KLF15 controls brown adipose tissue transcriptional flexibility and metabolism in response to various energetic demands.

Autor: Fan L; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA., Lesser AF; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA., Sweet DR; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.; Department of Pathology, Case Western Reserve University, Cleveland, OH 44106, USA., Keerthy KS; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA., Lu Y; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA.; Charles River Laboratories, Ashland, OH 44805, USA., Chan ER; Institute for Computational Biology, Case Western Reserve University, Cleveland, OH 44106, USA., Vinayachandran V; Case Cardiovascular Research Institute, Case Western Reserve University, and Harrington Heart and Vascular Institute, University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA., Ilkayeva O; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Das T; Division of Biology and Medicine, Warren Alpert Medical School of Brown University, Providence, IR 02903, USA., Newgard CB; Sarah W. Stedman Nutrition and Metabolism Center and Duke Molecular Physiology Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine and Pharmacology and Cancer Biology, Duke University School of Medicine, Durham, NC 27710, USA., Jain MK; Division of Biology and Medicine, Warren Alpert Medical School of Brown University, Providence, IR 02903, USA.

Publikováno v: IScience [iScience] 2022 Oct 08; Vol. 25 (11), pp. 105292. Date of Electronic Publication: 2022 Oct 08 (Print Publication: 2022).