Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Lester Kwock"'
Publikováno v:
The American Journal of Clinical Nutrition. 92:1113-1119
Background: Choline is obtained from the diet and from the biosynthesis of phosphatidylcholine. Phosphatidylcholine is catalyzed by the enzyme phosphatidylethanolamine-N-methyltransferase (PEMT), which is induced by estrogen. Because they have lower
Publikováno v:
Scopus-Elsevier
Europe PubMed Central
Europe PubMed Central
While malignant brain tumors typically show high choline concentrations and neovascularity, we have anecdotally noted that a substantial number of brain metastases from lung cancer demonstrate only mildly elevated choline resonances on proton MR spec
Publikováno v:
Journal of Computer Assisted Tomography. 31:682-687
Background and purpose Pilomyxoid astrocytomas (PMAs) have been described only recently. They appear as low-grade tumors sharing imaging features similar to pilocytic astrocytomas (PAs). However, pilomyxoid astrocytomas have different histological fe
Autor:
Leslie M. Fischer, Paul W. Stewart, Lester Kwock, Sally P. Stabler, Steven H. Zeisel, Tsui Shan Lu, Kerry Ann daCosta, Robert H. Allen
Publikováno v:
The American Journal of Clinical Nutrition. 85:1275-1285
Background Although humans require dietary choline for methyl donation, membrane function, and neurotransmission, choline can also be derived from the de novo synthesis of phosphatidylcholine, which is up-regulated by estrogen. A recommended Adequate
Autor:
John Grimme, Matthew G. Ewend, J. Keith Smith, Mauricio Castillo, Lester Kwock, M. Vittoria Spampinato, Daniel L. A. Camacho
Publikováno v:
American Journal of Roentgenology. 188:204-212
The purpose of this study was to determine whether perfusion-weighted imaging (PWI) and proton MR spectroscopy (MRS) are useful in differentiating high- and low-grade oligodendroglial tumors.PWI and MRS studies of 22 patients with histologically prov
Autor:
J. Keith Smith, Lester Kwock, Matthew G. Ewend, David E. Morris, Mauricio Castillo, Sharon Cush, Thomas W. Bouldin, Frances A. Collichio
Publikováno v:
The Lancet Oncology. 7:859-868
Standardised proton magnetic resonance spectroscopic imaging (MRSI) was initially developed for routine in-situ clinical assessment of human brain tumours, and its use was later extended for examination of prostate and breast cancers. MRSI coupled wi
Autor:
Lester Kwock, Martin Kohlmeier, Jiannan Song, Steven H. Zeisel, Kerry Ann Da Costa, Shuli Wang, Leslie M. Fischer
Publikováno v:
The FASEB Journal. 19:1266-1271
Phosphatidylethanolamine N-methyltransferase (PEMT) catalyzes phosphatidylcholine synthesis. PEMT knockout mice have fatty livers, and it is possible that, in humans, nonalcoholic fatty liver disease (NAFLD) might be associated with PEMT gene polymor
Publikováno v:
Neuroradiology. 44:825-829
The imaging findings of brain-stem lesions are often nonspecific and histological diagnosis is limited because of fear of complications associated with biopsy. A noninvasive method for tissue characterization is therefore highly desirable. We underto
Autor:
Lester Kwock, Mauricio Castillo
Publikováno v:
Topics in Magnetic Resonance Imaging. 10:104-113
Publikováno v:
Magnetic Resonance Imaging Clinics of North America. 6:1-20
The basic principles of proton MR spectroscopy as well as newer and more advanced related techniques are reviewed. Spectroscopy is capable of differentiating normal from pathologic brain and provides tissue specificity greater than that of imaging in