Combined analysis of transcriptomic and genetic data for the identification of loci involved in glucocorticosteroid response in asthma

Autor: Mario Gorenjak, Vojko Berce, Maximilian Schieck, Martin Kerick, Steve Turner, Munir Pirmohamed, Leila Karimi, Almudena Corrales, Staša Jurgec, Marialbert Acosta-Herrera, Katia M.C. Verhamme, Carlos Flores, Natalia Hernandez-Pacheco, Susanne J. H. Vijverberg, Roger Tavendale, Michael Kabesch, Colin N. A. Palmer, Lesly-Anne Samedy-Bates, Jesús Villar, Somnath Mukhopadhyay, Andrea L. Jorgensen, Esteban G. Burchard, Daniel B Hawcutt, Anke H. Maitland-van der Zee, Uroš Potočnik, Maria Pino-Yanes

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
instname
ALLERGY
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1238-1243. Wiley-Blackwell
Allergy
Allergy: European Journal of Allergy and Clinical Immunology, 76(4), 1238-1243. Wiley-Blackwell Publishing Ltd

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8220056986087f468625782b43f34ef
https://pure.eur.nl/en/publications/2ed82638-3683-441d-82b1-733cd3e376b6

Identification of robo2 as a potential locus associated with inhaled corticosteroid response in childhood asthma

Autor: Roger Tavendale, Daniel B Hawcutt, Anke H. Maitland-van der Zee, Maximilian Schieck, Colin N. A. Palmer, Andrea L. Jorgensen, Uroš Potočnik, Carlos Flores, Maria Pino-Yanes, Susanne J. H. Vijverberg, Somnath Mukhopadhyay, Leila Karimi, Jiang Li, Katia M.C. Verhamme, Michael Kabesch, Natalia Hernandez-Pacheco, Mario Gorenjak, Vojko Berce, Kelan G. Tantisira, Katja Repnik, Steve Turner, Lesly Anne Samedy-Bates, Munir Pirmohamed, Esteban G. Burchard, Jesús Villar

Publikováno v: Journal of Personalized Medicine
Journal of Personalized Medicine, Vol 11, Iss 733, p 733 (2021)
Volume 11
Issue 8
Journal of Personalized Medicine, 11(8):733. MDPI Multidisciplinary Digital Publishing Institute
Journal of Personalized Medicine, 11(8):733. Multidisciplinary Digital Publishing Institute (MDPI)

Inhaled corticosteroids (ICS) are the most common asthma controller medication. An important contribution of genetic factors in ICS response has been evidenced. Here, we aimed to identify novel genetic markers involved in ICS response in asthma. A ge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05f715b432d764dcaa77b9660a3e3d77
https://doi.org/10.3390/jpm11080733

Racial/Ethnic‐Specific Differences in the Effects of Inhaled Corticosteroid Use on Bronchodilator Response in Patients With Asthma

Autor: William Rodriguez-Cintron, Shannon Thyne, Thomas J. Nuckton, Lesly Anne Samedy-Bates, Jennifer R. Elhawary, Luisa N. Borrell, Kelley Meade, Maria Pino-Yanes, Celeste Eng, Jose R. Rodriguez-Santana, Sam S. Oh, Andrew M. Zeiger, Rajesh Kumar, Emerita Brigino-Buenaventura, Sandra Salazar, Kirsten Bibbins-Domingo, Marquitta J. White, Harold J. Farber, Tyronda Elliot, Esteban G. Burchard, Denise Serebrisky, Michael A. LeNoir

Publikováno v: Clin Pharmacol Ther
Clinical pharmacology and therapeutics, vol 106, iss 5

American Thoracic Society guidelines recommend inhaled corticosteroid (ICS) therapy, plus a short-acting bronchodilator, in patients with persistent asthma. However, few prior studies have examined the efficacy of this combination in children of all

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1091cf05a865ecb17279702d7fd2bb70
https://doi.org/10.1002/cpt.1555

Native American Ancestry and Air Pollution Interact to Impact Bronchodilator Response in Puerto Rican Children with Asthma

Autor: Scott Huntsman, Pagé C. Goddard, Joaquin Magana, Andrew M. Zeiger, Kevin L. Keys, Neeta Thakur, Marquitta J. White, Andreas M. Neophytou, Donglei Hu, Eunice Lee, Jennifer R. Elhawary, Lesly-Anne Samedy-Bates, Ting Hu, Angel C.Y. Mak, Esteban G. Burchard, Oona Risse-Adams, Celeste Eng, Maria G. Contreras

Publikováno v: Ethn Dis
Ethnicity & disease, vol 31, iss 1

Objective: Asthma is the most common chronic disease in children. Short-acting bronchodilator medications are the most commonly prescribed asthma treatment worldwide, regardless of disease severity. Puerto Rican children display the high­est asthma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f407762cb81dfb91a55a6b9e5f772289
https://pubmed.ncbi.nlm.nih.gov/33519158

Association of Leukotriene Modifier Use and Bronchodilator Response in Puerto Rican and Mexican American Children with Asthma

Autor: Emerita Brigino-Buenaventura, Eric M. Wohlford, Lesly-Anne Samedy-Bates, Marquitta J. White, J.R. Rodriguez-Santana, Denise Serebrisky, Rajesh Kumar, Shannon Thyne, Harold J. Farber, M.A. LeNoir, Luisa N. Borrell, Eunice Y. Lee, W. Rodriguez, Sam S. Oh, E.G. Burchard, Maria Pino-Yanes, Kirsten Bibbins-Domingo

Publikováno v: B52. PEDIATRIC ASTHMA AND ALLERGY.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d80a1fa0f04237e4047e35a09f9ee36c
https://doi.org/10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a3699