Effects of Hypothermia vs Normothermia on Societal Participation and Cognitive Function at 6 Months in Survivors After Out-of-Hospital Cardiac Arrest: A Predefined Analysis of the TTM2 Randomized Clinical Trial.

Autor: Lilja G; Clinical Studies Sweden, Forum South, Skane University Hospital, Lund, Sweden., Ullén S; Clinical Studies Sweden, Forum South, Skane University Hospital, Lund, Sweden., Dankiewicz J; Cardiology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden., Friberg H; Anesthesia and Intensive Care, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Malmö, Sweden., Levin H; Anesthesia and Intensive Care, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Malmö, Sweden., Nordström EB; Neurology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden., Heimburg K; Neurology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden., Jakobsen JC; Copenhagen Trial Unit, Center for Clinical Intervention Research, Copenhagen University Hospital, Copenhagen, Denmark.; Department of Regional Health Research, The Faculty of Health Sciences, University of Southern Denmark, Denmark., Ahlqvist M; Department of Anaesthesiology and Intensive Care Medicine, Institute of Clinical Sciences, Sahlgrenska Academy, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden., Bass F; Critical Care Program, The George Institute for Global Health and UNSW Sydney, Sydney, New South Wales, Australia.; Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Sydney, New South Wales, Australia., Belohlavek J; 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic., Olsen RB; Department of Anesthesiology, Sørlandet Hospital, Arendal, Norway., Cariou A; Cochin University Hospital (APHP) and Paris Cité University (medical school), Paris, France., Eastwood G; Department of Intensive Care, Austin Hospital, Melbourne, Victoria, Australia., Fanebust HR; Cardiac Intensive Care Unit, Haukeland University Hospital, Bergen, Norway., Grejs AM; Department of Intensive Care Medicine and Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Grimmer L; University Hospitals Bristol and Weston NHS Trust, Bristol, United Kingdom., Hammond NE; Critical Care Program, The George Institute for Global Health and UNSW Sydney, Sydney, New South Wales, Australia.; Malcolm Fisher Department of Intensive Care, Royal North Shore Hospital, Sydney, New South Wales, Australia., Hovdenes J; Department of Anesthesiology, Division of Emergencies and Critical Care, Oslo University Hospital, Rikshospitalet, Oslo, Norway., Hrecko J; The 1st Department of Internal Medicine, Cardioangiology, Medical Faculty of Charles University in Hradec Králové and University Hospital Hradec Králové, Hradec Králové, Czech Republic., Iten M; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Johansen H; Department of Neurology, Rikshospitalet, Oslo University Hospital, Oslo, Norway., Keeble TR; Essex Cardio Thoracic Centre, Basildon, Essex, UK Thurrock University Hospitals, Basildon, United Kingdom.; MTRC, Anglia Ruskin University Faculty of Health Education Medicine & Social Care, Chelmsford, Essex, United Kingdom., Kirkegaard H; Research Center for Emergency Medicine, Emergency Department Aarhus University Hospital and Department of Clinical Medicine Aarhus University, Aarhus, Denmark., Lascarrou JB; Medecine Intensive Reanimation, CHU Nantes, Nantes, France., Leithner C; Charité- Universitätsmedizin Berlin, coroporate member of Freie Universität Berlin and Humboldt- Universität-zu-Berlin, Department of Neurology, Berlin, Germany., Lesona ME; Intensive Care Unit, Wellington hospital, Wellington, New Zealand., Levis A; Department of Intensive Care Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.; Department of Anesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Mion M; Essex Cardio Thoracic Centre, Basildon, Essex, UK Thurrock University Hospitals, Basildon, United Kingdom.; MTRC, Anglia Ruskin University Faculty of Health Education Medicine & Social Care, Chelmsford, Essex, United Kingdom., Moseby-Knappe M; Neurology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden., Navarra L; Medical Research Institute of New Zealand, Wellington, New Zealand., Nordberg P; Center for Resuscitation Sciences, Department of Clinical Science and Education, Södersjukhuset, Karolinska Institutet, Stockholm, Sweden.; Function Perioperative Medicine and Intensive Care, Karolinska University Hospital, Stockholm, Sweden., Pelosi P; Department of Surgical Sciences and Integrated Diagnostics, University of Genoa, Genoa, Italy.; Anesthesia and Critical Care, San Martino Policlinico Hospital, IRCCS for Oncology and Neurosciences, Genoa, Italy., Quayle R; Manchester Foundation Trust, Manchester, United Kingdom.; The Greater Manchester NIHR Clinical Research Network, Manchester, United Kingdom., Rylander C; Department of Surgical Sciences, Anaesthesiology and Intensive Care Medicine, Uppsala University, Sweden., Sandberg H; Hallands hospital, Halmstad, Sweden., Saxena M; St George Hospital Clinical School, The George institute for Global Health, University of New South Wales, Sydney, New South Wales, Australia., Schrag C; Intensive Care Department, Kantonspital St Gallen, St Gallen, Switzerland., Siranec M; 2nd Department of Medicine-Department of Cardiovascular Medicine, First Faculty of Medicine, Charles University in Prague and General University Hospital in Prague, Czech Republic., Tiziano C; Cardiac anesthesia and Intensive Care department, Istituto Cardiocentro Ticino, Lugano, Switzerland., Vignon P; Medical-surgical ICU and Inserm CIC 1435, Dupuytren University hospital, Limoges, France., Wendel-Garcia PD; Institute of Intensive Care Medicine, University Hospital Zurich, Zurich, Switzerland., Wise MP; Adult Critical Care, University Hospital of Wales, Cardiff, United Kingdom., Wright K; University Hospitals Bristol and Weston NHS Trust, Bristol, United Kingdom., Nielsen N; Department of Clinical Sciences Lund, Anaesthesia and Intensive Care and Clinical Sciences Helsingborg, Helsingborg Hospital, Lund University, Lund, Sweden., Cronberg T; Neurology, Department of Clinical Sciences Lund, Lund University, Skane University Hospital, Lund, Sweden.

Publikováno v: JAMA neurology [JAMA Neurol] 2023 Oct 01; Vol. 80 (10), pp. 1070-1079.