Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Lesnick E. Westrum"'
Autor:
Sara K. Custer, Albert R. La Spada, Bryce L. Sopher, Udo Rueb, Thomas Deller, Christian Schultz, Randell T. Libby, Gwenn A. Garden, Lesnick E Westrum, Stephan J. Guyenet, Nishi Gill
Publikováno v:
Nature Neuroscience. 9:1302-1311
Non-neuronal cells may be pivotal in neurodegenerative disease, but the mechanistic basis of this effect remains ill-defined. In the polyglutamine disease spinocerebellar ataxia type 7 (SCA7), Purkinje cells undergo non-cell-autonomous degeneration i
Publikováno v:
Annals of the New York Academy of Sciences. 884:389-409
Hearing loss induced by ototoxicity is a worldwide problem despite the development of newer antibiotics and chemotherapy agents. The cellular mechanisms responsible for aminoglycoside-induced hearing loss are still poorly understood. We have develope
Publikováno v:
Brain Research. 806:16-25
Postembedding immunogold methods were used to examine the distribution of gamma-aminobutyric acid (GABA) and glycine and especially their colocalization in glomerular neuronal profiles adjacent to trigeminal primary afferent profiles in lamina II of
Publikováno v:
Experimental Neurology. 143:219-230
Juxtaglomerular (JG) neurons of rat olfactory bulb (OB) are a subset of inhibitory interneurons within the OB, acting via lateral inhibition to modulate the afferent input of the primary olfactory nerve. The JG neurons, composed of periglomerular, ex
Publikováno v:
Synapse. 24:48-59
This report uses lesion and postembedding immunogold protocols to examine the ultrastructural details of lesion-induced synaptic and neurotransmitter changes in the feline trigeminal nucleus. Electron microscopic (EM) analysis concentrated on lamina
Publikováno v:
Synapse. 24:39-47
This study examines the normal synaptic organization of the feline spinal trigeminal nucleus pars caudalis (PC). A primary goal of this study is to identify and characterize the synaptic complexes within PC based on their specific neurotransmitter co
Publikováno v:
Synapse. 23:132-141
Juxtaglomerular (JG) neurons of rat olfactory bulb (OB) have been shown to express tyrosine hydroxylase (TH), the rate-limiting enzyme in the catecholamine synthesis pathway. These JG neurons act as inhibitory dopaminergic interneurons, modulating th
Publikováno v:
The Journal of Comparative Neurology. 366:465-477
We studied the ultrastructure of the synaptic organization in the feline spinal trigeminal nucleus, emphasizing specific neurotransmitter patterns within lamina II of the pars caudalis/medullary dorsal horn. Normal adults were perfused, and Vibratome
Publikováno v:
The Journal of Comparative Neurology. 365:526-540
Calcitonin gene-related peptide (CGRP) is a neuropeptide that has been implicated in the transmission and modulation of primary afferent nociceptive stimuli. In this study, we describe the light microscopic distribution of CGRP immunoreactivity (IR)
Publikováno v:
Experimental Neurology. 132:284-290
We are using wheat germ agglutinin-conjugated horseradish peroxidase (WIiRP) to study reconnectivity in the transplanted (TX) olfactory bulb (OB) in Sprague-Dawley rats. Tritium-labeled OBs from fetal rat donors of Embryonic Days 14–15 were immedia