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Akademický článek

Transition Metal‐Driven Selectivity in Direct C−H Arylation of Imidazo[2,1‐b]Thiazole

Autor: Dr. Antonio Del Vecchio, Elisabetta Rosadoni, Lorenzo Ballerini, Dr. Angela Cuzzola, Prof. Filippo Lipparini, Dr. Paolo Ronchi, Dr. Sara Guariento, Dr. Matteo Biagetti, Prof. Marco Lessi, Prof. Fabio Bellina

Publikováno v: ChemistryOpen, Vol 13, Iss 11, Pp n/a-n/a (2024)

Abstract A selective direct arylation of the different Csp2‐H bonds of imidazo[2,1‐b]thiazole with (hetero) aryl halides can be achieved simply by switching from a palladium catalyst system to the use of stoichiometric amounts of copper. The obse

Externí odkaz: https://doaj.org/article/7eabd614b0fc4753bc1c3be67f640666

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Akademický článek

OR-05 - IMPACTO DE REESTRUTURAÇÃO DE PROTOCOLO DE VANCOCINEMIA, UTILIZANDO AUC

Autor: Thais Lopes Santos, Odeli Nicole Encinas Sejas, Laura Batista Campos, Maikon Leal Tomé, Guilherme Scodellari Bettencour, Iza Regina Gomes Pereira, Leonardo Barbosa Rodrigues, Rosemeire Lima Lessi, Edson Abdala

Publikováno v: Brazilian Journal of Infectious Diseases, Vol 28, Iss , Pp 103883- (2024)

Introdução: Vancomicina possui estreito índice terapêutico, e sua ineficácia e toxicidade estão diretamente relacionadas a níveis séricos inadequados. Diretrizes publicadas em 2020 reconhecem que o uso da AUC (área sob a curva) entre 400 e 6

Externí odkaz: https://doaj.org/article/be5d116e4d544a32aa40d6d8db349fb1

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Akademický článek

EP-210 - MONITORAMENTO DO NÍVEL SÉRICO DE VANCOMICINA REALIZADO PELO FARMACÊUTICO CLÍNICO EM UM HOSPITAL GERAL DE GRANDE PORTE

Autor: Laura Batista Campos, Thais Lopes Santos, Guilherme Scodelario Bettencourt, Ronaldo Rodrigues de Souza, Maikon Leal Tomé, Iza Regina G. Pereira, Jennifer Rodrigues de Lima, Odeli Nicole Encinas Sejas, Rosemeire Lima Lessi, Edson Abdala

Publikováno v: Brazilian Journal of Infectious Diseases, Vol 28, Iss , Pp 104129- (2024)

Introdução: A vancomicina é um glicopeptídeo, indicado para tratamento de infecções graves por bactérias gram-positivas, principalmente Staphylococcus aureus resistentes à meticilina (MRSA). Todavia, alcançar uma dose apropriada requer monit

Externí odkaz: https://doaj.org/article/0ebee3792c544326871b904ab607636b

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Akademický článek

Outcome of adult acute myeloid leukemia patients with extramedullary disease and treatment with venetoclax / hypomethylating agents

Publikováno v: Haematologica, Vol 999, Iss 1 (2024)

We evaluated response to VEN/HMA in 46 patients with acute myeloid leukemia (AML) characterized by extramedullary disease (EMD). Median age was 65 (range, 19-81) years. Patients had a median of two EMD sites (range, 1-5) and 35 (76%) patients had con

Externí odkaz: https://doaj.org/article/c5e4bbe9039445ce81f108582a7f9cc3

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Akademický článek

Bird richness and Ecosystems Services across an urban to natural gradient in south-eastern Brazil: implications for landscape planning and future scenarios

Autor: Bruno Lessi, Davide Geneletti, Chiara Cortinovis, Manoel Dias, Matheus Reis

Publikováno v: One Ecosystem, Vol 9, Iss , Pp 1-26 (2024)

In natural and altered environments, the Ecosystem Services (ES) provided by the presence of vegetation, especially regulating ES such as climate regulation and air pollutant removal, are essential to improve human health and well-being. In this stud

Externí odkaz: https://doaj.org/article/37f1493e47ae40c18f754a85967f1983

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Report

Microwave frequency dissemination systems as sensitive and low-cost interferometers for earthquake detection on commercially deployed fiber cables

Autor: Bogris, Adonis, Simos, Christos, Simos, Iraklis, Nikas, Thomas, Melis, Nikolaos S., Lentas, Konstantinos, Mesaritakis, Charis, Chochliouros, Ioannis, Lessi, Christina

We experimentally demonstrate a microwave frequency dissemination system operating as a sensitive interferometric sensor of seismic waves on commercially deployed fiber networks in Attika, Greece. Efficient detection of seismic waves from distant epi

Externí odkaz: http://arxiv.org/abs/2111.02957

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Akademický článek

Development of eggplant seedlings under different doses of biostimulant derived from Ascophyllum nodosum

Autor: Dênis Antônio Rocha Júnior, Juvenal Rodrigues Silva Júnior, José Augusto Pereira Neto, João Paulo Mendes Ferreira, Fhilipe Cogo Andrade, Luis Lessi dos Reis

Publikováno v: Revista Agrogeoambiental, Vol 16, Iss unico (2024)

Eggplant (Solanum melongena L.) belongs to the Solanaceae family and is among the 10 most consumed vegetables in Brazil. Among the cultivation systems, the production of seedlings is one of the most important steps to obtain quality plants and to red

Externí odkaz: https://doaj.org/article/8c5c8944b3df4c5390e9570df3586410

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Akademický článek

Efficacy and safety of venetoclax plus hypomethylating agents in relapsed/refractory acute myeloid leukemia: a multicenter real-life experience

Autor: Francesco Angotzi, Federica Lessi, Matteo Leoncin, Carla Filì, Mauro Endri, Albana Lico, Andrea Visentin, Stefano Pravato, Anna Candoni, Livio Trentin, Carmela Gurrieri

Publikováno v: Frontiers in Oncology, Vol 14 (2024)

Venetoclax (VEN) has been shown to play a synergistic effect in combination with hypomethylating agents (HMAs) in the frontline treatment of acute myeloid leukemia (AML). However, the potential role of this therapy in the relapsed/refractory (R/R) AM

Externí odkaz: https://doaj.org/article/1dc19f49a1674f73b8dadeba5d415a59

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