Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lestat Ali"'
Autor:
Jennifer Wang, Michael Dougan, Elisa Bello, Marc Pelletier, Li Qiang, Stephanie Dougan, Victoire Cardot-Ruffino, Megan Hoffman, Lestat Ali, Jaime Ivan Castillo Silva, Ayantu Temesgen, Patrick Lenehan, Lauren Kageler, Giselle Uribe, Annan Yang, Andrew J Aguirre, Srivatsan Raghavan, Viviana Cremasco
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/ff64778eaac041e6a7e1d1f59965cbcd
Autor:
Stephanie K. Dougan, Hidde L. Ploegh, Ulrich H. von Andrian, Quang-De Nguyen, Mohammad Rashidian, Mariah M. Servos, Paul M. Tyler, Olga Blomberg, Novalia Pishesha, Lestat Ali, Patrick T. Bruck, Munir M. Mosaheb, Hee-Jin Jeong, Jessica R. Ingram, Michael Dougan
S6. A12-IFNγ alters the tumor microenvironment in KPC organoid model of pancreatic cancer.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eeab2ddf65065bd70c2ec3f5c4c9796
https://doi.org/10.1158/2326-6066.22540097
https://doi.org/10.1158/2326-6066.22540097
Autor:
Stephanie K. Dougan, Michael Dougan, Glenn Dranoff, Richard S. Blumberg, Mark A. Exley, Patrick T. Bruck, Lestat Ali, Eleanor Clancy-Thompson
Inhibitor of apoptosis protein (IAP) antagonists are in clinical trials for a variety of cancers, and mouse models show synergism between IAP antagonists and anti–PD-1 immunotherapy. Although IAP antagonists affect the intrinsic signaling of tumor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e763bdfda569dda447567915dfdce055
https://doi.org/10.1158/2326-6066.c.6549145.v1
https://doi.org/10.1158/2326-6066.c.6549145.v1
Autor:
Stephanie K. Dougan, Michael Dougan, Glenn Dranoff, Richard S. Blumberg, Mark A. Exley, Patrick T. Bruck, Lestat Ali, Eleanor Clancy-Thompson
S4: CD1d knockout mice show a significant contribution of the costimulatory effects of LBW-242 on cytokine production by CD4+ T cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d116b85c63ddf3f6d029bc4e8ef0722
https://doi.org/10.1158/2326-6066.22539619
https://doi.org/10.1158/2326-6066.22539619
Autor:
Stephanie K. Dougan, Michael Dougan, Glenn Dranoff, Richard S. Blumberg, Mark A. Exley, Patrick T. Bruck, Lestat Ali, Eleanor Clancy-Thompson
Figure legends
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b10f9a58d49197389d49e91733c9545
https://doi.org/10.1158/2326-6066.22539616
https://doi.org/10.1158/2326-6066.22539616
Autor:
Stephanie K. Dougan, Hidde L. Ploegh, Ulrich H. von Andrian, Quang-De Nguyen, Mohammad Rashidian, Mariah M. Servos, Paul M. Tyler, Olga Blomberg, Novalia Pishesha, Lestat Ali, Patrick T. Bruck, Munir M. Mosaheb, Hee-Jin Jeong, Jessica R. Ingram, Michael Dougan
Cytokine-based therapies for cancer have not achieved widespread clinical success because of inherent toxicities. Treatment for pancreatic cancer is limited by the dense stroma that surrounds tumors and by an immunosuppressive tumor microenvironment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a71fd01468783f14b9fc002e6399036
https://doi.org/10.1158/2326-6066.c.6549281
https://doi.org/10.1158/2326-6066.c.6549281
Autor:
Li Qiang, Stephanie Dougan, Samantha Liu, Gabrielle Ro, Michael Dougan, Lestat Ali, Patrick Lenehan, Felix Hambitzer
Publikováno v:
Regular and Young Investigator Award Abstracts.
Autor:
Li Qiang, Lestat Ali, Meggie Hoffman, Jaime Ivan Castillo Silva, Patrick Lenehan, Elisa Bello, Marc Pelletier, Viviana Cremasco, Stephanie Dougan
Publikováno v:
Cancer Research. 82:C029-C029
TGFβ plays a critical role in promoting pancreatic tumor progression, attenuating CD8 T cell proliferation and cytokine production, enhancing the differentiation of myofibroblasts and the deposition of extracellular matrix. However, single agent TGF
Autor:
Megan T. Hoffman, Patrick J. Lenehan, Jennifer Wang, Lestat Ali, Li Qiang, Amiko Uchida, Sara Vayrynen, Andressa Dias Costa, Michael Dougan, Max Heckler, Jonathan Nowak, Brian W. Wolpin, Stephanie K. Dougan
Publikováno v:
Cancer Research. 82:B018-B018
Pancreatic ductal adenocarcinoma (PDA) is the third most common cause of cancer death in the US with a 11% 5-year survival rate. A key contributor of this dismal prognosis is early and frequent metastatic spread with limited treatment options for pat
Autor:
Li Qiang, Samantha Liu, Gabrielle Ro, Lestat Ali, Patrick Lenehan, Felix Hambizer, Michael Dougan, Stephanie Dougan
Publikováno v:
Cancer Research. 82:C082-C082
Macrophages can be repolarized to promote tumor destruction, particularly by triggering tumoricidal phagocytosis of cancer cells. Despite the increasing interest in monoclonal antibody therapies targeting tumor antigens to drive cancer cell eliminati