Zobrazeno 1 - 10
of 162
pro vyhledávání: '"Lester F. Lau"'
Publikováno v:
Hepatology Communications, Vol 6, Iss 10, Pp 2798-2811 (2022)
Abstract Following inflammatory injury in the liver, neutrophils quickly infiltrate the injured tissue to defend against microbes and initiate the repair process; these neutrophils are short lived and rapidly undergo apoptosis. Hepatic stellate cells
Externí odkaz:
https://doaj.org/article/e8dcd85156b4433e868f7b078f239308
Publikováno v:
JCI Insight, Vol 7, Iss 14 (2022)
Senescent cells have long been associated with deleterious effects in aging-related pathologies, although recent studies have uncovered their beneficial roles in certain contexts, such as wound healing. We have found that hepatic stellate cells (HSCs
Externí odkaz:
https://doaj.org/article/b23b4b715faa42219b444b5d54d8ce62
Autor:
Joon-Il Jun, Lester F. Lau
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
CCN1 is a matricellular protein with a variety of functions, including an effect on wound healing and an association with inflammation. Here, the authors identify a possible mechanism by showing that CCN1 mediates the clearance of bacterial infection
Externí odkaz:
https://doaj.org/article/484bcf6fc0ac4f8cace309d830686ffe
Autor:
Sangmi Lee, Menna Elaskandrany, Lester F. Lau, Douglas Lazzaro, Maria B. Grant, Brahim Chaqour
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract CYR61-CTGF-NOV (CCN)1 is a dynamically expressed extracellular matrix (ECM) protein with critical functions in cardiovascular development and tissue repair. Angiogenic endothelial cells (ECs) are a major cellular source of CCN1 which, once s
Externí odkaz:
https://doaj.org/article/081b1e69b3a246369c5c4a860c3ee750
Autor:
Yanzhuang Li, Lester F. Lau
Publikováno v:
BioTechniques, Vol 28, Iss 3, Pp 577-581 (2000)
An isopropyl β-d-thiogalactopyranoside (IPTG)-inducible episomal expression system has been established for the human breast carcinoma cell line MCF7. This two-component system includes: (i) a primate cell-specific episomal vector, pEpiLac, that con
Externí odkaz:
https://doaj.org/article/d92bb1743cdb4d8499a9c61ed9d5942c
Publikováno v:
BioTechniques, Vol 26, Iss 1, Pp 102-106 (1999)
We describe a simple and rapid protocol for the flow cytometric analysis of the cell cycle in transfected cells using a green fluorescent protein anchored in the intracellular membranes of the endoplasmic reticulum (ER-GFP) as a transfection marker.
Externí odkaz:
https://doaj.org/article/c5eb97a61ba44c94be984427c1896a76
Autor:
Lester F. Lau, Ricardo I. Monzon, Vladislava Juric, Viktor Todorović, Chih-Chiun Chen, Carrie A. Franzen
Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) plays an important role in immune surveillance and preferentially induces apoptosis in cancer cells over normal cells, suggesting its potential in cancer therapy. However, the molecular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fdb0ec90668bffd43ad23a1d2877bb2
https://doi.org/10.1158/1541-7786.c.6542295.v1
https://doi.org/10.1158/1541-7786.c.6542295.v1
Autor:
Lester F. Lau, Ricardo I. Monzon, Vladislava Juric, Viktor Todorović, Chih-Chiun Chen, Carrie A. Franzen
Supplementary Data from Matrix Protein CCN1 Is Critical for Prostate Carcinoma Cell Proliferation and TRAIL-Induced Apoptosis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cef8c18a38db57ae395afe19b0f03d97
https://doi.org/10.1158/1541-7786.22519104
https://doi.org/10.1158/1541-7786.22519104
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::677deb6281b3dee5cad43593af3931d3
https://doi.org/10.1007/978-1-0716-2744-0_14
https://doi.org/10.1007/978-1-0716-2744-0_14
Autor:
Brahim Chaqour, Maria B. Grant, Lester F. Lau, Biran Wang, Mateusz M. Urbanski, Carmen V. Melendez-Vasquez
Publikováno v:
Methods in Molecular Biology ISBN: 9781071627433
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d07b06bafc907c9c59cc18340dbcad58
https://doi.org/10.1007/978-1-0716-2744-0_22
https://doi.org/10.1007/978-1-0716-2744-0_22