Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Leszek Kotula"'
Autor:
Max Petersen, Anna Chorzalska, Makayla Pardo, Anaelena Rodriguez, John Morgan, Nagib Ahsan, Ting C. Zhao, Olin Liang, Leszek Kotula, Paul Bertone, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology, Vol 17, Iss 11, Pp 2356-2379 (2023)
Dysregulation of the adaptor protein Abelson interactor 1 (ABI1) is linked to malignant transformation. To interrogate the role of ABI1 in cancer development, we mapped the ABI1 interactome using proximity‐dependent labeling (PDL) with biotin follo
Externí odkaz:
https://doaj.org/article/9feb2424ca384d45925ebb57c2e9eae4
Autor:
Angelina Regua, Csaba Papp, Andre Grageda, Baylee A. Porter, Tiffany Caza, Isabelle Bichindaritz, Mira Krendel, Abirami Sivapiragasam, Gennady Bratslavsky, Vladimir A. Kuznetsov, Leszek Kotula
Publikováno v:
Molecular Oncology, Vol 16, Iss 14, Pp 2632-2657 (2022)
Despite the current standard of care, breast cancer remains one of the leading causes of mortality in women worldwide, thus emphasizing the need for better predictive and therapeutic targets. ABI1 is associated with poor survival and an aggressive br
Externí odkaz:
https://doaj.org/article/195f405edb7f4b7589ba1a65f66976c7
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-19 (2021)
Abstract Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement on SRC function. However, a significant body of work has defined Src family kinases as key players in tumor progression, invasion and metastasis i
Externí odkaz:
https://doaj.org/article/0b134cc45516492eb45b013d718ebd29
Autor:
Disharee Nath, Xiang Li, Claudia Mondragon, Dawn Post, Ming Chen, Julie R. White, Anita Hryniewicz-Jankowska, Tiffany Caza, Vladimir A. Kuznetsov, Heidi Hehnly, Tamara Jamaspishvili, David M. Berman, Fan Zhang, Sonia H. Y. Kung, Ladan Fazli, Martin E. Gleave, Gennady Bratslavsky, Pier Paolo Pandolfi, Leszek Kotula
Publikováno v:
Cell Communication and Signaling, Vol 17, Iss 1, Pp 1-19 (2019)
Abstract Background Prostate cancer development involves various mechanisms, which are poorly understood but pointing to epithelial mesenchymal transition (EMT) as the key mechanism in progression to metastatic disease. ABI1, a member of WAVE complex
Externí odkaz:
https://doaj.org/article/b367179fb38b484e89b1472961698c67
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 3, Iss 2, Pp 99-104 (2001)
The gene encoding human spectrin Src homology domain binding protein 1, or Hssh3bpl, which is a marker of macropinocytic vesicles and a potential regulator of macropinocytosis, co-localizes to a YAC containing chromosome 10p sequences at loci D10S89
Externí odkaz:
https://doaj.org/article/bb776f50fe15428b8c18862f23c0ad77
Autor:
Patrycja M Dubielecka, Ping Cui, Xiaoling Xiong, Sajjad Hossain, Susanne Heck, Lyudmil Angelov, Leszek Kotula
Publikováno v:
PLoS ONE, Vol 5, Iss 5, p e10430 (2010)
Macropinocytosis, which is a constitutive cellular process of fluid and macromolecule uptake, is regulated by actin cytoskeleton rearrangements near the plasma membrane. Activation of Rac1, which is proposed to act upstream of the actin polymerizatio
Externí odkaz:
https://doaj.org/article/a78218453eb64bcd8346bbae95c74712
Autor:
Baylee A. Porter, Xiang Li, Neeru Arya, Fan Zhang, Sonia H.Y. Kung, Ladan Fazli, Htoo Zarni Oo, Yinan Li, Kenneth Marincin, Konsta Kukkonen, Henna Urhonen, Maria A. Ortiz, Allysa P. Kemraj, Eva Corey, Xuesen Dong, Vladimir A. Kuznetsov, Matti Nykter, Martin E. Gleave, Gennady Bratslavsky, Alfonso Urbanucci, Dominique Frueh, Alaji Bah, Leszek Kotula
Transcription regulates key functions of living organisms in normal and disease states, including cell growth and development, embryonic and adult tissue organization, and tumor progression. Here we identify a novel mechanism of transcriptional regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a432621e95cbfe991ae0315337679352
https://doi.org/10.1101/2023.05.26.542350
https://doi.org/10.1101/2023.05.26.542350
Autor:
Max Petersen, Anna Chorzalska, Makayla Pardo, Anaelena Rodriguez, John Morgan, Nagib Ahsan, Ting C. Zhao, Olin Liang, Leszek Kotula, Paul Bertone, Philip A. Gruppuso, Patrycja M. Dubielecka
Publikováno v:
Molecular Oncology.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::578e1353840b113a9f78c53e2cec5c9e
https://doi.org/10.1002/1878-0261.13374
https://doi.org/10.1002/1878-0261.13374
Publikováno v:
Cell Communication and Signaling, Vol 19, Iss 1, Pp 1-19 (2021)
Cell Communication and Signaling : CCS
Cell Communication and Signaling : CCS
Over a century of scientific inquiry since the discovery of v-SRC but still no final judgement on SRC function. However, a significant body of work has defined Src family kinases as key players in tumor progression, invasion and metastasis in human c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c58cca66fe7bcfc86a22be3d279866
https://doaj.org/article/0b134cc45516492eb45b013d718ebd29
https://doaj.org/article/0b134cc45516492eb45b013d718ebd29
Autor:
Robert Adamiecki, Anita Hryniewicz-Jankowska, Maria A. Ortiz, Xiang Li, Baylee A. Porter-Hansen, Imad Nsouli, Gennady Bratslavsky, Leszek Kotula
In 2022, prostate cancer (PCa) is estimated to be the most commonly diagnosed cancer in men in the United States—almost 270,000 American men are estimated to be diagnosed with PCa in 2022. This review compares and contrasts in vivo models of PCa wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b83ccf77c897574d9c0b4d9ecc5085d8