Zobrazeno 1 - 10
of 160
pro vyhledávání: '"Leszek, Rychlewski"'
Autor:
Alicja Anna Binkowska, Anastasia Ruban, Mariszka Gogolewska, Piotr Sawicz, Leszek Rychlewski, Aneta Brzezicka
Publikováno v:
Journal of Addictions Nursing. 33:37-44
Although frequency of cannabis use is considered to be the strongest risk factor for developing cannabis dependence, only up to half of daily users become dependent. In this study, we explored an array of risk factors and moderators of cannabis depen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f77d2c318fda1344651a404243c0ed5
https://doi.org/10.1097/jan.0000000000000448
https://doi.org/10.1097/jan.0000000000000448
Autor:
Frank Breitling, Carolin Geiger, Ali Sié, Lucjan Wyrwicz, Peter H. Seeberger, Kirsten Heiss, Thomas Jaenisch, Nico Fischer, Boubacar Coulibaly, Leszek Rychlewski, Felix F. Loeffler, Gerhard Moldenhauer, F. Ralf Bischoff
Publikováno v:
Molecular & Cellular Proteomics. 18:642-656
High-density peptide arrays are an excellent means to profile anti-plasmodial antibody responses. Different protein intrinsic epitopes can be distinguished, and additional insights are gained, when compared with assays involving the full-length prote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7b8c74d6386fe40ad01b1fe2cd5f8c
https://doi.org/10.1074/mcp.ra118.000992
https://doi.org/10.1074/mcp.ra118.000992
Autor:
Leszek Rychlewski, Joanna Grzesik, Jarosław Dastych, Marta Borowiec, Krzysztof Ginalski, Ewelina Rodakowska, Aurelia Walczak‑Drzewiecka, Marcin Ratajewski, Michal Rozanski, Michał Gorzkiewicz
Publikováno v:
Oncology Letters. 21
Glypican-3 (GPC3) is a cell membrane glycoprotein that regulates cell growth and proliferation. Aberrant expression or distribution of GPC3 underlies developmental abnormalities and the development of solid tumours. The strongest evidence for the par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::08a8b9b81df5fe27b9976865e27ce798
https://doi.org/10.3892/ol.2021.12483
https://doi.org/10.3892/ol.2021.12483
Autor:
Marta Borowiec, Michal Gorzkiewicz, Joanna Grzesik, Aurelia Walczak-Drzewiecka, Anna Salkowska, Ewelina Rodakowska, Kamil Steczkiewicz, Leszek Rychlewski, Jaroslaw Dastych, Krzysztof Ginalski
Publikováno v:
Toxins, Vol 8, Iss 11, p 321 (2016)
Exotoxin A (PE) from Pseudomonas aeruginosa is a bacterial ADP-ribosyltransferase, which can permanently inhibit translation in the attacked cells. Consequently, this toxin is frequently used in immunotoxins for targeted cancer therapies. In this stu
Externí odkaz:
https://doaj.org/article/be8495e1145040e08ea0bf1ad16657c1
Autor:
Ewelina, Rodakowska, Aurelia, Walczak-Drzewiecka, Marta, Borowiec, Michal, Gorzkiewicz, Joanna, Grzesik, Marcin, Ratajewski, Michal, Rozanski, Jaroslaw, Dastych, Krzysztof, Ginalski, Leszek, Rychlewski
Publikováno v:
Oncology Letters
Glypican-3 (GPC3) is a cell membrane glycoprotein that regulates cell growth and proliferation. Aberrant expression or distribution of GPC3 underlies developmental abnormalities and the development of solid tumours. The strongest evidence for the par
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ecf5e222b5e48b74b00485ce285673e8
https://pubmed.ncbi.nlm.nih.gov/33613711
https://pubmed.ncbi.nlm.nih.gov/33613711
Autor:
Tomasz Wlodarski, Jan Kutner, Joanna Towpik, Lukasz Knizewski, Leszek Rychlewski, Andrzej Kudlicki, Maga Rowicka, Andrzej Dziembowski, Krzysztof Ginalski
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e23168 (2011)
Methylation is one of the most common chemical modifications of biologically active molecules and it occurs in all life forms. Its functional role is very diverse and involves many essential cellular processes, such as signal transduction, transcript
Externí odkaz:
https://doaj.org/article/c05fd22c0ce54cf597fe793b0ffb6cc2
Autor:
Gabriele Möller, Bettina Husen, Dorota Kowalik, Leena Hirvelä, Dariusz Plewczynski, Leszek Rychlewski, Josef Messinger, Hubert Thole, Jerzy Adamski
Publikováno v:
PLoS ONE, Vol 5, Iss 6, p e10969 (2010)
Steroid-related cancers can be treated by inhibitors of steroid metabolism. In searching for new inhibitors of human 17beta-hydroxysteroid dehydrogenase type 1 (17beta-HSD 1) for the treatment of breast cancer or endometriosis, novel substances based
Externí odkaz:
https://doaj.org/article/06b4b6d915cf4e4aa8a692666c9b6054
Autor:
Małgorzata Giel-Pietraszuk, Miroslawa Z. Barciszewska, Iwona Łętowska, Mirosława Skupińska, Jan Barciszewski, Leszek Rychlewski, Piotr Stępniak
Publikováno v:
Microbial Drug Resistance. 23:308-320
Tyrosyl-tRNA synthetases (TyrRSs) as essential enzymes for all living organisms are good candidates for therapeutic target in the prevention and therapy of microbial infection. We examined the effect of various polyphenols, alkaloids, and terpenes-se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed8f833fb1782a997b1c23a1475a557a
https://doi.org/10.1089/mdr.2015.0272
https://doi.org/10.1089/mdr.2015.0272
Publikováno v:
Optimization Letters. 8:1783-1794
3D-Hit is a well established method for rapid detection of structural similarities between proteins, which is widely used in various bioinformatics web servers (MetaServer, GRDB, 3D-Fun, Rosetta, etc.). The algorithm decomposes proteins into set of o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d7201d7dade67a451076e4de9d4c56d
https://doi.org/10.1007/s11590-013-0697-3
https://doi.org/10.1007/s11590-013-0697-3
Autor:
Leszek Rychlewski, Marco W. Fraaije, G. de Gonzalo, Anette Riebel, Hanna M. Dudek, Piotr Stępniak
Publikováno v:
Applied Microbiology and Biotechnology
Applied Microbiology and Biotechnology, 95(6), 1479-1489. SPRINGER
Applied Microbiology and Biotechnology, 95(6), 1479-1489. SPRINGER
To expand the available set of Baeyer–Villiger monooxygenases (BVMOs), we have created expression constructs for producing 22 Type I BVMOs that are present in the genome of Rhodococcus jostii RHA1. Each BVMO has been probed with a large panel of po
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d7674d48e8f9b55da54deec162f8d81
https://hdl.handle.net/11370/d761d58a-ab47-482b-9198-f4f169d37433
https://hdl.handle.net/11370/d761d58a-ab47-482b-9198-f4f169d37433