereira, Åsmund K. Røhr, Eric C. Martens, Lauren S. McKee, Petra Louis, Sylvia H. Duncan, Bjørge Westereng, Phillip B. Pope, Sabina Leanti La Rosa
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
Commensal butyrate-producing bacteria belonging to the Firmicutes
Externí odkaz:
https://doaj.org/article/92fb32159fb8474db28db2b9d8e1d9c6
Autor:
Sabina Leanti La Rosa, Maria Louise Leth, Leszek Michalak, Morten Ejby Hansen, Nicholas A. Pudlo, Robert Glowacki, Gabriel Pereira, Christopher T. Workman, Magnus Ø. Arntzen, Phillip B. Pope, Eric C. Martens, Maher Abou Hachem, Bjørge Westereng
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
How dietary β-mannans are utilized by gut Gram-positive bacteria is unclear. Here, the authors uncover the enzymatic pathway for β-mannan metabolism in Roseburia intestinalis and show that these polysaccharides promote beneficial gut bacteria, high
Externí odkaz:
https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b8
Publikováno v:
Biotechnology for Biofuels, Vol 11, Iss 1, Pp 1-12 (2018)
Abstract Background Acetylated galactoglucomannan (AcGGM) is a complex hemicellulose found in softwoods such as Norway spruce (Picea abies). AcGGM has a large potential as a biorefinery feedstock and source of oligosaccharides for high-value industri
Externí odkaz:
https://doaj.org/article/e035ef5d8c03433db42c92d1a4fb70bc
Autor:
Åsmund K. Røhr, Phillip B. Pope, Sabina Leanti La Rosa, Petra Louis, Gabriel V. Pereira, Zijia Lu, Sylvia H. Duncan, Lauren S. McKee, Shaun Leivers, Eric C. Martens, Bjørge Westereng, Leszek Michalak, Lars Jordhøy Lindstad, Galiana Lo
Publikováno v:
mBio, Vol 12, Iss 3 (2021)
mBio
mBio
β-Mannans are hemicelluloses that are abundant in modern diets as components in seed endosperms and common additives in processed food. Currently, the collective understanding of β-mannan saccharification in the human colon is limited to a few keys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9dbecb2cc04f530d7fa660496eedeb3d
https://journals.asm.org/doi/10.1128/mBio.03628-20
https://journals.asm.org/doi/10.1128/mBio.03628-20
Autor:
Bjørge Westereng, Morten Ejby Hansen, Nicholas A. Pudlo, Magnus Ø. Arntzen, Maria Louise Leth, Maher Abou Hachem, Eric C. Martens, Robert W. P. Glowacki, Phillip B. Pope, Leszek Michalak, Gabriel V. Pereira, Christopher T. Workman, Sabina Leanti La Rosa
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
Nature Communications
La Rosa, S L, Leth, M L, Michalak, L, Hansen, M E, Pudlo, N A, Glowacki, R, Pereira, G, Workman, C T, Arntzen, M, Pope, P B, Martens, E C, Hachem, M A & Westereng, B 2019, ' The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans ', Nature Communications, vol. 10, no. 1, 905 . https://doi.org/10.1038/s41467-019-08812-y
Nature Communications
La Rosa, S L, Leth, M L, Michalak, L, Hansen, M E, Pudlo, N A, Glowacki, R, Pereira, G, Workman, C T, Arntzen, M, Pope, P B, Martens, E C, Hachem, M A & Westereng, B 2019, ' The human gut Firmicute Roseburia intestinalis is a primary degrader of dietary β-mannans ', Nature Communications, vol. 10, no. 1, 905 . https://doi.org/10.1038/s41467-019-08812-y
β-Mannans are plant cell wall polysaccharides that are commonly found in human diets. However, a mechanistic understanding into the key populations that degrade this glycan is absent, especially for the dominant Firmicutes phylum. Here, we show that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::167094d7e33503cf8923cf67a1f7f682
https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b8
https://doaj.org/article/2eb37bf7353c4750bb4b7813444df9b8
Publikováno v:
CHI Extended Abstracts
This study tested two different approaches for adding an explainability feature to the implementation of a legal text summarization solution based on a Deep Learning (DL) model. Both approaches aimed to show the reviewers where the summary originated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bcf733e5e5797e44ed31afa2e0e52c35
https://doi.org/10.1145/3411763.3443441
https://doi.org/10.1145/3411763.3443441
Autor:
Sylvia H. Duncan, Bjørge Westereng, Zijia Lu, Galiana Lo, Eric C. Martens, Phillip B. Pope, Lars Jordhøy Lindstad, Shaun Leivers, Lauren S. McKee, Sabina Leanti La Rosa, Leszek Michalak, Gabriel V. Pereira, Åsmund K. Røhr
β-Mannans are hemicelluloses that are abundant in modern diets as components in seed endosperms and common additives in processed food. Currently, the collective understanding of β-mannan saccharification in the human colon is limited to a few keys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af95d92fb076a0c2612cacd789808533
https://doi.org/10.1101/2020.12.23.424282
https://doi.org/10.1101/2020.12.23.424282
Autor:
Leszek Michalak, Åsmund K. Røhr, Bjørge Westereng, Finn Lillelund Aachmann, Shaun Leivers, Lars Jordhøy Lindstad, Sabina Leanti La Rosa
Publikováno v:
Proc Natl Acad Sci U S A
β-Mannans and xylans are important components of the plant cell wall and they are acetylated to be protected from degradation by glycoside hydrolases. β-Mannans are widely present in human and animal diets as fiber from leguminous plants and as thi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b5853cf4d06da3bc468a902b2c93d14
https://europepmc.org/articles/PMC7132267/
https://europepmc.org/articles/PMC7132267/
Autor:
Johannes Dröge, Catherine Tétard-Jones, Sabina Leanti La Rosa, Magnus Ø. Arntzen, Nicolas Terrapon, John Christian Gaby, Torgeir R. Hvidsten, Live Heldal Hagen, Margareth Øverland, Leszek Michalak, Bernard Henrissat, Bjørge Westereng, William G.T. Willats, Vincent Lombard, Phillip B. Pope, Leidy Lagos
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-19585-0⟩
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-19585-0⟩
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Nature Communications, Nature Publishing Group, 2020, 11 (1), ⟨10.1038/s41467-020-19585-0⟩
Nature Communications, 2020, 11 (1), ⟨10.1038/s41467-020-19585-0⟩
Beneficial modulation of the gut microbiome has high-impact implications not only in humans, but also in livestock that sustain our current societal needs. In this context, we have tailored an acetylated galactoglucomannan (AcGGM) fibre to match uniq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2729ee6b6025137ab4c87f8e73cb8964
https://hdl.handle.net/11250/2756608
https://hdl.handle.net/11250/2756608